Navigation Links
Healthscope to commercially launch Circadian's Cancers of Unknown Primary Diagnostic Test
Date:6/26/2012

eptors, primarily VEGFR-2, the multi-billion dollar cancer therapeutic slows tumour growth by inhibiting blood vessel recruitment into the tumour, effectively starving tumours of essential nutrients and oxygen required for growth. However after a short period of time tumors can begin to grow again in the presence of Avastin®. Avastin® is approved by the US FDA in the following indications: metastatic colorectal cancer, non-squamous-cell lung cancer, metastatic breast cancer, glioblastoma, and metastatic renal cell carcinoma.

The angiogenic receptor VEGFR-2 can also be stimulated by VEGF-C and hence an inhibitor such as VGX-100, a key therapeutic in Circadian's portfolio, can produce greater blockade of this receptor pathway. As such, VGX-100 has the potential to block blood vessel growth in tumours which grow in the presence of Avastin® therapy and hence may completely shut down angiogenesis (the growth of blood vessels) mediated by VEGFR-2.

VEGF-C along with the molecule VEGF-D are also the only known proteins to bind and activate VEGFR-3 which drives lymphatic vessel and tumour-associated blood vessel growth. Inhibitors of VEGF-C thus have therapeutic potential to inhibit not only primary tumour growth through their anti-angiogenic activities, but to also inhibit tumour spread or metastasis via the lymphatic vessels - a mechanism of tumour dissemination that is often the deadliest aspect of many tumour types and a mechanism that is not effectively blocked by anti-VEGF-A or anti-VEGFR-2 therapeutics.

Inherent risks of Investment in Biotechnology Companies

There are a number of inherent risks associated with the development of pharmaceutical products to a marketable stage. The lengthy clinical trial process is designed to assess the safety and efficacy of a drug prior to commercialisation and a significant proportion of drugs fail one or both of these criteria. Other risks include uncertainty of patent protection and propri
'/>"/>

SOURCE Circadian Technologies Limited
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. PeriGen, Inc. Launches Consumer Safety Campaign to Raise Awareness of Dangerous Birth Complication
2. Varian X-Ray Products Business Launches On-Line Product Finder for Customers
3. Frost & Sullivan: Launch of New Classes of Oral Antidiabetic Drugs by 2014 will Uplift Prospects for the European Diabetes Therapeutics Market
4. Konica Minolta Sensing America Launches Spanish Website in Support of Growing Demand In Latin American Countries
5. Nouveau Life Pharmaceuticals (NOUV) to Launch Affiliate Sales Program
6. The Michael J. Fox Foundation Launches The $14 Million-Edmond J. Safra Core Programs for PD Research
7. Lifescript Launches New Online Asthma Health Center
8. AUA Foundation Launches Campaign to Address Stigma of Overactive Bladder
9. Office Star to Launch Safety Campaign at The Mobility Roadshow
10. Smith & Nephew launches two plating systems for foot and ankle surgeons at AOFAS annual meeting in San Diego
11. Lilly Diabetes Launches 8th Annual Diabetes Summer Camp Tour With Olympian Kris Freeman
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... July 23, 2014  The management team at ... will hold a conference call on July 31, ... quarter ended June 30, 2014.  The call details ... , 8:30 am EDTDial-in numbers: , Toll free: ... 317-0790Webcast (live & archive): , www.columbialabs.com , ...
(Date:7/23/2014)... -- Global healthcare company GSK reports Q2 ... increased price competition and supply disruptions to its Consumer ... points out that the company is very much in transition, ... confident about long-term prospects as well as the investments ... Simon Dingemans adds that the company is ...
(Date:7/23/2014)... 23, 2014 Research and Markets ... "Prepackaged Medical Kits and Trays - Global Strategic ... http://photos.prnewswire.com/prnh/20130307/600769 ... Medical Kits and Trays in US$ Thousands by ... Custom Trays, Custom Basin Kits, Custom Ob/Gyn Kits, ...
Breaking Medicine Technology:Columbia Laboratories to Discuss Second Quarter 2014 Financial Results on July 31st Conference Call 2Prepackaged Medical Kits and Trays - Global Strategic Business Report: Updated 2014 Report 2
... LOS ANGELES, May 16, 2011 UBM Canon,s medical ... content topics for the remainder of 2011. ... pulled together an exciting list of comprehensive content topics ... design to outsourcing," stated Rich Nass, Director of Content ...
... 16, 2011 During Older Americans Month, the ... connect with their pharmacist to gain better knowledge of ... As the most accessible health care provider and the ... the issues that arise due to medications and age. ...
Cached Medicine Technology:UBM Canon Medical Device Content Team Announces Upcoming Virtual Event Content Topics 2UBM Canon Medical Device Content Team Announces Upcoming Virtual Event Content Topics 3APhA Encourages Seniors to Connect with Their Pharmacist to Increase Wellness and Medication Knowledge 2APhA Encourages Seniors to Connect with Their Pharmacist to Increase Wellness and Medication Knowledge 3
(Date:7/23/2014)... MA (PRWEB) July 23, 2014 ... technologies, the leasing and financing company LeaseQ announced ... the server based software sector, they still see ... , To learn more about technology equipment ... Founder and CEO of LeaseQ was quoted as ...
(Date:7/23/2014)... 23, 2014 According to a new ... Form Factor (Integrated Circuit IP, SOC IP), Design Architecture ... Geography and Verification IP - Forecast & Analysis to ... expected to grow at a CAGR of 12.6% from ... , Browse more than 76 market data tables with ...
(Date:7/23/2014)... Splashtop , a leader ... it has joined the RSA Ready Technology Partner ... and RSA SecurID® multi-factor authentication solution from RSA, ... , Splashtop also announced that leading Japanese Insurance ... Enterprise, the industry’s only on-premise remote access solution. ...
(Date:7/23/2014)... The Centers for Disease Control and Prevention ... from 2010 to 2012. Formerly known as “the nation’s ... access to some of the strongest opiates, such as Oxycontin, ... enforcement launched an initiative to crack down on these rampant ... 65 that existed in the state just a few years ...
(Date:7/23/2014)... first time to call for better screening of psoriatic ... the condition. , Psoriatic arthritis (PsA) causes painful joint ... untreated. , PsA tends to affect people with the ... and affects approximately two per cent of people in ... on to develop PsA usually within ten years ...
Breaking Medicine News(10 mins):Health News:LeaseQ Announces That Although Software Investment Remains Sluggish, Technology Equipment Leasing Demand Remains Robust 2Health News:LeaseQ Announces That Although Software Investment Remains Sluggish, Technology Equipment Leasing Demand Remains Robust 3Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 2Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 3Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 4Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 5Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 6Health News:Splashtop Joins RSA® Ready Technology Partner Program; Announces Adoption by Leading Japan Insurance Group Nissei Asset Management 2Health News:Splashtop Joins RSA® Ready Technology Partner Program; Announces Adoption by Leading Japan Insurance Group Nissei Asset Management 3Health News:Florida’s Crackdown on Pill Mills Has Led to Rise in Popularity of Synthetic Drugs; Suncoast Rehab Educates on Dangers of These Drugs in Adolescents 2Health News:Florida’s Crackdown on Pill Mills Has Led to Rise in Popularity of Synthetic Drugs; Suncoast Rehab Educates on Dangers of These Drugs in Adolescents 3Health News:Florida’s Crackdown on Pill Mills Has Led to Rise in Popularity of Synthetic Drugs; Suncoast Rehab Educates on Dangers of These Drugs in Adolescents 4Health News:Psoriatic arthritis patients need better screening, warns panel of experts 2
... says that a serving or two of dark or bitter ... comes as a breath of fresh “sweet” air from Swiss ... at Zurich's University hospital. They investigated and found after tests ... cocoa content (75 per cent) improved their blood circulation "significantly". ...
... Executive Director Peter Ellis has revealed that a version of the ... dysfunction market is much larger when compared to that of men, ... pill for that, according to Ellis. The desire, arousal and pain ... the pill, which will make it all the more difficult to ...
... flight attendants working for a National European Airline from ... they rate their health as poor when they have ... to the other women who are working with the ... attention, being proposed, ogled at, subjected to offensive remarks ...
... brandy per day reportedly has a similar antioxidant potential which ... belonging to the Monash University. This does not mean that ... can continue along with drinking brandy. ,Red ... arteries are de-sludged by its consumption in addition to it ...
... at risk for high blood pressure, heart disease and ... current issue of the American Journal of Preventive Medicine. ... blood pressure, or hypertension, generally consume less sodium than ... than recommended levels, according to lead researcher Umed Ajani, ...
... The National Institutes of Health (NIH) has revealed that the ... the youngsters in the US. There has however been an ... purposes. The University of Michigan conducted the 2005 Monitoring the ... overall results were good. , ,It found that cigarette ...
Cached Medicine News:Health News:Americans Consume Far Too Much Salt and Sodium 2Health News:Drug Use On The Decline Among US Youth 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: