Navigation Links
Hereditary Angioedema Patients Report: C1-Esterase Inhibitor Concentrate Effective in Treating Acute Attacks, Helps Them Avoid Emergency Care
Date:11/7/2009

MIAMI BEACH, Fla., Nov. 7 /PRNewswire/ -- Patients reported C1-esterase inhibitor (C1-INH) concentrate is an effective therapy in treating acute swelling attacks at any body location for HAE, a rare and serious genetic disorder, according to data presented today at the 2009 American College of Allergy, Asthma & Immunology (ACAAI) Annual Meeting. The results come from a self-reported survey of patients conducted in parallel with the ongoing, prospective, open label International Multi-center Prospective Angioedema C1-Inhibitor Trial (I.M.P.A.C.T. 2) for C1-INH concentrate. Of the patients surveyed, 98.3 percent reported satisfaction with the treatment, with 37 percent responding that without C1-INH they would have sought emergency treatment and 43 percent would have deferred any medical therapy.

Twenty-eight patients participated in the self-reported survey with responses collected via home computer or telephone voice response. Before the study, these patients reported an annual average of three emergency room visits and four hospital days due to acute attacks. Over 29 months, participants reported 384 attacks (261 abdominal, 71 extremities, eight facial, six genitourinary, 17 laryngeal, and 21 other) with a median of three per patient. C1-INH was used to treat approximately 71 percent of reported attacks. From the start of the attack to C1-INH dosing, the mean time was 12.1 hours (ranging from 0.0 to 189.8 hours) and the mean time from start of treatment to onset of symptom relief was 1.07 hours (ranging from 0.0 to 25.3 hours). The mean time to complete resolution was 18.4 hours (ranging from 1.22 to 471.7 hours).

"Recognizing an acute attack in its early stages is vital in successfully managing the disease," said Robyn J. Levy, M.D., of the Family Allergy & Asthma Center in Atlanta, GA, and the lead investigator of the study. "This survey shows that patients found C1-INH replac
'/>"/>

SOURCE CSL Behring
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. CSL Behring Reaches Primary Endpoint in Clinical Study of C1-INH for Treatment of Hereditary Angioedema
2. Arriva Pharmaceuticals Moves Forward to Phase 2b Development of Lead Inhaled Protein rAAT Replacement Therapy for Hereditary Emphysema
3. CSL Behring Submits BLA Requesting Approval of C1-Esterase Inhibitor for the Treatment of Hereditary Angioedema
4. ViroPharma Announces Presentation of Cinryze(TM) Data in Acute Treatment of Hereditary Angioedema
5. FDA Grants Priority Review of a Supplemental Biologics License Application for Cinryze(TM) C1 Inhibitor (Human) as Treatment for Acute Attacks of Hereditary Angioedema (HAE)
6. Changing Paradigms in Hereditary Angioedema: A Focus on Prompt Diagnosis and New Therapies
7. CSL Behring Announces FDA Approval of Berinert(R), First and Only Therapy Approved for the Treatment of Acute Abdominal and Facial Attacks of Hereditary Angioedema in U.S.
8. Prodromal Symptoms Warn of Hereditary Angioedema Attacks, Give Patients Time to Start Therapy and Decrease Morbidity
9. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
10. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
11. Millennium Initiates Clinical Trial to EVOLVE the Treatment of Patients with Newly Diagnosed Multiple Myeloma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... Laboratories, Inc. (Nasdaq: CBRX ) ("Columbia" ... the three and six-month periods ended June 30, ... from the contribution of the Molecular Profiles services ... an anticipated and temporary decline in product revenues ... in one high-volume, high-margin market. Throughout the renewal ...
(Date:7/31/2014)... 31, 2014 Auxilium Pharmaceuticals, Inc. ... biopharmaceutical company, today announced that the Company will ... its partner Asahi Kasei Pharma Corporation (Asahi Kasei). ... submission of a regulatory application to the Japanese ... ® (collagenase clostridium histolyticum) for the treatment ...
