Health Canada Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regim... (TRIPLA with caution in patients with a h...)

HOME >> MEDICINE >> TECHNOLOGY

Health Canada Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for HIV

Date:10/17/2007

TRIPLA with caution in patients with a history of seizures. Convulsions have been observed in patients receiving efavirenz, generally in the presence of known medical history of seizures.

Redistribution/accumulation of body fat has been observed in patients receiving antiretroviral therapy.

Immune reconstitution syndrome has been reported in patients treated with combination antiretroviral therapy, including the components of ATRIPLA.

Saquinavir should not be used as the only protease inhibitor in combination with ATRIPLA.

Coadministration of ATRIPLA and atazanavir is not recommended due to concerns regarding decreased atazanavir concentrations. Atazanavir and lopinavir/ritonavir have been shown to increase tenofovir concentrations. Patients on atazanavir or lopinavir/ritonavir plus ATRIPLA should be monitored for tenofovir-associated adverse events. ATRIPLA should be discontinued in patients who develop tenofovir-associated adverse events.

Coadministration of ATRIPLA with didanosine should be undertaken with caution. Patients receiving this combination should be monitored closely for didanosine-associated adverse events. See Full Prescribing Information for complete list of drug-drug interactions.

In Study 934, the most frequently reported grades 2-4 adverse events through 48 weeks in patients receiving efavirenz + emtricitabine + tenofovir DF were dizziness (8%), nausea (8%), diarrhea (7%), fatigue (7%), headache (5%), rash (5%), sinusitis (4%), depression (4%), insomnia (4%), and abnormal dreams (4%).

The dose of ATRIPLA is one tablet (containing 600 mg of efavirenz, 200 mg of emtricitabine, and 300 mg of tenofovir DF) once daily taken orally on an empty stomach. Dosing at bedtime may improve the tolerability of nervous system symptoms. ATRIPLA is not recommended for use in patients <18 years of age.

For complete prescribing information for ATRIPLA, visit http://www.atr
'/>"/>

SOURCE Bristol-Myers Squibb Company
Copyright©2007 PR Newswire.
All rights reserved

1

GOOD

Page: 1 2 3 4 5 6 7 8 9
Related medicine technology :

1. Controlling the Spread of Healthcare Associated Methicillin Resistant Staphylococcus aureus Requires Active Surveillance
2. Largest National U.S. Healthcare Facility MRSA Study Reveals Infection Rates Eight Times Greater Than Previous Estimates
3. Nationwide MRSA Prevalence Study to Demonstrate Full Scope of Superbug Threat Facing U.S. Healthcare Facilities and Patients
4. Arterial Plaque Significantly Reduced in Women Age 50-59 Taking Hormones, Says New Analysis of Womens Health Initiative Data
5. Data Showing that ReGens Colostrinin Supports Healthy Cognitive Function Presented at the 2007 International Congress on Natural Medicine in Australia
6. Antidepressant Use May Boost Fracture Risk, From Harvard Womens Health Watch
7. FDLI 50th Annual Meeting Heralds New ERA in Healthcare Innovations, FDA Regulations
8. New Data On the Probiotic Strain Bifantis Shows Anti-Inflammatory Properties and Increased Health Benefits
9. Actilyse (alteplase) Recommended by National Institute for Health and Clinical Excellence for Treatment of Acute Ischaemic Stroke
10. Genzyme and Bayer HealthCare Announce Detailed Interim Two-Year Alemtuzumab in Multiple Sclerosis Data Presented at AAN
11. Eighty-one Percent of U.S. Adults say that Birth Control Pills and Procedures Should Be Covered by Health Insurance

Post Your Comments:

(Date:5/21/2013)... 21, 2013 STAAR Surgical Company (NASDAQ: ... of minimally invasive ophthalmic products, today announced that it ... the Company,s recent financial results and business developments with ... present at the 38 th Annual Deutsche Bank ... at the Westin Waterfront Hotel on Wednesday, May 29, ...

(Date:5/20/2013)... , May 21, 2013 ... Assembly, where world,s health ministers gather to address the ... Mental and neurological disorders (MNDs) affect 700 million ... non-communicable disease (NCD) burden ,Do You Mind?, ... the role each can play to collectively address MNDs ...

(Date:5/20/2013)... GLENWOOD, Ill. , May 20, 2013 ... leader in personal and environmental radiation measurement and monitoring, ... accessories, announced today that its Board of Directors declared, ... quarterly cash dividend of $0.55 per share for the ... paid on July 3, 2013, to shareholders of record ...

Breaking Medicine Technology:STAAR Surgical To Present At Upcoming Investor Conferences 2 Research-based Pharmaceutical Industry Launches 'Do You Mind?' Campaign to Fight Mental and Neurological Disorders 2 Landauer, Inc. Declares Regular Cash Dividend 2

[0] STAAR Surgical To Present At Upcoming Investor Conferences [0] Research-based Pharmaceutical Industry Launches 'Do You Mind?' Campaign to Fight Mental and Neurological Disorders [0] Landauer, Inc. Declares Regular Cash Dividend

... CHAPEL HILL, N.C., July 22, 2011 The oncology ... new pharmaceutical product investment and launches as next generation ... more new targeted oncology products finding success, organizations in ... that is pushing them to rethink the factors that ...

... ST. LOUIS, July 22, 2011 United Seating & ... has finalized a transaction with Central Kentucky Mobility (CKM) to ... will continue services for Lexington, Louisville, as well as central, ... Kentucky Mobility,s rehab team strengthens our position within a core ...

Cached Medicine Technology:Success Factors and Failure Points for Oncology New Product Launches 2

Success Factors and Failure Points for Oncology New Product Launches United Seating & Mobility Reaches Agreement to Acquire Central Kentucky Mobility

(Date:5/21/2013)... HealthDay Reporter , , TUESDAY, May 21 (HealthDay News) -- ... some of the changes brought about by the disorder ... New research has found that people with diabetes who ... risk of having a severe low blood sugar (hypoglycemia) ... people with diabetes who aren,t depressed. "Depression ...

(Date:5/21/2013)... Brussels proposes to include on tobacco packages in order ... on smokers because they only find some of them ... improve the efficacy of its anti-smoking campaigns, it should ... stronger emotional impact., These are some of the conclusions ... and Psychological Treatment at the University of Granada by ...

(Date:5/21/2013)... American Philosophical Society (APS) has awarded New York University ... Award in recognition of his "pioneering work on the ... York University,s Center for Neural Science, is the second ... three yearsJoseph LeDoux received the honor in 2011 in ... of emotional learning, particularly fear learning, and fear memory." ...

(Date:5/21/2013)... 2013 The team at Comfort &Harmony™, a ... new mom pick a nursing pillow. , Nursing pillows ... mom and baby. , In a nursing pillow, ... added features. Designers at Comfort & Harmony, kept this ... SHAPE: The nursing pillow needs to fit a mom’s body ...

(Date:5/21/2013)... Representatives with Hammerhead Bicycles announced today that their re-launched ... has achieved its overall goal of becoming a standalone brand. ... Hammerhead Bicycles from a house brand to a standalone bike ... explained that the bike shop will go forward as ... things 29er and 650b. , “The bike shop ...

Breaking Medicine News(10 mins):Health News:Depression May Raise Low Blood Sugar Risk in Diabetics 2 Health News:Depression May Raise Low Blood Sugar Risk in Diabetics 3 Health News:Warning images for cigarette packs proposed by Europe do not make enough emotional impact 2 Health News:NYU's Movshon receives Lashley Award for his research on the neuroscience of vision 2 Health News:Comfort and Harmony™ Shares Tips on What to Look for in a Nursing Pillow 2 Health News:Comfort and Harmony™ Shares Tips on What to Look for in a Nursing Pillow 3 Health News:Hammerhead Bicycles Now a Standalone Brand 2

[0] Depression May Raise Low Blood Sugar Risk in Diabetics [0] Warning images for cigarette packs proposed by Europe do not make enough emotional impact [0] NYU's Movshon receives Lashley Award for his research on the neuroscience of vision [0] Comfort and Harmony™ Shares Tips on What to Look for in a Nursing Pillow [0] Hammerhead Bicycles Now a Standalone Brand

... Program Initiated in Europe SEATTLE, May 7 Cell ... accomplishments and financial results for the quarter ended March ... 2009 was to initiate and complete the NDA submission ... cost cutting efforts and raised much needed operating capital ...

... Children Under the Age of Five Are Food InsecureCHICAGO, May 7 ... hunger in 26 states in the U.S., according to a new ... in young children is 33 percent higher than in U.S. adults, ... Insecurity in the United States : 2005 -- ...

... Scheduled for May 7, 2009 at 10:30 a.m. PT ... (Nasdaq: ENSG ), the parent company of the ... living companies, today reported record results for the first quarter ... Quarter-over-Quarter Highlights Include: , , ...

... Inc. (Nasdaq: YDNT ) today announced that ... $0.04 per share, payable June 15, 2009 to all ... manufactures, and markets supplies and equipment used by dentists, ... offering includes disposable and metal prophy angles, prophy cups ...

... US Senate recently introduced legislation that would increase access ... the need for a physician,s referral or certification of ... direct access is authorized, says the American Physical Therapy ... Physical Therapists Act (S 950), introduced by Senators Blanche ...

... May 6 The Commander of the 125,000-member Indiana ... "find the courage to speak and act plainly on ... Sailors, Children,s Home at Knightstown."Ralph Tolan called on legislators ... for closing the home" which, under plans announced by ...

Cell Therapeutics Reports 76% Decrease in First Quarter 2009 Net Loss Attributable to Common Shareholders; Completion of Pixantrone NDA Submission on Track for Second Quarter 2009 One in Six Young Children Live at Risk of Hunger in 26 U.S. States According to New Feeding America Report The Ensign Group Reports First Quarter 2009 Earnings of $0.38 per Share; Reaffirms 2009 Guidance Young Innovations Inc. Board of Directors Declares Quarterly Dividend Senate Introduces Legislation to Increase Access to Physical Therapist Services Legion Demands 'Courage' From Legislators in Battle Over Children's Home

... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...

... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...

... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...

Medicine Products:

PBG, Urine Quantitative Paxil, Urine Partial Thromboplastin Time with Reflex to PTT 1:1 Mix Paroxysmal Nocturnal Hemoglobinuria Profile-WBC