Navigation Links
Global Genomics Group (G3) and Illumina to Partner on Cardiovascular Genomics
Date:9/25/2013

RICHMOND, Va., and SAN DIEGO, Sept. 25, 2013 /PRNewswire/ -- Global Genomics Group (G3) and Illumina, Inc. (NASDAQ: ILMN) today announced that they have entered into a partnership to investigate novel biomarkers and biological pathways involved in the development and diagnosis of cardiovascular diseases. Under the terms of the agreement, Illumina will conduct whole genome sequencing (WGS) in the GLOBAL (Genetic LOci and the Burden of Atherosclerotic Lesions) clinical study. GLOBAL is the largest pan-omic study combining genomics, epigenomics, transcriptomics, proteomics, metabolomics, lipidomics, lipoprotein proteomics and glycomics with coronary computed tomographic (CT) angiography, an advanced imaging technology for phenotyping that allows the precise classification of disease in patients.

"The development and progression of conditions such as cardiovascular disease involves poorly understood complex biological processes that require comprehensive investigative approaches to identify new disease biomarkers and therapeutic targets," said Szilard Voros, M.D., chief executive officer and co-founder of G3. "This is the first study of its kind, analyzing trillions of data points from 7,000 patients, designed to investigate the biological basis behind the complex processes responsible for atherosclerosis. We are applying the most advanced coronary CT angiography techniques to precisely phenotype atherosclerotic disease, while conducting a complete pan-omic analysis in every patient. WGS is a centerpiece of this landmark study, and this collaboration with Illumina and its most advanced next-generation sequencing technology is essential to the success of the program. To date we have collected more than 2,200 samples, and we anticipate completing enrollment by summer of 2014."

Matt Posard, senior vice president and general manager of Illumina's Translational and Consumer Genomics business, added, "Consistent with Illumina's strategy of partnering with clinical thought leaders, we are excited to expand our footprint in cardiovascular genomics with G3. The GLOBAL study will be one of the largest patient studies involving genomic sequencing and will be the largest pan-omic WGS study Illumina has participated in to date. The sequencing data will be a critical component in deciphering the complexities of the development and diagnosis of atherosclerosis."

The ongoing GLOBAL study (ClinicialTrials.gov Identifier NCT01738828) is an international, prospective, multi-center study recruiting up to 7,000 patients to characterize novel disease networks and biomarkers for coronary artery disease (CAD). The study is being funded by G3 and conducted together with strategic partner Health Diagnostic Laboratory. Eligible patients undergo coronary CT angiography providing an accurate and detailed examination of the disease and disease status. This precision phenotyping is combined with a pan-omic analysis, and the data is then analyzed utilizing specifically developed systems biology-based bioinformatics technology for identification of diagnostic biomarkers and potential therapeutic targets.

"The GLOBAL study will involve the collection of 22 trillion data points used to decode the complex biology underlying atherosclerotic disease," said Tonya Mallory, chief executive officer, president and co-founder of Health Diagnostic Laboratory, a strategic partner of G3. "The study will represent validation of this technology and opens the door to similar analyses of other diseases, such as oncologic, neurodegenerative and psychiatric, with the goal of identifying novel biomarkers and therapeutic targets for diagnosis, prevention and treatment of these serious and debilitating diseases."

About Global Genomics Group (G3)

G3 is a life sciences company investigating biological networks that lead to the development of disease to identify novel diagnostic biomarkers and therapeutic targets. G3 combines precision phenotyping with pan-omics (genomics, epigenomics, transcriptomics, proteomics, metabolomics, lipidomics, lipoprotein proteomics and glycomics) and bioinformatics to investigate the development and progression of conditions such as atherosclerosis in cardiovascular disease.

For additional information, please visit www.globalgenomicsgroup.com

About Illumina

Illumina is a leading developer, manufacturer, and marketer of life science tools and integrated systems for the analysis of genetic variation and function. We provide innovative sequencing and array-based solutions for genotyping, copy number variation analysis, methylation studies, gene expression profiling, and low-multiplex analysis of DNA, RNA, and protein. We also provide tools and services that are fueling advances in consumer genomics and diagnostics. Our technology and products accelerate genetic analysis research and its application, paving the way for molecular medicine and ultimately transforming healthcare.

Forward-Looking Statements

This release may contain forward looking statements that involve risks and uncertainties. Important factors that could cause actual results to differ materially from those in any forward-looking statements are detailed in our filings with the Securities and Exchange Commission, including our most recent filings on Forms 10-K and 10-Q, or in information disclosed in public conference calls, the date and time of which are released beforehand. We do not intend to update any forward-looking statements after the date of this release.

G3 Contacts 
Media 
Martina Schwarzkopf, Ph.D. 
(212) 845-4292  
martina.schwarzkopf@russopartnersllc.com

Corporate   
Idean Marvasty
(404) 368-1554
idean.marvasty@globalgenomicsgroup.com

Illumina Contacts  
Investors    
Rebecca Chambers  
(858) 255-5243  
rchambers@illumina.com   

Media     
Jennifer Temple  
(858) 882-6822   
pr@illumina.com


'/>"/>
SOURCE Global Genomics Group (G3); Illumina, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Health Care Equipment & Supplies: Global Industry Guide
2. Sequenom Announces Global Certified Service Provider Program
3. InspireMD Appoints David Blossom as Vice President of Global Marketing and Strategy
4. Global Markets for Emerging Insulin Drug and Delivery Technologies - Focus on Syringes and Vials
5. Global Markets for Contract Pharmaceutical Manufacturing, Research and Packaging - Focus on Contract Packaging
6. Shire to Present at the Bank of America Merrill Lynch Global Health Care Conference
7. Synthetic Biologics to Present at the First Global Life Sciences Conference in Warsaw, Poland
8. Orexigen Therapeutics to Present at the Bank of America Merrill Lynch Global Healthcare Conference
9. Quest Diagnostics to Speak at the Morgan Stanley Global Healthcare Conference
10. Shire to Present at the Morgan Stanley Global Healthcare Conference
11. Arena Pharmaceuticals to Present at the Bank of America Merrill Lynch Global Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... CHAPEL HILL, N.C. , June 24, 2016 ... in healthcare decisions and regulators/payers have placed more ... this new environment, patient support programs in the ... support for patients, medications. Consequently, pharmaceutical companies are ... to ensure they are providing products and services ...
(Date:6/24/2016)... June 24, 2016   Bay Area Lyme ... Dean Center for Tick Borne Illness , ... Rehabilitation, MIT Hacking Medicine, University of California, Berkeley, ... announced the five finalists of Lyme Innovation ... More than 100 scientists, clinicians, researchers, entrepreneurs, and ...
(Date:6/24/2016)... -- The Academy of Managed Care Pharmacy (AMCP) today ... allow biopharmaceutical companies to more easily share health care ... coverage decisions, a move that addresses the growing need ... The recommendations address restrictions in the sharing of product ... a prohibition that hinders decision makers from accessing HCEI ...
Breaking Medicine Technology:
(Date:6/27/2016)... Aliso Viejo, California (PRWEB) , ... June 27, 2016 , ... ... that are fully customizable inside of Final Cut Pro X," said Christina Austin - ... with another unique style. Final Cut Pro X users can now reveal ...
(Date:6/27/2016)... ... June 27, 2016 , ... ... strategic partnership with Connance, a healthcare industry leader providing predictive analytics to ... technology combine to provide health systems, hospitals and ambulatory surgical centers with ...
(Date:6/27/2016)... Park, KS (PRWEB) , ... June 27, 2016 , ... ... in retailers of Eyeglasses . , Millions of individuals in the United States ... eyeglasses have become a way to both correct vision and make a fashion statement. ...
(Date:6/26/2016)... Battle Creek, Michigan (PRWEB) , ... June 26, 2016 , ... ... abuse, joined as sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table ... held in honor of the city’s history as home to some of the world’s ...
(Date:6/26/2016)... ... ... PawPaws brand pet supplements owned by Whole Health Supply is ... of felines. The formula is all-natural and is made from Chinese herbs that have ... Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root Extract ...
Breaking Medicine News(10 mins):