Navigation Links
Hope for Progeria - Successfully Validated on Mice, a Treatment Could Soon be Tested on Children
Date:6/30/2008

esis of this fatty acid. In fact, pharmacological molecules are known to block certain stages in this path of synthesis.

After several attempts they noted that a combination of a statin and an aminobisphosphonate could prevent the fixation of the fatty acid to the progerin, and thus reduce its toxicity. The progerin being less toxic, the disease develops more slowly.

Following these encouraging results, a clinical protocol based on this treatment piloted by Nicolas Levy in Marseille (France) is about to start up. It should last 3 years and will concern 15 of the 25 children affected by progeria in Europe. The aim of this protocol is to slow down the progression of the disease and, if possible, prolong the life expectancy - at present very limited - of the children affected.

Article published in Nature Medicine : http://dx.doi.org/10.1038/nm.1786


'/>"/>
SOURCE AFM-Association Francaise contre les Myopathies
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2

Related medicine technology :

1. Novagali Pharma Successfully Enrolls First Patient in U.S. Phase I Clinical Study with CORTIJECT(R) for Diabetic Macular Edema
2. Celator(R) Pharmaceuticals Successfully Uses Nanoparticles to Administer Hydrophobic Drug Combinations
3. NanoBio Corporation Successfully Completes Phase 2b Study in Herpes Labialis
4. New Study Shows LEVITRA Successfully Treats Erectile Dysfunction (ED) in Men with Dyslipidemia, Including High Cholesterol
5. YMed, Inc. Successfully Completes First Clinical Cases With Innovative VascuTraK(TM) II PTA Dilatation Catheter
6. Harvard Medical School-Partners HealthCare Center for Genetics and Genomics Successfully Completes Evaluation of AutoGenomics 2C9-VKORC1 Panel to Assess Warfarin Sensitivity
7. TaiGen Biotechnology Successfully Completes Patient Recruitment for Phase II Trial of Nemonoxacin for Treatment of Adult Community Acquired Pneumonia (CAP)
8. Harvard Medical School-Partners HealthCare Center for Genetics and Genomics Successfully Completes Evaluation of AutoGenomics 2C9-VKORC1 Panel to Assess Warfarin Sensitivity
9. Blood Pressure Lowering Effect of Hypertension Treatment Device Further Validated in New Studies
10. XTL Biopharmaceuticals Announces Completion of Patient Randomization Into the Bicifadine Phase 2b Clinical Trial for the Treatment of Diabetic Neuropathic Pain
11. ABC News NIGHTLINE Features HIFU with Sonablate(R) 500 as Non Invasive Treatment Option for Prostate Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/7/2008)... Showed Larazotide Acetate Prevented Immunologic C...ts with Celiac Disease, Additional Data Indicates ... ORLANDO, Fla., Oct. 7 /- Alba Therap...ical studies this week at the American,College of ...ing. Data from,study CLIN 1001-004, the first Phas...
(Date:10/7/2008)... - Data Presented Today at ACG Annual Scientific ...tCall/ -- Ironwood,Pharmaceuticals, Inc. (formerly...SE: FRX ) today announced the presentation of res... safety and efficacy in 420 patients with,irritabl...is of the data,indicates that once- daily oral dos...
(Date:10/7/2008)...ient, Prospective Randomized Placebo-Controlled Ph...ant Improved Overall Survival., MOUNTAIN VIEW, Ca...peutics has now evaluated the mature Phase II data...idate PROSTVAC(TM) that had been,obtained as part ...nal,Cancer Institute (NCI) in the US., The result...
(Date:10/7/2008)...STGÃ…RD, Denmark, October 7 /PRNewswire-FirstCall/...o-Controlled Phase II Study,Shows Statistically Si...dic has now evaluated the mature phase II data fro...e PROSTVAC(TM) that had been,obtained as part of t...Cancer Institute (NCI) in the US., The results fr...
Breaking Medicine Technology:Alba Therapeutics Presents New Data for Larazotide Acetate at the 2008 American College of Gastroenterology Annual Scientific Meeting 2Alba Therapeutics Presents New Data for Larazotide Acetate at the 2008 American College of Gastroenterology Annual Scientific Meeting 3Alba Therapeutics Presents New Data for Larazotide Acetate at the 2008 American College of Gastroenterology Annual Scientific Meeting 4Alba Therapeutics Presents New Data for Larazotide Acetate at the 2008 American College of Gastroenterology Annual Scientific Meeting 5Alba Therapeutics Presents New Data for Larazotide Acetate at the 2008 American College of Gastroenterology Annual Scientific Meeting 6Ironwood and Forest Present Positive Phase 2b Study Results for Linaclotide in Patients With Irritable Bowel Syndrome With Constipation 2Ironwood and Forest Present Positive Phase 2b Study Results for Linaclotide in Patients With Irritable Bowel Syndrome With Constipation 3Ironwood and Forest Present Positive Phase 2b Study Results for Linaclotide in Patients With Irritable Bowel Syndrome With Constipation 4Ironwood and Forest Present Positive Phase 2b Study Results for Linaclotide in Patients With Irritable Bowel Syndrome With Constipation 