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HEALTHPOINT-Sponsored Venous Leg Ulcer Clinical Trial Enrolls First Subject for Second Phase II Study
Date:6/16/2009

asts, the two major cell types found in human skin. Using a unique delivery system, the cells are sprayed onto the wound surface in a self-polymerizing protein mesh intended to help the cells to adhere to the tissue.

Previous research strongly suggests that wound healing is accelerated by the application of living cells, particularly when both keratinocytes and fibroblasts are present together. By allowing the cells to be in contact with each other following spraying onto the wound surface, it is thought that growth promoting and healing signals will be generated that can support healing of the wound by the patient's own cells.

Typically caused by impaired microcirculation secondary to venous hypertension, venous leg ulcers are increasingly common, are costly, and are often a cause of prolonged suffering for patients. Characterized as difficult to heal, many such ulcers develop into chronic, nonresponsive wounds despite application of standard treatments.

"Making an innovative, effective treatment available is a strategy that can help such high risk wounds and provide tremendous benefits to both patients and society," said Dr. Slade. "Based on an estimated 2.5 million venous leg ulcers in the United States alone and actual direct treatment costs reported to be over $9,000 per patient, the current annual cost of treating these wounds is likely in the many billions of dollars."

"We are excited to be working with HEALTHPOINT on this important study," said Dr. Reyzelman. "We're aided greatly by HEALTHPOINT's investment in cutting edge technology to support this trial, including new laser-equipped digital cameras that can measure wound size at each clinic visit."

"We believe development of our HP802-247 product will result in helping millions of patients worldwide who suffer from these ulcers," said Travis E. Baugh, President of HEALTHPOINT. "The novel format of this cell-based ther
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SOURCE HEALTHPOINT, Ltd.
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2. Healthpoint Initiates Phase II, Dose-Finding Study to Evaluate Effectiveness of a Unique Cell Based Therapy in Venous Leg Ulcers
3. MEDIHONEY(TM) Dressings Shown to Help Improve Outcomes of Non-Healing Venous Leg Ulcers in Recent Case Series
4. Pivotal Phase III Data Confirm the Efficacy and Safety of Arpidas Intravenous Iclaprim in Treating Patients With Complicated Skin and Skin Structure Infections
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7. Wound Management Technologies, Inc. Announces Agreement for Evidence Based Study for Diabetic Venous Ulcers
8. Randomized Controlled Clinical Trial Shows Derma Sciences MEDIHONEY(TM) Eradicates MRSA From Chronic Venous Ulcers
9. Phase I/II Study of Targeted Gene Delivery In Vivo - Intravenous Infusions of REXIN-G - Demonstrates Dose-Dependent Anti-Tumor Activity Without Toxicity in Patients With Progressive Chemo-Resistant Bone and Soft Tissue Sarcoma (ASCO 2008)
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