Navigation Links
HemaQuest Pharmaceuticals, Inc. Presents Promising Clinical Results at 52nd Annual Meeting of the American Society of Hematology (ASH)
Date:12/7/2010

evidence of the safety and potential therapeutic activity of HQK-1001 in patients with sickle cell disease and beta thalassemia intermedia. The fetal hemoglobin induction observed in both of the clinical trials is important, given its key role in ameliorating these diseases. Based on these promising clinical results, we plan to initiate a clinical trial testing higher dose levels and longer duration of therapy to more fully characterize the therapeutic potential of HQK-1001 in sickle cell disease."

ABOUT HQK-1001 HQK-1001 belongs to a class of compounds originally discovered at Boston University School of Medicine. These compounds, designated as Short Chain Fatty Acid Derivatives (SCFADs), have been shown to stimulate fetal hemoglobin expression and red blood cell production in the laboratory and in small clinical trials in patients with hemoglobin disorders, including sickle cell disease and beta thalassemia.  Increased fetal hemoglobin production in red blood cells was shown to ameliorate the outcome of patients with these diseases. HQK-1001 is an orally administered SCFAD, which has shown an excellent safety profile and biologic effects on fetal hemoglobin induction and red blood cell production in the laboratory, relevant animal models, and in clinical trials carried out in healthy human subjects as well as patients with sickle cell disease and beta thalassemia. Additionally, the compound has received Orphan Drug Designation in the United States and Europe for both sickle cell disease and beta thalassemia.

ABOUT SICKLE CELL DISEASE AND BETA THALASSEMIASickle cell disease is a genetic blood disorder that affects approximately 80,000 patients in the U.S., and is characterized by production of an abnormal beta hemoglobin chain of adult hemoglobin, which results in distorted, rigid sickle red blood cells, which block blood vessels, causing lack of oxygen to tissues, acute episodes of pain (pain crises), lung injury (acute chest syndrome), a
'/>"/>

SOURCE HemaQuest Pharmaceuticals
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. HemaQuest Announces Appointment of New Executive Management Team; Company Establishes Headquarters in San Diego
2. HemaQuest Pharmaceuticals Raises Additional $4M to Bring Total to $16M in Series B Financing
3. Aires Pharmaceuticals, Inc. Completes $20M Equity Financing and Signs an Option Agreement with a Major Pharmaceutical Company
4. Omthera Pharmaceuticals, Inc. to Present at the Lazard Capital Markets 7th Annual Healthcare Conference
5. Keryx Biopharmaceuticals, Inc. Announces Third Quarter 2010 Financial Results
6. DUSA Pharmaceuticals, Inc.® to Host Third Quarter 2010 Corporate Highlights and Financial Results Conference Call
7. Pfizer Commences Tender Offer for All Outstanding Shares of King Pharmaceuticals, Inc.
8. Anadys Pharmaceuticals, Inc. Announces Proposed Public Offering of Common Stock
9. Auxilium Pharmaceuticals, Inc. Announces Issuance of Patent for Clostridial Collagenase
10. Auxilium Pharmaceuticals, Inc. Announces Initiation of XIAFLEX® Phase III Studies for Peyronies Disease
11. Star Scientific Comments on Roskamp Institutes Plans to Conduct Human Alzheimers Clinical Trials Using a Compound (RCP-006) Developed by Rock Creek Pharmaceuticals, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... 2014  eRelevance Corporation ( www.erelevancecorp.com ), a ... it has completed integration with Nextech, a popular ... and Dermatology practices. "Integration allows our ... practices using Nextech," stated Bob Fabbio , ... from the EMR we are able to automatically ...
(Date:8/21/2014)... - Eisai Limited is pleased to support the Canadian Epilepsy ... available in Canada . The comic book, ... children and their parents about epilepsy, the most common neurological ... 300,000 Canadians. Eisai is guided by a corporate philosophy known ... patient is central – there was a need within the ...
(Date:8/21/2014)... Aug. 21, 2014 /PRNewswire-iReach/ -- Inc. ... for the third straight year, No. 349 in ... exclusive ranking of the nation,s fastest-growing private companies. ... the most important segment of the economy—America,s independent ... Domino,s Pizza, LinkedIn, Zillow, and many other well-known ...
Breaking Medicine Technology:eRelevance Corporation Integrates with Nextech Electronic Medical Records 2Eisai Pleased to Support Canadian Epilepsy Alliance Comic Book that Teaches Children About Epilepsy 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 3
... Corporation (NYSE: POL ), a premier global ... showcase a growing range of specialty healthcare solutions at ... With more than 200 participating companies and 6,000 ... medical device manufacturing sector in China.   ...
... Sept. 6, 2011 Isis Pharmaceuticals, Inc. (Nasdaq: ... Open-Label Extension Study presented at ESCWhen: , Wednesday, September 07, ... www.isispharm.comHow: , Live on the Internet.  Simply log onto our ... during the live event, a replay of the webcast will ...
Cached Medicine Technology:PolyOne's Healthcare Solutions and Distribution Network Showcased at Medtec China 2PolyOne's Healthcare Solutions and Distribution Network Showcased at Medtec China 3
(Date:8/23/2014)... 2014 "When men sit down to ... with the dirty water inside the bowl, the interior ... one of two inventors from Naugatuck, and Bridgeport, Conn. ... this protective device." , They developed the IPSAFE to ... the water, bowl and seat. This minimizes exposure to ...
(Date:8/23/2014)... GBI Research, the leading business intelligence provider, has ... Developed Markets to 2020 - New and Late-Stage Four-Factor ... in-depth analysis of the critical care market in the ... The report provides an estimation of market size for ... critical care indications that are being treated using the ...
(Date:8/23/2014)... 2014 Dealing with a drug or alcohol ... the addict is a child. Adolescent addiction has been an ... time, but a new helpline is now providing a valuable ... to find a real addiction recovery center. , The Troubled ... impact in the community. By calling (404) 975-2762, parents and ...
(Date:8/22/2014)... Search Engine Optimization is needed ... of search engines and get more audience and ... compared many Linux hosting suppliers and announced that ... most recommended Linux hosting suppliers for webmasters from ... buy high quality Linux hosting (including VPS and ...
(Date:8/22/2014)... Park City, UT (PRWEB) August 22, 2014 ... Solution, published a new guide on Account-Based Health Plans. ... health plans (ABHPs) as a strategy to lower the ... the different types of medical spending accounts, however, can ... easy-to-understand comparison chart to learn the four main types ...
Breaking Medicine News(10 mins):Health News:Critical Care Therapeutics in Major Developed Markets to 2020 | Researchmoz 2Health News:Critical Care Therapeutics in Major Developed Markets to 2020 | Researchmoz 3Health News:Atlanta’s New Troubled Teen Helpline Is Making a Difference in the Community 2Health News:Top10BestSEOHosting.com Announces Best Cheap Hosting Suppliers Of This Summer 2
... diseased human bone marrow to become embryonic-like stem cells, ... for observing the onset of the blood cancer leukemia ... reprogramming of blood cells obtained from a patient with ... Slukvin, who directed a study aimed at generating all-purpose ...
... By Steven Reinberg HealthDay Reporter , THURSDAY, Feb. 3 ... the U.S. population, they account for 50.3 percent of all diagnosed ... of HIV diagnosis among black men is eight times that of ... of whites, finds a new analysis of data from 37 ...
... -- About 340,000 cancer cases in the United States could ... diet, got regular exercise and limited their alcohol intake, according ... of lifestyle changes could lead to significant reductions in particularly ... year), stomach (47 percent fewer) and colon (45 percent fewer). ...
... , THURSDAY, Feb. 3 (HealthDay News) -- If ... the Super Bowl, there are some simple things you can ... next day, says an expert. Gastroenterologist Dr. Cynthia Yoshida ... every alcoholic beverage with a non-alcoholic drink. Caffeine-free, non-carbonated drinks, ...
... Jenifer Goodwin HealthDay Reporter , THURSDAY, Feb. ... to lose weight, gastric bypass surgery seems to help ... and appearance, a new study suggests. Obesity is ... including heart failure, atrial fibrillation (an abnormal heart rhythm) ...
... HealthDay Reporter , THURSDAY, Feb. 3 (HealthDay News) -- ... appear to lose mobility faster than men, new research reveals. ... peripheral arteries, usually those in the legs and pelvis. The ... leg or hip muscles when walking or climbing stairs -- ...
Cached Medicine News:Health News:New induced stem cells may unmask cancer at earliest stage 2Health News: Burden of HIV Highest for Blacks, CDC Reports 2Health News: Burden of HIV Highest for Blacks, CDC Reports 3Health News:Healthier Lifestyles May Prevent 340,000 U.S. Cancers a Year: Study 2Health News:Weight-Loss Surgery May 'Remodel' Heart 2Health News:Weight-Loss Surgery May 'Remodel' Heart 3Health News:Narrowed Leg Arteries Disable Women Faster Than Men: Study 2Health News:Narrowed Leg Arteries Disable Women Faster Than Men: Study 3
The Astigmatome makes precise and accurate cuts for astigmatism correction simply and safely....
The Astigmatome makes precise and accurate cuts for astigmatism correction simply and safely. The procedure can be done in the office under topical anesthesia. Template Set 10mm Set. Includes 0 - 360...
... Medtronic presents the Streamline family of temporary ... taken the gold standard in temporary pacing ... make them easy to use and less ... Temporary Pacing Leads are designed to provide ...
... Carpentier-Edwards Classic annuloplasty rings have ... choice for more than 30 ... restore the anatomical size and ... to help prevent recurrent dilatation. ...
Medicine Products: