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Global Biosimilars: A return to optimism?
Date:12/12/2012

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TABLE OF CONTENTS

Foreword 1
Executive Summary 3
What is a biologic drug? 4
What's in a name? 5
Biobetters 6
Why are Biosimilars an issue? 7
products in the 'first wave' 8
Erythropoietin (Epoetin, EPO) 8
What is it? 8
Who makes it? 8
Summary sales data 9
Company-specific sales data 13
Procrit/Eprex 13
Epogen/Aranesp 13
Neorecormon/Epogin 15
Current biosimilar activity 16
USA 16
Europe 16
Rest of the world 17
Human Growth Hormone (somatropin) 19
What is it? 19
Who makes it? 19
Summary sales data 20
Company specific sales data 23
Genotropin 23
Humatrope 23
Norditropin/other Novo Nordisk HGH products 24
Nutropin 24
Saizen/Serostim 25
Bio-Tropin/Tev-Tropin 26
Current biosimilar activity 27
USA 27
European Union 27
Rest of the world 27
G-CSF 29
What is it? 29
Who makes it? 29
Summary sales data 29
Company specific sales data 32
Neupogen/Neulasta 32
Neutrogin/Granocyte 33
Leukine 33
Current Biosimilar Activity 34
USA 34
European Union 34
Current biosimilar activity in the rest of the world 35
Human Insulin 37
What is it? 37
Who makes it? 37
Summary sales data 37
Company specific sales data 41
Novo Nordisk recombinant insulin products 41
sanofi-aventis recombinant insulin products: Lantus, Apidra 42
Current biosimilar activity 44
USA 44
European Union 44
Rest of the World 44
Interferon 46
What is it? 46
Who makes it? 46
Summary sales data 46
Company specific sales data 50
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