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Goodwin Biotechnology Announces a Collaboration With Alethia Biotherapeutics
Date:6/2/2011

PLANTATION, Fla. and MONTREAL, June 2, 2011 /PRNewswire/ -- Goodwin Biotechnology, Inc. (GBI), a full service CMO focused on process development and GMP manufacturing of cell culture derived biopharmaceuticals, and Alethia Biotherapeutics, Inc., a biotechnology company focused on monoclonal antibody development with a very sensitive and highly disease-tissue specific proprietary target discovery platform, announced a collaboration on the development of a mammalian cell line-based IgG monoclonal antibody project that is anticipated to make a significant impact in the treatment of selected cancers. Terms of the agreement were not disclosed.

"AB-16B5 is a humanized IgG2 monoclonal antibody which targets secreted clusterin for the inhibition of cancer-associated epithelial-to-mesenchymal transition (EMT), and it has shown positive pre-clinical results in representative cancer models derived from various solid tumors," notes Mario Filion, Ph.D., Executive VP and CSO at Alethia Biotherapeutics. "And, we are pleased to select GBI as our development and GMP manufacturing partner for our first product candidate."

"We at GBI would like to echo that comment. We are pleased to partner with Alethia Biotherapeutics on this important project," says SooYoung Lee, PhD and Senior Vice President of Operations at GBI. "In the biologics CMO niche, we were among the first to engineer the concept of 'full integration', which enables us to work with our clients from Proof of Concept through the manufacture of pre-clinical, and clinical trial products. It is a process we termed 'GMPnization'. In other words, we begin with the end in mind. We employ appropriate stringent regulatory and quality systems to supply product candidates during the development cycle from the initial 'production' cell line development all the way through scale up steps leading to the final cGMP compliant manufacturing process and vialing of the final biopharmaceutical product."

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SOURCE Goodwin Biotechnology, Inc.
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