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Global Imaging Agents Industry

' Antibody Technology 48

First Generation 48

Second Generation 48

Third Generation 48

NeoRx's "Painting the Target" Technology 49

Stage - I 49

Stage - II 49

Stage - III 49

Gas Encapsulation Technology for Ultrasound Contrast Media 49

Pharmacyclics' Texaphyrin Technology 50

Regulatory Bodies 50

Ultrasound Contrast Agents Are Drugs, Not Devices - Rules US FDA 50

Entry Barriers 50

Research Driven Markets 50

Highly Competitive Market 51

Economies of Scale 51

Substitutes in Agents Manufacturing 51

New X-ray Diagnostic Agents 51

Amide-based Macrocyclic Ligands - Potential MRI Agents 51

Gadolinium (III) Complexes - Potential MRI Contrast Agents 51

Metal-Containing Compounds Act As Potential Contrast Agents 51

Therapeutic Applications 51

Diagnostic Applications 52

Magnetic Gels as Potential MRI Contrast Agents 52

PFCs as Diagnostic Contrast Agents 52


GE Healthcare Receives FDA Approval for DaTscan for detecting

Dopamine Transporters 53

Targeson Launches Targestar® P-HF 53

GE Healthcare Announces Phase II Study Results of

Flutemetamol, the PET Imaging Agent for Brain Imaging 53

GE Healthcare Receives FDA Approval for Cysview, An Optical

Imaging Agent for Cystoscopic Detection of Papillary Bladder

Cancer 53

INER Develops Imaging Agents for Cerebral Blood Flow 54

Lantheus Medical Imaging Introduces Definity Ultrasound

Contrast Imaging Agent in India 54

Sanochemia Pharmazeutika Completes DCP Phase of MRT Imaging

Agent, to Introduce Within Major European Markets by 2011 54

Bayer Transfers Liver MRI Contrast Medium Resovist Injection

to I'rom Pharmaceutical 54

GE Healthcare Re-Introduces Contrast Agent, OptisonTM 54

Lantheus Medical Imaging Introduces ABLAVAR͐

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