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Hernia Publishes a Unique Three Year Pre-Clinical Study of absorbable TIGR® Matrix Surgical Mesh Versus a Permanent Mesh
Date:10/6/2011

SINGAPORE, Oct. 6, 2011 /PRNewswire/ -- Novus Scientific today announced the peer-reviewed publication of unique pre-clinical data on TIGR® Matrix Surgical Mesh – the world's first long-term absorbable surgical mesh.

The study, which was presented Online First in Hernia - The World Journal of Hernia and Abdominal Wall Surgery, describes the results of three years of functional implantation of TIGR® Matrix versus a permanent mesh in a sheep model.

This is the longest preclinical evidence ever published on surgical mesh, and it reveals key differences in outcome when comparing TIGR® Matrix to a permanent mesh. As TIGR® Matrix was absorbed over time, it was replaced by connective tissue that had higher collagen content than that surrounding the permanent control mesh. Over time, the foreign-body response to TIGR® Matrix declined significantly while it remained persistent in the control group.

"As TIGR® Matrix is the worlds first long-term absorbable mesh and also the first surgical mesh product with time-dependent mechanical characteristics, we wanted to substantiate how the unique design affects the tissue in terms of regenerated structure and stability." – said Henrik Hjort, first author and co-inventor of TIGR® Matrix. "We believe that the dual-fibre mechanics and resultant gradually increasing compliance can lead to long-lasting results which are indicated by the lack of defect recurrences in this study. A range of clinical studies are underway to examine the results of repair using TIGR® Matrix in a variety of soft tissue reinforcement applications to further demonstrate the benefits to the surgical community."

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SOURCE Novus Scientific
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