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Global Hormone Replacement Therapy (HRT) Industry
Date:11/7/2011

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Select Hormone Therapies for the Treatment of Postmenopausal

Symptoms by Manufacturer 15

Select Hormone Therapies for the Treatment of Postmenopausal

Symptoms by Manufacturer 16

Select Hormone Therapies for Post Menopausal Women by Year of

Patent Expiry 16

Select Hormone Therapies for Treatment of Postmenopausal

Symptoms by Generic Manufacturers 17

4. PRODUCT OVERVIEW 18

What are Hormones? 18

What is Menopause? 19

Menopause Symptoms and Complaints 19

What is Hormone Replacement Therapy? 19

Why HRT? 20

FDA-Approved Hormones 21

Estrogen 21

Progestins 21

Contraindications of HRT 21

Hormones Currently under the FDA's Consideration 21

Testosterone 21

Dehydroepiandrosterone (DHEA) 22

Historical Progression 22

Advantages and Disadvantages of Using HRT 22

Benefits of Hormone Therapy 23

Relief from Vasomotor Symptoms 23

Vaginal Symptoms 23

Improvement in Sexual Functioning 23

Urinary Health 23

Management of Variations in Body Weight/ Mass 23

Ensuring Quality of Life 24

Osteoporosis 24

Diabetes Mellitus (DM) 24

Impact on Overall Mortality 24

Risks Involved in Hormone Therapy 24

Hormone Therapies in HRT and their Effect 25

Potential Benefits and Risks of HRT in Menopausal Symptoms 26

Common and Less Common Side Effects of Using Estrogen-alone,

Progesterone-alone or Combination Therapies 26

Potential Issues 26

Cardiovascular Problems 26

Coronary Heart Disease (CHD) 26

Stroke 27

Venous Thromboembolism (VTE) 27

Endometrial Cancer 27

Breast Cancer 27

Estrogen-Progestogen Therapy 27

Estrogen Therapy 27

Lung Cancer 28

Depression and Mood Swings 28

Ovarian Cancer 28

Routes of Administration 28

Systemic Treatment 28

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