Navigation Links
Halozyme Therapeutics Completes Enrollment in Chemophase Phase I/IIa Clinical Trial for Superficial Bladder Cancer
Date:9/25/2007

SAN DIEGO, Sept. 25 /PRNewswire-FirstCall/ -- Halozyme Therapeutics, Inc. (Nasdaq: HALO), a biopharmaceutical company developing and commercializing products based on the extracellular matrix, today announced that enrollment is complete in its Chemophase(R) Phase I/IIa clinical trial for the treatment of superficial bladder cancer. The Company began dosing patients in this trial in April of last year, following the successful completion of the initial Phase I trial of a single-administration of Chemophase and mitomycin. Patient enrollment in this Phase I/IIa trial required stepwise enrollment by escalating dose cohort, with a pause for safety evaluation required after the last patient in the previous cohort had completed at least the first four of the six weekly study drug instillations. Chemophase is a novel recombinant investigational therapeutic being developed to enhance the delivery of chemotherapy.

The Chemophase Phase I/IIa clinical trial is a multi-center, open label, nonrandomized study to evaluate multiple intravesical (into the bladder) administrations of Chemophase along with the widely used anticancer drug mitomycin in patients with superficial bladder cancer. This dose-finding Phase I/IIa study enrolled 27 patients with superficial bladder cancer. The objectives of the study included determining the maximum tolerated dose (MTD) and dose-limiting toxicities, if any, of escalating doses of mitomycin and then Chemophase in combination with mitomycin administered as weekly intravesical instillations for six weeks, consistent with the usual standard of care; establishing the optimal dose of Chemophase with mitomycin to be recommended for future studies; and observing patients for any preliminary evidenc
'/>"/>

