RICHMOND, Va., and SAN DIEGO, Sept. 25, 2013 /PRNewswire/ -- Global Genomics Group (G3) and Illumina, Inc. (NASDAQ: ILMN) today announced that they have entered into a partnership to investigate novel biomarkers and biological pathways involved in the development and diagnosis of cardiovascular diseases. Under the terms of the agreement, Illumina will conduct whole genome sequencing (WGS) in the GLOBAL (Genetic LOci and the Burden of Atherosclerotic Lesions) clinical study. GLOBAL is the largest pan-omic study combining genomics, epigenomics, transcriptomics, proteomics, metabolomics, lipidomics, lipoprotein proteomics and glycomics with coronary computed tomographic (CT) angiography, an advanced imaging technology for phenotyping that allows the precise classification of disease in patients.
"The development and progression of conditions such as cardiovascular disease involves poorly understood complex biological processes that require comprehensive investigative approaches to identify new disease biomarkers and therapeutic targets," said Szilard Voros, M.D., chief executive officer and co-founder of G3. "This is the first study of its kind, analyzing trillions of data points from 7,000 patients, designed to investigate the biological basis behind the complex processes responsible for atherosclerosis. We are applying the most advanced coronary CT angiography techniques to precisely phenotype atherosclerotic disease, while conducting a complete pan-omic analysis in every patient. WGS is a centerpiece of this landmark study, and this collaboration with Illumina and its most advanced next-generation sequencing technology is essential to the success of the program. To date we have collected more than 2,200 samples, and we anticipate comple
|SOURCE Global Genomics Group (G3); Illumina, Inc.|
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