5BN ImmunoTherapeutics Announces Positive Mature Phase II Results From Newly Acquired Prostate Cancer Vaccine 2BN ImmunoTherapeutics Announces Positive Mature Phase II Results From Newly Acquired Prostate Cancer Vaccine 3BN ImmunoTherapeutics Announces Positive Mature Phase II Results From Newly Acquired Prostate Cancer Vaccine 4Bavarian Nordic Announces Positive Mature Phase II Results From Newly Acquired Prostate Cancer Vaccine 2Bavarian Nordic Announces Positive Mature Phase II Results From Newly Acquired Prostate Cancer Vaccine 3Bavarian Nordic Announces Positive Mature Phase II Results From Newly Acquired Prostate Cancer Vaccine 4Bavarian Nordic Announces Positive Mature Phase II Results From Newly Acquired Prostate Cancer Vaccine 5NIST announces 56 new awards for innovative technology research and development 604 1iCAD to Present at William Blair 26 Company Small Cap Growth Stock Conference 2321 1iCAD to Present at William Blair 26 Company Small Cap Growth Stock Conference 2321 2President Bush Should Protect Kids Not Big Tobacco By Signing Bill to Increase Cigarette Tax Fund SCHIP 2318 1President Bush Should Protect Kids Not Big Tobacco By Signing Bill to Increase Cigarette Tax Fund SCHIP 2318 2Jack Anthony to Resign From VaxGens Board After Accepting CEO Position at Osprey Pharmaceuticals 932 1Jack Anthony to Resign From VaxGens Board After Accepting CEO Position at Osprey Pharmaceuticals 932 2
(Date:10/7/2008)...ltrasound similar to more expensive whole-leg colo...AY, Oct. 7 (HealthDay News) -- An older, simpler t...eep vein thrombosis, or DVT -- is as effective as ..., European researchers found that 2-point ultras...on or duplex ultrasound -- was as good at detectin...
(Date:10/7/2008)...riz., Oct. 7 /PRNewswire/ -- Join Mii amo, a desti...elebration in Sedona,s red rock,country honoring t...ude a,series of traditional Native American ceremo...or R.J. Joseph and special guest, Elder George,Goo...oot Elder from the Blood Reserve,in Standoff, Albe...
(Date:10/7/2008)... 100,000 PEOPLE ACROSS THE NATION HAVE SAID ,I VOT... DALLAS, Oct. 7 /PRNewswire/ -- To aid and help e...out the positions of presidential candidates,Senat...e and cancer issues,the Susan G. Komen for the Cu... resources available on its web site --, http://ww...
(Date:10/7/2008)...N, Oct. 7 /PRNewswire-USNewswire/ -- The Catholic ...n conjunction with Catholic,Health Initiatives (CH...;,and Trinity Health, Novi, MI -- is launching a m...l climate change., Through receipt of a $20,000 g...he Environment (NRPE) and the Catholic Coalition o...
Breaking Medicine News(10 mins):Health News:Simpler Test May Be Best for Diagnosing Blood Clots in Leg 2Health News:Simpler Test May Be Best for Diagnosing Blood Clots in Leg 3Health News:Mii amo Honors Winter Solstice With Traditional Native American Celebration December 18-21 2Health News:Susan G. Komen for the Cure(R) Advocacy Alliance Educates Voters, Debate Watchers on McCain/Obama Health Care Agendas 2Health News:Susan G. Komen for the Cure(R) Advocacy Alliance Educates Voters, Debate Watchers on McCain/Obama Health Care Agendas 3Health News:Catholic Health Organizations Launch Ministry-Wide Effort to Raise Awareness About Global Climate Change 2
...sts have developed a scan that could spot the earl...ated illness.// The new machine, which uses techno...of liver damage drinkers may be doing themselves, ...n of Daily Mail. Until now damage could be accurat...
...ing fatty dairy products may actually help in slim... specialists have cautioned people to be wary of s...nvolved in this study. At the end of this study, i...fat free milk had put on more weight when compared...
...re many agencies which are involved in different k...research findings. Each agency may come out with d...the funding agency. In this connection, Dr. David...nd Harvard University says that there are numerous...
...ampsia, an extremely undesirable condition in preg...and child. The condition is said to claim the live...scientists have devised a new diagnostic evaluatio...cting the condition early and saving lives. The r...
Other Medicine News:
...aboratories is a national reference laboratory and...rch and development. ARUP offers an extensive test...n clinical and anatomic pathology. Owned by the Un...de more than half of the nation's university teach...
...aboratories is a national reference laboratory and...rch and development. ARUP offers an extensive test...n clinical and anatomic pathology. Owned by the Un...de more than half of the nation's university teach...
...aboratories is a national reference laboratory and...rch and development. ARUP offers an extensive test...n clinical and anatomic pathology. Owned by the Un...de more than half of the nation's university teach...
...aboratories is a national reference laboratory and...rch and development. ARUP offers an extensive test...n clinical and anatomic pathology. Owned by the Un...de more than half of the nation's university teach...
Medicine Products: