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The MRI results showed that in all patient groups blood flow in the brain was substantially decreased in patients with hypertension compared to those without. Cerebral blood flow was lowest among the Alzheimer's patients with hypertension, but the normal group with hypertension showed significantly lower cerebral blood flow than the normal group without hypertension.
"These results suggest that by changing blood flow to the brain, hypertension -- treated or untreated -- may contribute to the pathology of Alzheimer's," Raji said.
Co-authors are C. Lee, M.D., W. Dai, Ph.D., J.Becker, Ph.D., L. Kuller,
M.D., H. Gach, Ph.D., et al.
AT A GLANCE
-- Hypertension reduces cerebral blood flow in people with Alzheimer's
disease.
-- Arterial spin-labeled MRI is a novel, noninvasive imaging technique
that can measure cerebral blood flow.
-- Approximately 50 million Americans have hypertension.
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RSNA is an association of more than 41,000 radiologists, radiation oncologists, medical physicists and related scientists committed to excellence in patient care through education and research. The Society is based in Oak Brook, Ill. (RSNA.org)
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