Navigation Links
Heptares Achieves First Research Milestone in Research Collaboration with Cubist
Date:7/22/2013

WELWYN GARDEN CITY, England and BOSTON, July 22, 2013 /PRNewswire/ --

StaR® Generated to Important GPCR Target Selected by Cubist

Heptares Therapeutics, the leading GPCR drug discovery and development company, announces it has achieved the first research milestone in its collaboration with Cubist Pharmaceuticals, Inc. (NASDAQ: CBST), which was announced in January 2013. The milestone is based on the generation of a stabilised (StaR®) form of a GPCR target selected by Cubist, a key step that will enable the structure of the target to be elucidated and a full structure-based drug design (SBDD) programme to be launched.

Cubist will make an undisclosed payment to Heptares as a result of this research milestone being achieved. Under the terms of the agreement, the collaboration is focusing on up to two GPCR drug targets to be selected by Cubist. Heptares has already received US$5.5 million upfront for the first target, and is eligible to receive up to approximately US$4 million in research funding plus milestones and royalties. Cubist also has the option to nominate a second GPCR target at a later point in the collaboration, which Heptares has agreed to work on according to pre-determined financials. Further terms of the agreement are not disclosed.

To date, Heptares has achieved all scientific milestones in its collaborations on or ahead of schedule, highlighting the power of its GPCR-focused platform. The structural information that Heptares can routinely access for a range of validated drug targets is being used to advance SBDD programmes and to develop lead candidates in multiple disease indications both in house and with partners.

About Heptares Therapeutics

Heptares creates new medicines targeting clinically important, yet historically chall
'/>"/>

SOURCE Heptares Therapeutics
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Heptares Augments Business Development Capabilities in Japan and Other Asian Territories
2. Heptares to Present at Boston Biotech BD and Future Leaders in the Biotech Industry Conferences
3. Heptares to Present at the 6th Annual European Life Sciences CEO Forum (5-6 March)
4. Heptares to Present at 5th CNS Partnering and Deal-Making Conference (13-14 SEPTEMBER)
5. Heptares and UK Medical Research Council Extend GPCR Collaboration
6. MedVantx Achieves Significant Milestone of Managing $1.5B in Prescription Medications and Completes Facilities Expansion While Upgrading To Offer Current Good Manufacturer Practices (cGMP)-level Quality Systems in their Home Delivery Pharmacy
7. Top-line Data Show AcelRx Pharmaceuticals ARX-04 Achieves Primary Endpoint in Dose-Finding Phase 2 Clinical Trial
8. Inovio Pharmaceuticals Universal H1N1 Influenza Vaccine Achieves Protective Immune Responses Comparable to Conventional Vaccine in Phase I Study
9. Relievant Medsystems Achieves Completion of Interim Safety Data Analysis of Intracept in SMART Pivotal Study and Expands Senior Leadership Team
10. Armada Health Care Achieves Full URAC Accreditation
11. Instrumentation Laboratory Achieves Record Sales In 2012
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... CAESAREA, Israel , July 10, 2014 /PRNewswire/ ... Dario™ Diabetes Management Solution, today announced the appointment ... an independent member of its Board of Directors. ... of legal and business experience to LabStyle as ... director, and legal and corporate governance expert. He ...
(Date:7/10/2014)... , July 10, 2014 Decision Resources Group ... of the U.S. Food and Drug Administration,s (FDA) approval ... binder Velphoro, which was approved by the FDA in ... kidney disease (CKD) patients on dialysis. Other ... Nephrology (US) Q2 2014 : ...
(Date:1/15/2014)... /PRNewswire-iReach/ -- ChinaMarketResearchReports.com adds "China Orthopedic Instrument Industry Report, ... (Photo: http://photos.prnewswire.com/prnh/20140115/MN46792 ) Benefiting from ... China,s orthopedic instrument industry has seen ... rising from 3.28 billion yuan in 2006 to 9.85 ...
Breaking Medicine Technology:LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 2LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 3LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 4Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 2Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 3Orthopedic Instrument Industry in China Markets Forecast to 2015 2Orthopedic Instrument Industry in China Markets Forecast to 2015 3
... Solutions, Inc. (OTCQB: VHSLD) announced that it will begin ... Financial Industry Regulatory Authority has approved a change in ... ticker change has gone into effect for the trading ... the "D" will be removed from the ticker symbol ...
... Henry Schein, Inc., (NASDAQ: HSIC ), the ... practitioners, announced today that Stanley M. Bergman, Chairman ... the Company,s Executive Vice President and Chief Financial Officer, will ... on May 4, 2011. The conference is being held at ...
Cached Medicine Technology:Vertical Health Solutions to Begin Doing Business as OnPoint Medical Diagnostics and Announces Completion of Symbol Change 2Henry Schein to Present at Deutsche Bank 36th Annual Health Care Conference 2
(Date:7/10/2014)... (PRWEB) July 10, 2014 A ... program that gets clients off to a great start ... can believe in, has launched a new Eating Disorders ... The new section highlights:, , Different ... Statistic Manual of Mental Disorders (DSM-IV), including anorexia nervosa, ...
(Date:7/10/2014)... not nurture, may play the bigger role in the ... "As is the case in humans, genes matter ... William Hopkins of the Yerkes National Primate Research Center ... journal Current Biology . The findings might ... humans, Hopkins, team said. According to the researchers, ...
(Date:7/10/2014)... -- Men who have a vasectomy may be at ... suggests. But the risk is comparatively small, the ... study said more research is needed to determine if ... study, Harvard researchers analyzed data from more than 49,400 ... in 1986. During that time, 6,023 cases of prostate ...
(Date:7/10/2014)... 200 experts on aggression, who research issues ranging from ... 21st World Meeting of the International Society for Research ... 15-19. , Georgia State University is hosting the prestigious ... alternating continents. , "We are excited to be bringing ... which will help produce fresh ideas about the causes, ...
(Date:7/10/2014)... The U.S. Department of Health and Human Services (HHS) ... Case Medical Center Seidman Cancer Center totaling $4.7 million ... care for patients with complex cancer. , Titled ... model developed at UH to enhance care for adult ... need for high health care utilization. , ...
Breaking Medicine News(10 mins):Health News:Latest A Forever Recovery Launches Eating Disorders Section on Website 2Health News:Like Humans, Chimps' Smarts May Rely on Genes 2Health News:Study Links Vasectomy to Aggressive Prostate Cancer 2Health News:Study Links Vasectomy to Aggressive Prostate Cancer 3Health News:Georgia State hosts national conference on aggression 2Health News:Georgia State hosts national conference on aggression 3Health News:UH Case Medical Center awarded $4.7 million grant from HHS 2Health News:UH Case Medical Center awarded $4.7 million grant from HHS 3
... to smoke, researchers say , WEDNESDAY, Sept. 9 (HealthDay News) ... cigarettes, "tricks" the brain into creating memory associations between environmental ... smokers miss lighting up when they are in a bar ... at Baylor College of Medicine are in the Sept. 10 ...
... , , NEW YORK, ... zooming by, it might just be one of the Vespa LX 50 ... are adding to their autumn Breast Cancer Awareness initiatives. Through a partnership ... Breast Cancer for Life: The Power of 15," Vespa USA ( ...
... , , , PRINCETON, ... from around the globe will converge at Las Vegas, Mandalay ... Conference & Expo. , , Produced ... will focus on "Thinking Forward - The Power of the ...
... , , , ... awarded $7,500 in grants to 15 nonprofit organizations in Pennsylvania and ... grants were awarded through Highmark,s Employee Volunteer Grant Program, which reinforces ... to help local organizations carry out their missions in the community. ...
... , , WASHINGTON, Sept. 9 ... joining Pioneering Healthier Communities (PHC), its signature initiative that brings together ... through environmental and policy change. PHC is funded through a ... , , Since its inception in ...
... VILLAGE, Nev., Sept. 9 PDL BioPharma, Inc. (PDL) (Nasdaq: ... president and chief executive officer, will present at the BioCentury NewsMakers ... September 16, 2009 at 11:00 a.m. Eastern Time. , , ... the conference call, go to the company,s website at ...
Cached Medicine News:Health News:Nicotine Plays Tricks on Brain: Study 2Health News:Vespa Pink Campaign Supports Fight Against Breast Cancer 2Health News:Vespa Pink Campaign Supports Fight Against Breast Cancer 3Health News:Vespa Pink Campaign Supports Fight Against Breast Cancer 4Health News:Vespa Pink Campaign Supports Fight Against Breast Cancer 5Health News:Global Gathering for Contact Center Professionals to Focus On 'Thinking Forward - The Power of the Customer Experience' at ICMI's Annual Call Center Exhibition Conference and Expo, Oct. 5-9 in Las Vegas 2Health News:Global Gathering for Contact Center Professionals to Focus On 'Thinking Forward - The Power of the Customer Experience' at ICMI's Annual Call Center Exhibition Conference and Expo, Oct. 5-9 in Las Vegas 3Health News:Highmark Inc. Awards $7,500 to 15 Pennsylvania Nonprofit Organizations 2Health News:Highmark Inc. Awards $7,500 to 15 Pennsylvania Nonprofit Organizations 3Health News:Highmark Inc. Awards $7,500 to 15 Pennsylvania Nonprofit Organizations 4Health News:YMCA Expands Pioneering Healthier Communities Initiative to Lead Healthy Change in Communities Nationwide 2Health News:YMCA Expands Pioneering Healthier Communities Initiative to Lead Healthy Change in Communities Nationwide 3Health News:YMCA Expands Pioneering Healthier Communities Initiative to Lead Healthy Change in Communities Nationwide 4Health News:YMCA Expands Pioneering Healthier Communities Initiative to Lead Healthy Change in Communities Nationwide 5
Bone Curette, 160 mm...
Bone Currettes...
London Endocervical Curette is a stainless-steel curette for obtaining endocervical samples with minimal effort....
...
Medicine Products: