Navigation Links
Hanmi and Kinex Announced Korean FDA Allowance of the KX01 IND Application
Date:11/6/2012

BUFFALO, N.Y. and SEOUL, South Korea, Nov. 6, 2012 /PRNewswire/ -- Kinex Pharmaceuticals and Hanmi Pharmaceutical announced today that the Korean FDA (KFDA) has accepted Hanmi's Investigational New Drug (IND) application for KX-01, Kinex's dual src/pretubulin inhibitor, in the oncologic setting. The data package included Kinex's preclinical and clinical data for KX-01, as well as Hanmi's preclinical gastric cancer data.

KX01 differentiates itself as an inhibitor that targets the kinase substrate pocket and therefore offers an excellent efficacy as well as safety profile. In addition, KX01 has potent inhibitory activity against pre-tubulin. KX01 has been shown to be very effective against a broad range of cancers in both in vitro experiments and in animal cancer models. Importantly, the compound has synergistic/additive activities with a number of first line chemotherapeutic agents. A completed Phase I study, in patients with end-stage cancer, showed a desirable safety profile and stable disease or clinical response in approximately 25% of the patients. Proof-of-concept studies are ongoing. The composition of matter of KX01 is covered by issued patents.

Dr. Gwan-Sun Lee, President and CEO of Hanmi said, "This is another important milestone in our successful partnership with Kinex. This also demonstrates our growing focus and commitment to oncology therapeutics."

"This is a major step forward," added Dr. Jeewoong Son, Senior VP and Head of Innovation R&D, at Hanmi. "The close collaboration between our scientific teams has helped define our initial development strategy. Kinex is a great partner and continues to show strong support. We will continue focus our efforts on unmet oncology needs together."

"Kinex is pleased to be working with such a committed partner," commented Dr. Lyn Dyster, SVP of Operations. "Hanmi's ability to work with their local regulatory bodies to advance the KX01 development program in Korea is a cr
'/>"/>

SOURCE Kinex Pharmaceuticals
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Xiangxue Pharmaceuticals to Acquire Rights for a Promising Drug Candidate from Kinex Pharmaceuticals for the Greater China Territory
2. Kinex Pharmaceuticals Receives Substantial Strategic Investment
3. Kinex Pharmaceuticals Appoints Mr. Patrick Gallagher Vice President of Business Development and Investor Relations
4. Gen-Probe Withdraws from Previously Announced Investor Presentations
5. Genesis Biopharma Announces Termination of Previously Announced Proposed Public Offering
6. LTCLINK-Tank Competition Announced To Introduce Your Emerging Product to the Aging Care Continuum
7. Delcath Announced Changes To Board Of Directors
8. Speakers Announced for the 2012 International Iridoid Research Symposium
9. Bausch + Lomb Announces Extension of Early Tender Date for Its Previously Announced Tender Offer for Its 9 7/8% Senior Notes due 2015 (CUSIP Nos. 071707AN3, U07190AA6 and 071707AP8)
10. Online Pharmacy Domain Policy Changes Announced by ICANN Registrar Internet.bs Corp.
11. Bausch + Lomb Announces Final Results for Its Previously Announced Tender Offer for Its 9 7/8% Senior Notes due 2015 (CUSIP Nos. 071707AN3, U07190AA6 and 071707AP8)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... Texas , Jan. 15, 2014  Novation, the leading ... awarded several new IT value-added reseller (VAR) national contracts ... IT goods and services at lower costs. These include ... services such as initiative assistance and ongoing IT consulting ...
(Date:1/15/2014)... 15, 2014 Massachusetts General Hospital (MGH), the ... ) announced today that they have launched a ... therapeutic targets and develop novel therapies for inflammatory ... millions worldwide. The MGH-Broad-Amgen collaboration brings together scientists ...
(Date:1/15/2014)... WORTH, Texas , Jan. 15, 2014  Humberto C. ... Dermatology Achievement Award" from the Journal of Drugs ... Aesthetic & Clinical Conference (ODAC). The event is January 17-20, ... Florida . The ODAC ...
Breaking Medicine Technology:New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 4
... compares favorably with endoscopic resection for advanced disease, and ... SUNNYVALE, Calif., June 3 Results from ... Digestive Disease Week (DDW) in Chicago this week, revealing ... the HALO ablation system for eradicating a pre-cancerous esophageal ...
... And All Subsequent Study Visits - , , ... Ltd., (DSP) announced today that positive results from a phase ... with schizophrenia have been published in The Journal of ... involving 180 patients with acute schizophrenia, evaluated a single fixed ...
Cached Medicine Technology:Definitive Outcomes of Radiofrequency Ablation for Barrett's Esophagus Using the HALO Ablation System Reported at the Digestive Disease Week Meeting for Gastroenterologists and Esophageal Surgeons 2Definitive Outcomes of Radiofrequency Ablation for Barrett's Esophagus Using the HALO Ablation System Reported at the Digestive Disease Week Meeting for Gastroenterologists and Esophageal Surgeons 3Definitive Outcomes of Radiofrequency Ablation for Barrett's Esophagus Using the HALO Ablation System Reported at the Digestive Disease Week Meeting for Gastroenterologists and Esophageal Surgeons 4Study Demonstrating Lurasidone Is Effective in Patients With Schizophrenia Published in The Journal of Clinical Psychiatry 2Study Demonstrating Lurasidone Is Effective in Patients With Schizophrenia Published in The Journal of Clinical Psychiatry 3Study Demonstrating Lurasidone Is Effective in Patients With Schizophrenia Published in The Journal of Clinical Psychiatry 4
(Date:7/11/2014)... 2014 The Europe Well Intervention Market report ... with analysis and revenue forecast. The well intervention services market ... in 2013 to $3.4 billion by 2018, at a CAGR ... TOC of the Europe Well Intervention Market report, to get ... a glimpse of the segmentation in the Europe well intervention ...
(Date:7/11/2014)... In people with sex addiction, pornography affects the brain ... drug addicts as they consume drugs, a new study ... between patients who have compulsive sexual behavior and healthy ... author Dr. Valerie Voon, of the University of Cambridge ... Voon,s research involved 19 men with sex addiction and ...
(Date:7/11/2014)... 11, 2014 The report “Probiotics ... Nutrients, Animal Feed), Applications (Regular, Therapeutic, Preventive Health ... Trends & Forecasts to 2019 ” defines and ... and forecasting of the market value of probiotic ... driving and restraining factors for the global market ...
(Date:7/11/2014)... Biostimulants are widely applied in turf and ... These also help turf and ornamentals in absorption of ... ornamentals, and flowers appear healthy and strong as a ... from the last few years. The most dominating region ... with around 40% share in 2013, and is estimated ...
(Date:7/11/2014)... 2014) Obese and overweight firefighters are not ... providers, according to new research from The University ... , National guidelines state that health care professionals ... maintaining a healthy weight. Firefighters have high rates ... cause of line-of-duty deaths in firefighters. This study ...
Breaking Medicine News(10 mins):Health News:Europe Well Intervention Services Market is Expected to Reach $3.4 Billion by 2018 - New Report by MicroMarket Monitor 2Health News:Europe Well Intervention Services Market is Expected to Reach $3.4 Billion by 2018 - New Report by MicroMarket Monitor 3Health News:Brains of Sex Addicts May Be Wired Like Those of Drug Addicts, Study Finds 2Health News:Probiotic Ingredient Market worth $1,732.8 Million by 2019 - A Report by MarketsandMarkets 2Health News:Probiotic Ingredient Market worth $1,732.8 Million by 2019 - A Report by MarketsandMarkets 3Health News:Probiotic Ingredient Market worth $1,732.8 Million by 2019 - A Report by MarketsandMarkets 4Health News:Probiotic Ingredient Market worth $1,732.8 Million by 2019 - A Report by MarketsandMarkets 5Health News:Biostimulants Market in Turf and Ornamentals is Expected to Reach $ 3.8 Billion by 2018 - New Report by MicroMarket Monitor 2Health News:Biostimulants Market in Turf and Ornamentals is Expected to Reach $ 3.8 Billion by 2018 - New Report by MicroMarket Monitor 3
... A problem in the lining of blood vessels may play ... a new study. The condition, called endothelial dysfunction, involves ... of cells that line blood vessels. Nitric oxide is crucial ... flow and the delivery of oxygen and nutrients to tissues. ...
... York, New YorkPremiums for employer-sponsored family health insurance increased ... to 2009, more than three times faster than median ... insurance is buying less. The report found that deductibles ... plus higher out-of-pocket costs are putting working families, budgets ...
... , WEDNESDAY, Dec. 1 (HealthDay News) -- Being exposed ... linked to dementia, a new study of agricultural workers suggests. ... who were in their 40s and 50s and had worked ... intellectual abilities were assessed twice, using nine tests designed to ...
... are nearly three times as likely as civilians to ... at Portland State University (PSU) and Oregon Health & ... Among Women With U.S. Military Service: A Hidden Epidemic?" ... Services , a journal published by the American Psychiatric ...
... By Kathleen Doheny HealthDay Reporter , WEDNESDAY, ... proven superior to other regimens for breast cancer that ... better for some women whose cancers haven,t spread, a ... these "node-negative" cancers, the drug combination of docetaxel, doxorubicin ...
... variations in a gene as important contributors to neuroblastoma, ... study team, led by researchers at The Children,s Hospital ... gene increase the risk of developing an aggressive form ... to drive the cancer,s progression once it forms. ...
Cached Medicine News:Health News:New Piece of Alzheimer's Puzzle Identified 2Health News:New report: Employer health insurance premiums increased 41 percent from 2003 to 2009 2Health News:New report: Employer health insurance premiums increased 41 percent from 2003 to 2009 3Health News:New report: Employer health insurance premiums increased 41 percent from 2003 to 2009 4Health News:Working With Pesticides May Affect Memory and More 2Health News:Suicide rate among young women veterans more than twice that of civilians 2Health News:Docetaxel May Boost Outcomes For Breast Cancers That Haven't Spread to Lymph 2Health News:Docetaxel May Boost Outcomes For Breast Cancers That Haven't Spread to Lymph 3Health News:New gene for childhood cancer neuroblastoma is discovered 2Health News:New gene for childhood cancer neuroblastoma is discovered 3
Designated most popular model or size. 4 mm wide tip....
Double-ended. Blunt and semi sharp 5 mm tips. Designated most popular model or size....
Double-ended. Semi sharp. Curved 3 mm tips. Angled right and left....
Double-ended. 6 mm x 9 mm and 6 mm x 11 mm tips....
Medicine Products: