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Hernia Publishes a Unique Three Year Pre-Clinical Study of absorbable TIGR® Matrix Surgical Mesh Versus a Permanent Mesh

SINGAPORE, Oct. 6, 2011 /PRNewswire/ -- Novus Scientific today announced the peer-reviewed publication of unique pre-clinical data on TIGR® Matrix Surgical Mesh – the world's first long-term absorbable surgical mesh.

The study, which was presented Online First in Hernia - The World Journal of Hernia and Abdominal Wall Surgery, describes the results of three years of functional implantation of TIGR® Matrix versus a permanent mesh in a sheep model.

This is the longest preclinical evidence ever published on surgical mesh, and it reveals key differences in outcome when comparing TIGR® Matrix to a permanent mesh. As TIGR® Matrix was absorbed over time, it was replaced by connective tissue that had higher collagen content than that surrounding the permanent control mesh. Over time, the foreign-body response to TIGR® Matrix declined significantly while it remained persistent in the control group.

"As TIGR® Matrix is the worlds first long-term absorbable mesh and also the first surgical mesh product with time-dependent mechanical characteristics, we wanted to substantiate how the unique design affects the tissue in terms of regenerated structure and stability." – said Henrik Hjort, first author and co-inventor of TIGR® Matrix. "We believe that the dual-fibre mechanics and resultant gradually increasing compliance can lead to long-lasting results which are indicated by the lack of defect recurrences in this study. A range of clinical studies are underway to examine the results of repair using TIGR® Matrix in a variety of soft tissue reinforcement applications to further demonstrate the benefits to the surgical community."

As stated in the publication: "As the resorbable test mesh gradually degraded it was replaced by a newly formed collagen matrix with an increasing ratio of collagen type I/III, indicating a continuous remodeling of the collagen towards a strong connective tissue." Furthermore: "The general connective tissue layer formed was thicker around the test mesh compared to the control." Hjort H, et al. (2011) Hernia. doi: 10.1007/s10029-011-0885-y.

The study was performed at Biomatech, an independent contract research company that is part of the NAMSA group.

Hernia – The World Journal of Hernia and Abdominal Wall Surgery is published by Springer ( and the article link can be found here:

TIGR® Matrix  Surgical Mesh is available for sale in the U.S. and Europe.

About Novus Scientific

Novus Scientific ( is an innovator in the development and commercialization of resorbable synthetic medical devices. For comprehensive information visit our PRESSROOM:

TIGR® is a trademark of Novus Scientific Pte. Ltd

Mark Hawthorne: +44 7748 988705 -

SOURCE Novus Scientific
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