Navigation Links
Halo Therapeutics Reports Favorable Independent Review of Lead Drug Candidate HT-100
Date:3/20/2012

NEWTON, Mass., March 20, 2012 /PRNewswire/ -- Halo Therapeutics, LLC, a clinical-stage biopharmaceutical company developing novel therapeutics for rare fibrotic diseases, announced today that the TREAT-NMD Advisory Committee on Therapeutics (TACT) has reviewed HT-100, Halo's drug candidate for Duchenne muscular dystrophy (DMD), and believes the compound has potential based on the proposed mechanism. TREAT-NMD is a global network dedicated to expediting the delivery of promising new therapies to patients with neuromuscular disease. TACT provides independent, objective guidance on the therapeutic potential of drug candidates (novel or repurposed), which are submitted for review on a voluntary basis. In its review of HT-100, TACT found the drug candidate to be "ready for the clinic."

"TACT offers the opportunity for objective review of potential new therapies to help industry, researchers and patient advocacy groups. The review provides multi-disciplinary advice on the development of the potential therapies in the context of a realistic development pathway," said Volker Straub of TREAT-NMD. "TACT evaluated the proposal from Halo Therapeutics and felt it was well prepared, and that the compound has potential based on the proposed mechanism. Overall the plan to progress to a clinical trial is realistic."

DMD is a progressive and fatal neuromuscular disorder that afflicts approximately 1 in 3,500 boys worldwide.  HT-100, Halo's proprietary formulation of halofuginone, is an orally available small molecule drug candidate intended to reduce fibrosis and promote healthy muscle fiber regeneration. HT-100 works by inhibiting the pathological fibrotic process in muscle and directly stimulating healthy muscle fiber regeneration. The U.S. Food and Drug Administration recently granted orphan drug designation to HT-100. The company will begin a phase 2 study in the second half of 2012.

"We submitted HT-100 for a TACT review knowing that informed, objec
'/>"/>

SOURCE Halo Therapeutics, LLC
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Echo Therapeutics, Inc. Announces 2011 Financial Results
2. Stemline Therapeutics Appoints Kevin Buchi, Former CEO of Cephalon, to Its Board of Directors
3. Nile Therapeutics Announces Upcoming Data Presentation at the American College of Cardiology Annual Scientific Meeting
4. Prime Therapeutics Announces CareCentered Contract™ with EMD Serono, Inc. for MS Drug Rebif®
5. ADHD Therapeutics Reviewed by NeuroPerspective
6. Cell Therapeutics, Inc. (CTI) Reports Fourth Quarter and Year-End Financial Results and Milestones
7. Cell Therapeutics, Inc. (CTI) to Report Fourth Quarter and Year-End 2011 Financial Results on March 7
8. Particle Sciences Acquires Exclusive License to Lyotropic Therapeutics Drug Delivery Technology
9. Nektar Therapeutics Reports Fourth Quarter and Year-End 2011 Financial Results
10. Nektar Therapeutics Announces Agreement to Sell CIMZIA® and MIRCERA® Royalties to Royalty Pharma for $124 Million
11. Halozyme Therapeutics to Present at the CITI 2012 Global Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... , Sept. 17, 2014   MedeAnalytics ... solution that brings complete visibility to a provider,s ... an ever-evolving reimbursement landscape. Powered by the industry,s ... to the critical point between patient access and ... The solution will improve revenue capture, minimize audit ...
(Date:9/17/2014)... , Sept. 17, 2014  The law ... today announced that it will serve as host ... and Avoiding the Risks of Healthcare Reform," a ... will examine delivery systems, reimbursement, compliance and enforcement ... Act. Logo -  http://photos.prnewswire.com/prnh/20140916/146606 ...
(Date:9/17/2014)... , Sept. 17, 2014 Cardiac Dimensions ... data from the TITAN II clinical trial of ... and sustained improvements in mitral regurgitation, functional improvement, ... long-term safety and efficacy data, which was consistent ... Sept. 13 at the 26 th annual ...
Breaking Medicine Technology:MedeAnalytics Unveils New Revenue Integrity Solution to Support the Transition to Value-Based Healthcare 2MedeAnalytics Unveils New Revenue Integrity Solution to Support the Transition to Value-Based Healthcare 3Three Leading Healthcare Organizations Sponsor Conference to Examine Opportunities and Risks of Healthcare Reform for Providers 2Cardiac Dimensions Announces New Long-Term Outcomes Data From TITAN II Clinical Trial Demonstrates Safety, Efficacy Of Enhanced CARILLON Mitral Contour System 2Cardiac Dimensions Announces New Long-Term Outcomes Data From TITAN II Clinical Trial Demonstrates Safety, Efficacy Of Enhanced CARILLON Mitral Contour System 3
... BioSpecifics Technologies Corp. (Nasdaq: BSTC ), ... today announced that BioSpecifics, President, Tom Wegman, will present ... Conference on Friday, October 22, 2010 at 3:00 pm ... New York. A live webcast of ...
... Network, already the largest distributor of FDA-approved drug ... that this month it will surpass six million ... ("REMS") program alerts delivered to prescribers. FDA-approved Drug-Alerts ... Network,s Health Care Notification Network (HCNN) service since ...
Cached Medicine Technology:PDR Network Delivers Six Million Drug Alerts & REMS 2PDR Network Delivers Six Million Drug Alerts & REMS 3
(Date:9/17/2014)... Phoenix, Arizona (PRWEB) September 17, 2014 ... valuable option for children who cannot live with their ... is necessary to continue to enhance services and supports ... League of America’s (CWLA) National Kinship Care Conference is ... field’s collective knowledge of best practice, policy, program and ...
(Date:9/17/2014)... City, UT (PRWEB) September 17, 2014 ... America 2015 Kira Kazantsev and ushered in a ... charitable support. As Miss America Organization’s official national ... welcoming Kazantsev as its newest National Goodwill Ambassador. ... at member Children’s Miracle Network Hospitals across the ...
(Date:9/17/2014)... spaceflight has been reserved for the very healthy. ... the highest physical and psychological standards to prepare ... advent of commercial spaceflight, average people can now ... had very little information about what medical conditions ... the spaceflight environment, as most medical conditions have ...
(Date:9/17/2014)... research study was announced today that will analyze ... long-term wellness and contribute to healthy aging. ... and funded through a $10 million unrestricted gift ... WELL aims to identify lifestyle and environmental factors ... wellness as they age. WELL will be designed, ...
(Date:9/17/2014)... struggle to distinguish between a business strategy and business plan, ... answer by reading Per Wickstrom’s latest blog post. , “The ... and a business strategy are both strategic – and what’s ... view it is that a business plan is part one, ... , According to the blog post, a business plan is ...
Breaking Medicine News(10 mins):Health News:Arizona’s Children Association Kinship Service Providers Invited to Present at the CWLA National Conference 2Health News:Miss America 2015 Kira Kazantsev Takes On Role as Children’s Miracle Network Hospitals National Goodwill Ambassador 2Health News:Miss America 2015 Kira Kazantsev Takes On Role as Children’s Miracle Network Hospitals National Goodwill Ambassador 3Health News:Space: The final frontier… open to the public 2Health News:First-ever research study examines impacts of diet and lifestyle on healthy aging 2Health News:Per Wickstrom’s Latest Blog Explores the Difference Between a Business Plan and a Business Strategy 2
... Huntington,s disease may give patients hope for a cure. ... tissue of Huntington,s disease patients determined that an overactive ... cells to die. Toning down the activity of that ... kept those cells alive, according to the research team ...
... medical literature on cannabis use and sexual health has ... performance. "Cannabis is the most widely-used illicit drug ... Department of Pharmacology and Toxicology. "It is also often ... of the hazardous effects it may be having on ...
... the brain may need a new name, say scientists who ... finding, published in PLoS One , may help explain ... of surviving it, according to scientists at Georgia Health Sciences ... off a building or just the thought of either ...
... Jerusalem, February 22, 2011 -- The portion of the brain ... to a new study by researchers from the Hebrew University ... blind people as they read words in Braille show activity ... up when sighted readers read. The findings challenge the textbook ...
... consecutive year, Women & Infants Hospital of Rhode Island ... Care by the Clinical Sciences Institute of OptumHealth, an ... health care providers are created equal. For complex ... a rigorous evaluation process, OptumHealth developed Centers of Excellence ...
... herald the onset of major depression and the associated ... Research that focuses on access to treatment for adolescents ... persistent disparities based on race and ethnicity. Unfortunately such ... across all individuals and communities has yet to be ...
Cached Medicine News:Health News:Huntington's disease breakthrough equals hope for patients 2Health News:Brain's 'reward' center also responds to bad experiences 2Health News:Brain doesn't need vision at all in order to 'read' material 2Health News:Brain doesn't need vision at all in order to 'read' material 3Health News:Women & Infants named Center of Excellence for Neonatal Care for fifth year 2Health News:Racial and ethnic minority adolescents less likely to receive treatment for major depression 2
5 mm tying platform. Round knurled handle with dull finish. Curved shafts. Overall length 3.9 inches....
Straight shafts and tips with 5.5 mm tying platform. 0.3 mm gap at platform heel. True round knurled handle in closed position with polished finish. Overall length 4.3 inches....
Curved shafts with 12 mm tying platform. Serrated handle with polished finish. Overall length 4.3 inches....
Hartman Mosquito forceps, straight, 3-1/2", German stainless steel...
Medicine Products: