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HemoShear Announces Advancement of Predictive Drug Safety Systems
Date:7/18/2013

rat system has enabled significant progress in developing a human liver surrogate system, which is currently being validated with known drugs.  HemoShear has already validated a physiologically accurate vascular system and vascular disease conditions.  By gaining access to our liver and vascular systems and diseases, our pharmaceutical partners can save millions of dollars by avoiding drugs that are doomed to fail, while redirecting precious resources to drug candidates that are more likely to succeed in humans," said Brian Wamhoff, Ph.D., HemoShear's co-founder and Vice President of R&D.

HemoShear's publication may be found at the following address:   
http://www.ncbi.nlm.nih.gov/pubmed/23485712

Dash A, Simmers MB, Deering TG, Berry DJ, Feaver RE, Hastings NE, Pruett TL, Lecluyse EL, Blackman BR, Wamhoff BR. Hemodynamic Flow Improves Rat Hepatocyte Morphology, Function and Metabolic Activity in vitro. Am J Physiol Cell Physiol. 2013 Mar 13 [Epub ahead of print]

About HemoShear, LLC

By applying physiologically accurate hemodynamics and biological transport to primary cell cultures, HemoShear creates human-relevant systems that accurately replicate the biology of organ systems and diseases for applications throughout drug discovery and development. Working in strategic partnerships with pharmaceutical, biotechnology and medical device companies, HemoShear generates meaningful data to increase confidence in decision-making, reduce risk of costly failures and identify efficacious therapies. HemoShear's science leads to new medicines and improves human health.  

For information about HemoShear, please visit www.hemoshear.com.


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SOURCE HemoShear, LLC
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