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HIV/AIDS Research Network Recommends Use of Abbott RealTime Viral Load Test for NIH-Sponsored Clinical Trials
Date:5/7/2009

onsored clinical trials networks in the global effort to evaluate and monitor HIV drug treatments."

Based on several published studies, current molecular or PCR based diagnostic tests vary in their ability to detect and reliably quantify variant strains of HIV-1 and have been found to under-quantify them. "The performance and precision of the Abbott RealTime HIV-1 assay for detecting variant subtypes allows physicians to confidently measure viral levels and provide optimal drug treatment," O'Kelly said.

The NIH-sponsored networks include the: AIDS Clinical Trials Group, International Maternal Pediatric Adolescent AIDS Clinical Trials Group, HIV Prevention Trials Network, HIV Vaccine Trials Network, and Microbicide Trials Network. The networks are an affiliated group of national and international medical research institutions and investigators that conduct clinical HIV/AIDS research to develop safe and effective drugs, prevention strategies and HIV vaccines.

About the Abbott RealTime HIV-1 Test

The Abbott RealTime HIV-1 assay is among the most sensitive viral load tests available today. The test has demonstrated the ability to detect diverse group M subtypes of HIV (including all known non-B subtypes) as well as group N and O isolates.

The Abbott RealTime HIV-1 test is intended for use in conjunction with clinical presentation and other laboratory markers as an indicator of disease prognosis and for use as an aid in assessing viral response to antiretroviral treatment as measured by changes in plasma HIV-1 RNA levels. The assay is not intended to be used as a donor-screening test for HIV-1 or as a diagnostic test to confirm the presence of HIV-1 infection.

About the Abbott m2000 Instrument System

The Abbott RealTime HIV-1 test runs on the Abbott m2000, an automated system that us
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