Navigation Links
Harvard Medical School-Partners HealthCare Center for Genetics and Genomics Successfully Completes Evaluation of AutoGenomics 2C9-VKORC1 Panel to Assess Warfarin Sensitivity
Date:8/19/2007

CARLSBAD, Calif., Aug. 17 /PRNewswire/ -- AutoGenomics, a leader in developing automated molecular testing solutions, announced today that its CYP450 2C9-VKORC1 panel that it submitted to the FDA for 510(k) clearance late last year, has now been evaluated by the Harvard Medical School-Partners HealthCare Center for Genetics and Genomics (HPCGG).

Warfarin (also called Coumadin) is a drug prescribed to help prevent blood clots. With more than 2 million prescriptions per year, one of the side effects of the drug is an increased risk of bleeding. The FDA re-labeled yesterday the warfarin package insert recommending the testing of multiple genetic variants in two genes namely 2C9 and VKORC1 for safer drug dosing.

"We have completed a successful evaluation of the INFINITI 2C9-VKORC1 panel which has the potential to optimize warfarin dosing and lower the risk of bleeding complications" said Dr. Raju Kucherlapati, Scientific Director of the Harvard Medical School-Partners HealthCare Center for Genetics and Genomics (HPCGG) in Cambridge, Massachusetts. HPCGG is coordinating the "CReating an Optimal Warfarin Nomogram" (CROWN) Trial which is a prospective dosing study utilizing genetic testing to determine the optimal warfarin dose and how this information can be used for clinical care.

"We are pleased to see that through the re-labeling of the warfarin package insert, the FDA has recognized that patients with certain genetic variants may benefit from lower initial dosage thus reducing the risk of major bleeding events" said Ram Vairavan, Senior Vice President at AutoGenomics. He further said "Our expanded panel of genetic variants mentioned in the package insert encompassing African, Asian and other ethnic groups enables same day dosing on our automated multiplexing platform."

About AutoGenomics

AutoGenomics Inc., a privately held company based in Carlsbad, CA, has developed the first automated, microarray based multiplexing diagnostic pla
'/>"/>

SOURCE AutoGenomics Inc

Copyright©2007 PR Newswire.

Page: 1 2

Related medicine technology :

1. Antidepressant Use May Boost Fracture Risk, From Harvard Womens Health Watch
2. Bipolar Disorder in Children Difficult to Diagnose, Reports the Harvard Mental Health Letter
3. Gene Chips to Detect CYP Variations: A New Step Toward Customized Medical Therapy.
4. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
5. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
6. TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment
7. Positive ZIO-201 Interim Phase II Sarcoma Data Presented at European Society for Medical Oncology
8. European Society for Medical Oncology (ESMO) Presents Data from the Clinical Trial of MediGenes Cancer-Killing Virus in Press Conference
9. The International Myeloma Foundation Says Data Reported at a Global Medical Meeting in Greece Demonstrates Improved Survival for a Wide Range of Myeloma Patients
10. Algeta Demonstrates Targeted Cancer-killing Potential of Novel Alpha Particle Linked Antibodies in Leading Medical Journal Blood
11. Vical Interim Clinical Results Demonstrate Safety and Tolerability of Inovio Biomedicals Electroporation DNA Delivery Technology

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/6/2009)...l/ -- NuVasive, Inc. (Nasdaq: NUVA ), a medical d...inimally disruptive surgical treatments for the sp... Lambert as Executive Vice President and Chief Fin...ompany also announced several other Executive Mana...ellent complement to the NuVasive family," said Al...
(Date:11/6/2009)...-- Philips Respironics applauds the efforts of the...to raise awareness about an important public healt...release of the first-ever government study to moni... a milestone in quantifying the size and scope of ...try leader and sleep therapy manufacturer, Philips...
(Date:11/6/2009).../ -- Keryx Biopharmaceuticals, Inc. (Nasdaq: KERX...r 10, 2009 at 8:30 a.m. EST to discuss the third q... for the remainder of 2009. Ron Bentsur, Chief Ex.... Keryx will announce its financial results for t...o the call. ,, In order to participate in the c...
Breaking Medicine Technology:NuVasive Appoints New Chief Financial Officer and Announces Additional Management Updates 2NuVasive Appoints New Chief Financial Officer and Announces Additional Management Updates 3NuVasive Appoints New Chief Financial Officer and Announces Additional Management Updates 4NuVasive Appoints New Chief Financial Officer and Announces Additional Management Updates 5Statement by Don Spence, CEO, Philips Home Healthcare Solutions, Endorsing CDC Educational Initiatives to Raise Awareness of Sleep Deprivation 2Keryx Biopharmaceuticals, Inc. to Hold Conference Call on Third Quarter 2009 Financial Results on Tuesday, November 10, 2009 at 8:30 a.m. EST 2Nick Jonas of the Jonas Brothers to Address the National Press Club on August 24 53272 1Nick Jonas of the Jonas Brothers to Address the National Press Club on August 24 53272 2Tevas Forum Draws Key Pennsylvania Healthcare Leaders 53270 1Tevas Forum Draws Key Pennsylvania Healthcare Leaders 53270 2Judge Sues Blue Cross for Autism Treatment 53268 1Judge Sues Blue Cross for Autism Treatment 53268 2
(Date:11/8/2009)...ILADELPHIA, Nov. 8 The ... the prevention and wellness provisions in the hea..., "With passage of this bill, the House takes im...g important insurance reforms and moving our healt...k to one that focuses on keeping people healthy," ...
(Date:11/8/2009)... pain now can take you out of the game later, doct...ws) -- Foot injuries are the talk of the NFL this ...anning and running back Willie Parker. , Offici...and American Academy of Podiatric Sports Medicine ...en they play fall sports like football and lacross...
(Date:11/8/2009)... New book called "Preventing... by Dr. Roberto Giraldo shows that AIDS is a resul...variety of so-called immune system stressor agents...nal and most of all, emotional. , ...From Nov. 6 – 8, 2009, cell biologists, phys...
(Date:11/8/2009)... A jury of 8 people in the Wester...woman $2,300,000 in pain and suffering for a medic...mes Tallman and Alicia Nocera of Thomas E. Crenney... the plaintiff, Vita Monestersky and against the U...ency total abdominal hysterectomy at age 18. , ...
(Date:11/8/2009)...SHINGTON, Nov. 7 USActi...ealth Care for America Act, which will make health...e companies accountable and increase access to hea...c option. ,, "Teddy Roosevelt, FDR and Harry Tr...or Alan Charney. "Today,s vote ranks among our cou...
Breaking Medicine News(10 mins):Health News:APHA Applauds Prevention and Wellness Provisions in House Health Reform Bill 2Health News:Rx for Fall Foot Injuries 2Health News:Revolutionary New Views on AIDS Highlight the Rethinking AIDS 2009 Congress; Emotional Issues can be a Significant Contributing Factor 2Health News:Revolutionary New Views on AIDS Highlight the Rethinking AIDS 2009 Congress; Emotional Issues can be a Significant Contributing Factor 3Health News:Pennsylvania Jury Awards $2.3 Million to Fayette County Woman in Medical Malpractice Case 2
Shiv Sena on Sunday strongly reacted to the recent Union Health Ministry notice to yoga guru Baba Ramdev,// saying the government is compromising national interests in connivance with multinational c
...cas County health department has reported that a S...ering meningitis// and was admitted to a hospital ...nabled the dates during which the Santa was workin...has advised all children who may have interacted w...
...deh, 30, Muir Beach, CA, was living day-to-day, ex...shortened life dependent// on kidney dialysis. She...donor” antibody levels were so high, her doctors b...inai Medical Center, Soraya successfully underwent...
... Lacks to Meet Inmates' Basic Health Needs – a Rep...s of at least 14 inmates since 1999 in the nation'...errors and other breakdowns in their medical care.... investigation by the Los Angeles Times found that...
...nish physician is to examine ailing Cuban leader F...alunya reported on Sunday.// Jose Luis Garcia...of the country's government. The doctor from Madri...is to give Castro a thorough examination and advis...
...e Institute Pasteur has recently shown that the tu...n its host's fat cells. //This formidable pathogen...iotics in these cells, in which it may remain dorm...e bacillus entirely from infected individuals shou...
Other Medicine News:Health News:Anti-rejection Therapy a Boon for Patients With "anti-donor" Antibody Levels 2Health News:Anti-rejection Therapy a Boon for Patients With "anti-donor" Antibody Levels 3Health News:Anti-rejection Therapy a Boon for Patients With "anti-donor" Antibody Levels 4Health News:Health Care Suffers at Los Angeles Jails: Report 2Health News:Tuberculosis: The Bacillus Takes Refuge in Adipose Cells 2
20MPX Digital Microscope Camera
QuantiFIRE 4-Megapixel Thermoelectrically-Cooled Digital Microscope Camera
MicroFire Digital Microscope Camera
...t technologically advanced Micro-dermabrasion mach...sive research, it offers the therapist safety, and... flexibility in skin exfoliation. It is superior t...sues are biologically respected. Through regular s...
Medicine Products: