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Halo Therapeutics Raises $1.1 Million to Expedite Phase 2 Study of HT-100
Date:5/22/2012

NEWTON, Mass., May 22, 2012 /PRNewswire/ -- Halo Therapeutics, LLC, a clinical-stage biopharmaceutical company developing novel therapeutics for rare fibrotic diseases, announced today that it has received financial support totaling $1.1 million from 12 not-for-profit foundations serving the muscular dystrophy patient community. Halo will use the funds to expedite the phase 2 study of HT-100, its lead drug candidate for Duchenne muscular dystrophy (DMD). HT-100, a proprietary formulation of halofuginone, is an orally available small molecule drug candidate being developed to reduce fibrosis and promote healthy muscle fiber regeneration in DMD patients. Halo will begin its phase 2 study in the second half of 2012.

"Companies typically labor for years to attract the level of engagement we have received from such an active, dedicated patient advocacy community," said Marc Blaustein, CEO of Halo Therapeutics. "We are both humbled and heartened by their support and believe that together we are better able to speed the delivery of new therapies for DMD to patients and their families."

DMD is a progressive and fatal neuromuscular disorder, which afflicts approximately 1 in 3,500 boys worldwide. There is currently no treatment. Muscle fibrosis is a primary outcome and ultimately leads to early patient death: Young men with DMD typically live into their twenties or early thirties. In studies, HT-100 has demonstrated potent ability to halt and reverse existing muscle fibrosis as well as promote the growth of healthy new muscle. In an independent review, an international advisory committee of neuromuscular disease experts concluded HT-100 was "ready for the clinic." The drug candidate has received Orphan status in both the U.S. and the EU.

"The community of muscular dystrophy foundations has rallied around our novel and aggressive approach to delivering a promising therapy to DMD boys and their families," said Tom Wicka, founder of the Nash A
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SOURCE Halo Therapeutics, LLC
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