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Glivec(R) is the First Adjuvant Treatment Approved in the UK to Delay Return of Gastrointestinal Cancer After Surgery
Date:5/7/2009

ost people who have surgery to remove their cancer receive no further preventative treatment.

Glivec is now the only treatment approved to delay the return of this cancer, filling a previously unmet need for GIST patients.

References

1. EMEA opinion http://www.emea.europa.eu/pdfs/human/opinion/Glivec_65949508en.pdf. Last accessed 7 May 2009

2. DeMatteo, R. et al. Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial. The Lancet. Online publication 19/03/09. DOI: 10:1016/S0140-6736(09)60500-6. http://download.thelancet.com/pdfs/journals/lancet/PIIS0140673609605006.pdf?i d=aeaa5a245ca1fddb:3c6bded9:1201d7429fe:-15be1237448848073. Last accessed 14.04.09

3. Van den Abbeele A., Benjamin R., Blanke C, et al. Clinical Management of GIST. Recurrence patterns and prognostic factors for survival. Highlights From the 2003 CTOS Annual Meeting and Helsinki GIST Symposium. http://www.ctos.org/newsletter/GIST_Newsletter0404.pdf, last accessed on 14.04.09

4. Demetri GD, Benjamin RS, Blanke CD, et al. NCCN task force report: management of patients with gastrointestinal stromal tumor (GIST)- update of NCCN clinical practice guidelines. J Natl Compr Cancer Network, 2007; 2(suppl 1):S1-S26.

5. NHS Cancer improvement. Guidelines for the management of gastrointestinal stromal tumours (GISTs). http://www.cancerimprovement.nhs.uk/%5Cdocuments%5Cupper_gi%5Cpathways%5CGIST _Mngmnt7.pdf, last access
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SOURCE Novartis Oncology
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