SOURCE Halozyme Therapeutics, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
2. Cell Therapeutics, Inc. Management to Discuss Todays Announcement of Interim Pixantrone Study Results
3. CV Therapeutics Identifies Potential Anti-Diabetic Mechanism of Action for Ranexa
4. GTC Biotherapeutics to Webcast Corporate Presentation at the C.E. Unterberg, Towbin Emerging Growth Life Opportunities Conference
5. Fat Kills Cancer: Turning Stem Cells from Fat Tissue into Personalized, Cancer-Targeted Therapeutics
6. A 4-Week Therapy with Transition Therapeutics E1-I.N.T. Leads to Sustained Reductions in Blood Glucose Levels for 6 Months Post-treatment in Type 2 Diabetes Patients
7. Clinical Trial Suggests Bone Marrow Stem Cells Are Useful for Spinal Cord Injury; PrimeCell Therapeutics Provided Pre-Clinical Study
8. Pieris Progresses Development of its Proprietary Biotherapeutics Platform: Successful Demonstration of Dual Targeting With Duocalin(R) Technology
9. Opexa Therapeutics Reports Positive Top-line Data in Phase I/II Extension Trial with Tovaxin for Multiple Sclerosis
10. Orexigen Therapeutics to Present Data on Contrave Impact on Visceral Fat and Insulin Resistance at American Diabetes Association 67th Scientific Sessions in Chicago June 23
11. Allos Therapeutics Reports Results for Phase 3 Enrich Study of Efaproxyn in Women With Brain Metastases Originating From Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... , Aug. 27, 2014 ... report: Collaborative R&D Terms & ... https://www.reportbuyer.com/product/2276220/Collaborative-RD-Terms--Agreements-in-Pharma-Biotech-and-Diagnostics.html The Collaborative ... and Diagnostics report provides comprehensive understanding and ... and agreements entered into by the worlds ...
(Date:8/27/2014)... , Aug. 27, 2014 ... report: Co-development Terms & Agreements ... https://www.reportbuyer.com/product/2276221/Co-development-Terms--Agreements-in-Pharma-Biotech-and-Diagnostics.html The Co-development ... Diagnostics report provides comprehensive understanding and unprecedented ... entered into by the worlds leading life ...
(Date:8/27/2014)... PHOENIX , Aug. 27, 2014 /PRNewswire-iReach/ -- ... how to bridge the gap between the electronic ... contextually embedded links, readers can experience, first-hand, how ... patient record. Photo - http://photos.prnewswire.com/prnh/20140827/140443 ... providing central access to imaging from within the ...
Breaking Medicine Technology:Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics 2Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics 3Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics 4Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics 5Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics 6Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics 7Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics 8Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics 9Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 2Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 3Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 4Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 5Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 6Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 7DICOM Grid Launches Interactive Guide to Demonstrate Image-Enabling the EMR 2
(Date:8/27/2014)... All Canada Goose Parkas from CanadaGooseJackor.nu are great. ... modern. With unique detailing such as buttons, leather trim and ... up in opulence. Recently, the company has unveiled its new ... , True enough, the new assortment comes in various ... 28% off) on all these brand new items. By launching ...
(Date:8/27/2014)... 28, 2014 Top 10 Best SEO Hosting, ... Linux hosting suppliers and announced iPage, Bluehost and GoDaddy are ... Canada, Australia and Europe to buy useful hosting (including VPS ... reliable suppliers, iPage has been serving hosting small ... it has grown into a leader in the hosting industry ...
(Date:8/27/2014)... New Jersey’s own Morgan Hoffmann turned in a ... The Barclays – and thanks to finishing high on ... rounds, stepped his way into raising another $7,500 for ... New Jersey (Horizon BCBNSNJ) Walking Challenge. , Last Tuesday, ... family and friends at the Paramus course, to wear ...
(Date:8/27/2014)... uses topical agents and light to kill tissue) appears ... lesion caused by sun damage) at three months after ... lesions). , Author: Gayatri Patel, M.D., M.P.H., ... Sacramento, and colleagues. , Background: AKs are ... individuals with fair complexions who have had lots of ...
(Date:8/27/2014)... 2014 Sound Telecom, a leading telecommunications ... cloud-based business communication systems, has unveiled an article titled ... Secure Text Messaging .” The piece examines the world ... do to remain compliant with HIPAA and HITECH requirements. ... and C.O.O. at Sound Telecom, opens with evidence that ...
Breaking Medicine News(10 mins):Health News:CanadaGooseJackor.nu: 2014 Canada Goose Banff Parkas At Discounted Prices 2Health News:Well-known SEO Hosts Review Site Top10BestSEOHosting.com Recommends iPage, Bluehost and GoDaddy To Webmasters 2Health News:Morgan Hoffmann, PGA TOUR Pro & Wyckoff Native, golfs and walks his way to top 10 finish at The Barclays while raising additional $7,500 for charity 2Health News:Photodynamic therapy vs. cryotherapy for actinic keratoses 2Health News:Sound Telecom Releases Article on Secure Messaging with Huge Implications for the Healthcare Industry 2Health News:Sound Telecom Releases Article on Secure Messaging with Huge Implications for the Healthcare Industry 3
... on evaluating eHealth in the open access journal ... The University of Edinburgh, Edinburgh, Scotland outline the background ... the widespread investments in and adoption of information communication ... supported by a grant from the NHS Connecting for ...
... preliminary evaluation of methylation of two gene promoters in ... detect colorectal and gastric cancers, according to a new ... of the National Cancer Institute . Because ... the detection of gastrointestinal cancers, the development of nonintrusive ...
... levels of vitamin D are known to nearly double the ... at Washington University School of Medicine in St. Louis now ... deficient in vitamin D can,t process cholesterol normally, so it ... heart attack and stroke. The new research has identified a ...
... Pa., Aug. 21 InfoLogix, Inc. ("InfoLogix" or the "Company") ... enterprise mobility solutions for the healthcare and commercial industries, today ... the U.S. Securities and Exchange Commission ("SEC") in connection with ... proposed recapitalization plan of the Company and certain related matters. ...
... LITTLE FALLS, N.J., Aug. 21 CANTEL MEDICAL CORP. ... it received a letter of resignation from Ms. Elizabeth McCaughey as a ... director since 2005, stated that she was resigning to avoid any appearance ... , , About Cantel Medical Corp. ...
... jolt tied to chronic head pain, study finds , FRIDAY, ... headaches, may cause them if consumed in large quantities. , ... people who were questioned about caffeine intake and headache ... 2) in Norway. , The study was published recently in ...
Cached Medicine News:Health News:eHealth interventions need to be continuously evaluated 2Health News:Fecal DNA methylation detects gastric and colorectal cancers 2Health News:Research shows why low vitamin D raises heart disease risks in diabetics 2Health News:InfoLogix Files Preliminary Proxy Statement in Connection with Special Meeting of Its Stockholders to Approve Recapitalization Plan 2Health News:InfoLogix Files Preliminary Proxy Statement in Connection with Special Meeting of Its Stockholders to Approve Recapitalization Plan 3Health News:InfoLogix Files Preliminary Proxy Statement in Connection with Special Meeting of Its Stockholders to Approve Recapitalization Plan 4Health News:High-Octane Caffeine May Trigger Headaches 2
... Designs ROM post-operative knee braces are designed ... rehabilitation. , ,Adjustable and versatile, ROM ... for health care professionals. The braces are ... feature quick dial combination hinges that allow ...
... Neuroprene™ soft supports are a convenient, ... proprioceptive taping for common orthopedic conditions/instabilities. ... provide specific compression and lateral to ... (proprioceptors) in the skin and soft ...
... The Deluxe Heavy Duty Drop Lock Post Operative ... pin hinge with a spring loaded drop lock ... arms and contoured plates prevent the brace from ... a tibial offset for anatomical alignment that controls ...
... might just be the world's most versatile ... support, post-op/rehab support, or both, Flex is ... Accutrac™ ROM hinges control flexion and extension ... durability while being heat-moldable to accommodate changes ...
Medicine Products: