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Global Hormone Replacement Therapy (HRT) Industry
Date:11/7/2011

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Vaginal Estrogen Ring 28

Transdermal Estrogen Skin Patches 28

Localized Treatment 29

Vaginal Estrogen Tablets 29

Estrogen Creams 29

Intrauterine Progestin System (IUS) 29

Lower Dose Vaginal Estrogen Ring 29

Vaginal Progesterone Gel 29

Bioidentical Hormone Replacement Therapy (BHRT) 30

Divigel: A BHRT 30

Historical Background 31

More Claims than Evidence 31

Regulatory Scenario in the US 32

Other Alternatives 32

Prescription Medication 32

Gabapentin 33

Clonidine 33

SNRIs and SSRIs 33

Botanicals 33

Black Cohosh 33

Phytoestrogens (Isoflavones) 33

Other Botanical Products 33

Non-botanical Supplements 34

Mind/Body therapies 34

Exercise and Diet 34

5. RECENT INDUSTRY ACTIVITY 35

BioNovo to Conduct Phase III Clinical Trials for Menerba 35

Novo Nordisk Unveils Vagifem® 10µg 35

Pfizer Global Manufacturing to Reconfigure Global Plant Network 36

Amgen Obtains FDA Approval for Prolia in Treating

Postmenopausal Women at Greater Risk of Osteoporosis 36

Watson Enters into Agreement to Acquire US rights of CLI's

Bioadhesive Progesterone Gel 36

Solvay Divests Pharmaceutical Business 37

NaturalNectar Introduces EaseFemin Menopausal Support 37

Hisamitsu Pharmaceutical Acquires Noven Pharmaceuticals 37

Wyeth Receives FDA Approval for Premarin Vaginal Cream 0.5 gm 38

Wyeth Conducts Phase III SMART-1 Clinical Trial for

Bazedoxifene/Conjugated Estrogens 38

The Competition Bureau Enters Into Agreement with Pfizer and

Wyeth for Resolving Competition Concerns 38

BodyLogicMD Introduces Updated Website 39

Bayer Launches Angeliq® in Canada 39

ASKA Receives Approval for Menoaid Combipatch 39

Depomed Initiates Gabapentin GR Phase III Trials 39

Dutch Authority Acce
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