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Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users
Date:1/15/2014

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CHAPTER 3 OVERVIEW 9

NEED FOR THE DOSAGE FORMS 9TABLE 1 HISTORIC EVENTS IN DRUG DELIVERY 10CLASSIFICATION OF DRUG DELIVERY ACCORDING TO TECHNOLOGY 11SUSTAINED RELEASE DRUG DELIVERY 11Oral Sustained Release Drug Delivery 11Intramuscular (IM) Injections or Microsyringes 12TABLE 2 ADVANTAGES AND DISADVANTAGES OF SUSTAINED RELEASE DRUGDELIVERY 12PRODRUGS 13Subtypes of Prodrugs 14TABLE 3 CLASSIFICATION OF PRODRUGS 14Need for Prodrugs 15TABLE 4 ADVANTAGES AND DISADVANTAGES OF PRODRUGS 15IMPLANTS AND INTRAUTERINE DEVICES (IUDS) 16Copper-based Devices 16Hormonal-based Devices 16Mechanism 17TABLE 5 ADVANTAGES AND DISADVANTAGES OF IMPLANTS AND IUDS 17TARGETED DRUG DELIVERY 18Delivery Vehicles 18Liposomes 18TABLE 6 ADVANTAGES AND DISADVANTAGES OF LIPOSOMES 19Micelles and Dendrimers 19Mechanisms of Drug Delivery 19Advantages of Dendrimers 20Biodegradable Particles 20Artificial DNA Nanostructures 20Monoclonal Antibodies 21Applications 21TABLE 7 ADVANTAGES AND DISADVANTAGES OF MONOCLONAL ANTIBODIES 22POLYMERIC DRUG DELIVERY 22Applications of Polymers in Drug Delivery 22TABLE 8 ADVANTAGES AND DISADVANTAGES OF POLYMERS 23Pegylation 23TABLE 9 ADVANTAGES AND DISADVANTAGES OF PEGYLATION 24Future Perspectives 24CLASSIFICATION OF DRUG DELIVERY BY ROUTE OF ADMINISTRATION 24ORAL DRUG DELIVERY 24TABLE 10 ADVANTAGES AND DISADVANTAGES OF ORAL DRUG DELIVERY 25INJECTABLE OR PARENTERAL DRUG DELIVERY 25TABLE 11 ADVANTAGES AND DISADVANTAGES OF PARENTRAL DRUG DELIVERY 25PULMONARY DRUG DELIVERY 26TABLE 12 ADVANTAGES AND DISADVANTAGES OF PULMONARY DRUG DELIVERY 26NASAL DRUG DELIVERY 27TABLE 13 ADVANTAGES AND DISADVANTAGES OF NASAL DRUG DELIVERY 27ORAL MUCOSAL DRUG DELIVERY 27TABLE 14 ADVANTAGES AND DISADVANTAGES OF ORAL MUCOSAL DRUGDELIVERY 28RECTAL DRUG DELIVERY 28TABLE 15 ADVANTAGES AND DISADVANTAGES OF RECTAL DRUG DELIVERY 28OCULAR DRUG DELIVERY 29TABLE 16 ADVANTAGES AND DISADVANTAGES OF OCULAR DRUG DELIVERY 29TRANSDERMAL DRUG DELIVERY 29TABLE 17 ADVANTAGES AND DISADVANTAGES
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