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Ground-breaking Research Identifies Molecular Subtyping as a Key to Determining Prognosis and Benefit of Chemotherapy for Breast and Colorectal Cancers
Date:5/31/2013

IRVINE, Calif., May 31, 2013 /PRNewswire/ -- Agendia, a world leader in molecular cancer diagnostics, today announced that results from five studies focused on breast, colon and colorectal cancer will be presented at the upcoming American Society of Clinical Oncology (ASCO) Annual Meeting to be held May 31-June 4, 2013 at McCormick Place in Chicago. Of particular importance are the studies which demonstrate that molecular subtyping allows for improvement in therapy selection and overall patient survival. 

The posters covering breast cancer include:

  • Effectiveness of MammaPrint® and BluePrint® in identifying molecular subtypes of breast tumors as a predictor for tumor response to targeted chemotherapies.
  • MammaPrint MINT study assesses the ability of molecular profiling and traditional pathologic and clinical prognostic factors to predict patient response to neo-adjuvant chemotherapy.
  • Genomic profiling of breast cancer in African American women.

"It is clear that molecular subtypes are key pieces of information in determining the best course of treatment for breast cancer patients, and that subtyping will only become more important as hundreds of targeted therapies reach the market in the coming decade," said Agendia CEO David Macdonald .

The posters/discussions covering colorectal and colon cancer include:

  • Intrinsic subtypes of colorectal cancer that direct different treatment strategies.
  • The use of ColoPrint® as a predictor of outcome and chemotherapy benefit in stage II and III colon cancer patients.

"Like breast cancer, where molecular classification into subtypes has clear relevance for prognosis and treatment, we are finding clinically relevant subtypes for colorectal and colon cancer," Macdonald added. "Agendia has a rich history of presenting innovative and ground-breaking research that benefits oncologists and their cancer patients."

A more complete list of presentation abstracts can be found on ASCO's website at www.asco.org.

About Agendia:
Agendia is a leading molecular diagnostic company that develops and markets FFPE-based genomic diagnostic products. Agendia's breast cancer Symphony suite was developed by analyzing the complete human genome, ensuring 100% definitive results for cancer patients. Together, these tests help physicians determine a patient's individual risk for metastasis, which patients will benefit from chemo, hormonal, or combination therapy, and which patients do not require these treatments and can instead be treated with other less arduous and less costly methods.

In addition to the Symphony suite of tests, Agendia has a rich pipeline of genomic products in development. The Company collaborates with pharmaceutical companies, leading cancer centers and academic groups to develop companion diagnostic tests in the area of oncology and is a critical partner in the ISPY-2 and MINDACT trials.  For more information, please visit www.agendia.com.


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