(Date:7/30/2014)...  There is still time to share your ... Annual Institute for Supply Management ® – ... Management is open for submissions.  The annual competition ... of supply management by recognizing supply management organizations ... practices.  Entries are due August 22, 2014. ...
Breaking Medicine Technology:Columbia Laboratories Reports Second Quarter 2014 Financial Results 2Columbia Laboratories Reports Second Quarter 2014 Financial Results 3Columbia Laboratories Reports Second Quarter 2014 Financial Results 4Columbia Laboratories Reports Second Quarter 2014 Financial Results 5Columbia Laboratories Reports Second Quarter 2014 Financial Results 6Columbia Laboratories Reports Second Quarter 2014 Financial Results 7Columbia Laboratories Reports Second Quarter 2014 Financial Results 8Columbia Laboratories Reports Second Quarter 2014 Financial Results 9Columbia Laboratories Reports Second Quarter 2014 Financial Results 10Columbia Laboratories Reports Second Quarter 2014 Financial Results 11Columbia Laboratories Reports Second Quarter 2014 Financial Results 12Auxilium Pharmaceuticals, Inc. Announces XIAFLEX Milestone: Partner Asahi Kasei Pharma Corporation Completes Regulatory Submission For Dupuytren's Contracture In Japan 2Auxilium Pharmaceuticals, Inc. Announces XIAFLEX Milestone: Partner Asahi Kasei Pharma Corporation Completes Regulatory Submission For Dupuytren's Contracture In Japan 3Auxilium Pharmaceuticals, Inc. Announces XIAFLEX Milestone: Partner Asahi Kasei Pharma Corporation Completes Regulatory Submission For Dupuytren's Contracture In Japan 4Auxilium Pharmaceuticals, Inc. Announces XIAFLEX Milestone: Partner Asahi Kasei Pharma Corporation Completes Regulatory Submission For Dupuytren's Contracture In Japan 5Institute for Supply Management, Michigan State University to recognize companies with excellent supply management practices 2
... EAST BRUNSWICK, N.J., Oct. 25 Savient Pharmaceuticals, Inc. (Nasdaq: ... host a conference call on Tuesday, October 26, 2010 at ... detail around its KRYSTEXXA™ launch plans. ... will host a live conference call on October 26, 2010 ...
... The National Community Pharmacists Association (NCPA) today announced ... by Cardinal Health , which found that independent community ... in 2009 despite a stagnant economy, the growing influence ... and the questionable business practices of pharmacy benefit managers ...
Cached Medicine Technology:Savient Pharmaceuticals to Hold Conference Call on October 26, 2010 at 8:30 a.m. Eastern Time 2Savient Pharmaceuticals to Hold Conference Call on October 26, 2010 at 8:30 a.m. Eastern Time 3NCPA Digest Finds Independent Community Pharmacies Stable Despite Economic, Third-Party Challenges 2NCPA Digest Finds Independent Community Pharmacies Stable Despite Economic, Third-Party Challenges 3NCPA Digest Finds Independent Community Pharmacies Stable Despite Economic, Third-Party Challenges 4
(Date:7/31/2014)... 2014 FORT LAUDERDALE, FLORIDA – ... leading US Joint Commission Accredited teleradiology and telemedicine ... technologically advanced consumer storage and sharing platform for ... providing valued members the use of its Cloud-based ... already offered by SecondOpinions.com®. , Wide-spread radiologic ...
(Date:7/31/2014)... Lauderale, FL (PRWEB) July 31, 2014 ... accepting referrals of insurance patients seeking massage therapy in ... company provides an option for Licensed Massage Therapists who ... refer these patients to BWT. Should a patient request ... the referral, BWT can then contract the therapist to ...
(Date:7/31/2014)... (PRWEB) July 31, 2014 What’s ... practice provider? Community Health Center of Snohomish answers ... Pediatricians vs. Family Doctors ”. Many adults can ... available to them. Community Health Center hopes to ... and differences between the two. , To ...
(Date:7/31/2014)... When it comes to aesthetics and wellness, ... As such, Natalie Sharp's Pure Vitality Rx ... new, more focused direction and to provide the latest ... Pure Vitality Rx is Oyster Bay's premier aesthetic, anti-aging ... of services primarily dedicated to women. Services include injectables ...
(Date:7/31/2014)... Some pain relief medications can be as ... Every day, 46 people in the U.S. die from ... people are admitted to an emergency room because of opioid ... the dangers of prescription and over-the-counter painkillers and is calling ... more to make these drugs safer. , The full report, ...
Breaking Medicine News(10 mins):Health News:SECONDOPINIONS.COM® Introduces Innovative Cloud-Based Medical Imaging Exchange Service for Easy Upload, Access and Sharing Anytime/Anywhere 2Health News:SECONDOPINIONS.COM® Introduces Innovative Cloud-Based Medical Imaging Exchange Service for Easy Upload, Access and Sharing Anytime/Anywhere 3Health News:Body Well Therapy Invites Massage Therapists Nationwide to "Bring Your Own Insurance Clients" 2Health News:Body Well Therapy Invites Massage Therapists Nationwide to "Bring Your Own Insurance Clients" 3Health News:Community Health Center of Snohomish County Reveals the Differences Between Pediatricians and Family Practice Providers 2Health News:Natalie Sharp's Pure Vitality Rx Upgrade - Partnership With Shangri-La Spa and Website Facelift! 2Health News:Consumer Reports Warns Against the Risks of Prescription and Over-The-Counter Painkillers 2Health News:Consumer Reports Warns Against the Risks of Prescription and Over-The-Counter Painkillers 3
... , FARMINGDALE, N.Y., Sept. 2 Misonix, ... invasive ultrasonic medical device technology, which in Europe is used ... health conditions, today announced the restructuring and expansion of its ... created; one for sales and service of the Sonablate(R) 500 ...
... Fox Chase Cancer Center has received an $8 million ... the National Institutes of Health (NCRR/NIH) to expand their ... will support advanced research into the fundamental biological processes ... new treatments. The funds for the grant were made ...
... the total mortality rate from unintentional injury increased in the ... increases were seen in some subgroups analyzed by age, race, ... Hopkins Bloomberg School of Public Health,s Center for Injury Research ... and 64 years old experienced a 230 percent increase in ...
... - Researchers are developing computer models to comb through ... or insurance claims data to automatically classify them based ... to identify the most important causes of injuries so ... of injuries in society," said Mark Lehto, an associate ...
... Washington Post study, approximately 20% of U.S. soldiers returning ... are a substantial number with post-traumatic stress disorder (PTSD), ... has become unacceptable to Army commanders and the soldiers, ... University, however, doctors will now be able to forecast ...
... ... , ... -- Spend one hour with Delaine Anderson, and it,s clear she does not shrink from life,s ... in different parts of the country before that. She even lived seven years in Greece, where ...
Cached Medicine News:Health News:Misonix Restructures and Expands Sales Organization in Europe 2Health News:Misonix Restructures and Expands Sales Organization in Europe 3Health News:Misonix Restructures and Expands Sales Organization in Europe 4Health News:Fox Chase Cancer Center receives $8 million NIH grant to expand laboratory animal research facility 2Health News:Deaths from unintentional injuries increase for many groups 2Health News:New computer models aim to classify, help reduce injury accidents 2Health News:Keeping the suicidal soldier alive 2Health News:Twitter Users Can Follow in Real Time as Local Woman Receives Cyberknife Treatment for Lung Cancer 2Health News:Twitter Users Can Follow in Real Time as Local Woman Receives Cyberknife Treatment for Lung Cancer 3Health News:Twitter Users Can Follow in Real Time as Local Woman Receives Cyberknife Treatment for Lung Cancer 4
... CEQ 8000 is a fully automated genetic ... capillary array with a patented linear polyacrylamide ... applies the voltage program, and analyzes the ... data quality and even customize automated data ...
Basic critical care testing. Measures pH, pCO2, and pO2 from 85 L whole-blood sample....
... parameters from just 95 L of ... as well as any combination of ... Unique technology reduces to a minimum ... on the accuracy of blood gas, ...
348 is fully automated blood gas systems offering a cost-effective solution for critical care testing in settings with low to medium workloads....
Medicine Products: