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Hemophilia Pipeline Overview - Once-a-week prophylaxis may soon become a reality
Date:12/13/2012

recombinant PEGylated factor IX; Baxter)

CSL654 (rFIX-albumin fusion; CSL Behring)

BIIB 029 (rFIXFc; Biogen Idec)

NN7999 (rFIX, glycoPEGylated; Novo Nordisk)

Clinical and commercial attractiveness for key hemophilia B pipeline products

Bibliography

Journal articles and online sources

Appendix

Methodology

Datamonitor drug assessment for clinical and commercial attractiveness

TABLES

Table: Clinical pipeline key drugs for hemophilia A and B, November 2012

Table: Kogenate FS (recombinant Factor VIII; Bayer) – drug profile, 2012

Table: Kogenate FS (recombinant Factor VIII; Bayer) – drug profile, 2012

Table: Kogenate FS (rFVIII; Bayer) and BeneFIX (rFIX; Pfizer) vs the target product profile in previously treated patients, 2012

Table: Key events in the clinical development of NN7008 (turoctocog alfa; Novo Nordisk), 2012

Table: Key events in the clinical development of BIIB 031 (rFVIIIFc; Biogen Idec), 2012

Table: Key events for the clinical development of NN7088 (Novo Nordisk), 2012

Table: Key events for the clinical development of BAY-94-9027 (Bayer), 2012

Table: Key events for the clinical development of BAX 326 (Baxter), 2012

Table: Key events for the clinical development of CSL654 (CSL Behring), 2012

Table: Key events for the clinical development of BIIB 029 (rFIXFc; Biogen Idec), 2012

Table: Key events for the clinical development of NN7999 (Novo Nordisk), 2012

FIGURES

Figure: Clinical and commercial attractiveness for key hemophilia A pipeline drugs vs comparator Kogenate FS (rFVIII; Bayer), 2012

Figure: Breakdown of clinical and commercial attractiveness attributes for key hemophilia A pipeline drugs, 2012

Figure: Launch timeline for key hemophilia A pipeline drugs, 2012

Figure: Clinical and commercial attractiveness for key hemophilia B pipeline drugs vs comparator B
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