Navigation Links
GeoVax Vaccine Only 5th AIDS Vaccine Moving to Phase 2 Human Trials

ATLANTA, Feb. 25 /PRNewswire-FirstCall/ -- GeoVax Labs, Inc. (OTC Bulletin Board: GOVX),, an Atlanta based biotechnology company, announced their HIV/AIDS vaccine is one of the select few to move forward into Phase 2a human trials by the HIV Vaccine Trials Network (HVTN), a network supported by the National Institutes of Health (NIH).

GeoVax's AIDS vaccine is believed to be only the fifth [5th] HIV/AIDS vaccine to be selected to move forward into Phase 2a human trials conducted by the HVTN. In contrast, it was approximately HVTN's 65th vaccine evaluated in Phase 1 human trials.

Most recently, GeoVax Senior Vice President of Research & Development, Dr. Harriet Robinson, and President, Don Hildebrand, attended a meeting with key HTVN officials in Seattle, Washington to plan and prepare necessary documents for the next phase of testing of GeoVax's promising HIV/AIDS vaccine, namely Phase 2a human trials designated as Protocol # HVTN 205.

Attended by over 20 HVTN personnel and key GeoVax personnel, this event included individuals instrumental in organizing and implementing human clinical trials designed to evaluate the GeoVax HIV/AIDS vaccine. The newly planned Phase 2 trials are tentatively scheduled to start mid-2008 and will involve up to 500 participants at several locations in the USA.

"We are delighted that our HIV/AIDS vaccine has been selected to move forward into Phase 2 trials. Our vaccine continues to demonstrate the promise of not only being safe but also effective at eliciting potentially protective immune responses," stated Dr Harriet Robinson, Senior Vice President, Research & Development at GeoVax.

"GeoVax is extremely pleased to have passed the significant hurdles required to move into Phase 2 trials. Only a handful of AIDS vaccines have reached the Phase 2 level of clinical evaluation with the HVTN, including the previously failed vaccines of Vaxgen and Merck," stated GeoVax President, Don Hildebrand.

GeoVax has completed two Phase 1 human trials evaluating its AIDS vaccines with excellent results and has three additional human trials currently underway. Due to promising results from these five trials the HVTN is pushing forward with plans for critically important and larger Phase 2 human trials.

GeoVax AIDS vaccine technology and composition are significantly different than the Merck & Co. Inc. AIDS vaccines that recently had their human trials halted due to safety and effectiveness concerns.

About GeoVax Labs, Inc.

GeoVax Labs, Inc. is a biotechnology company, established to develop, manufacture, license and commercialize human vaccines for diseases caused by HIV-1 (Human Immunodeficiency Virus) and other infectious agents. GeoVax's AIDS vaccine technology is covered by 20 issued or filed patent applications. GeoVax HIV/AIDS vaccines are designed to prevent Acquired Immunodeficiency Disease (AIDS), caused by the virus known as HIV-1 and may be effective as therapeutics (treatment of people already infected with AIDS virus). Studies evaluating these vaccines in HIV/AIDS infected individuals are in the planning stage.

GeoVax's core HIV/AIDS vaccine technologies were developed through a collaboration of colleagues at Emory University's Vaccine Center, the National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC) and the GeoVax team.

GeoVax HIV/AIDS vaccines have moved forward in human clinical trials conducted by the HIV Vaccine Trials Network (HVTN] based in Seattle, Washington. The HVTN, funded and supported by the National Institutes of Health [NIH), is the largest worldwide clinical trials program dedicated to the development and testing of HIV/AIDS vaccines. Preclinical work enabling evaluation of GeoVax DNA and MVA vaccines was funded and supported by the National Institute of Allergy and Infectious Diseases (NIAID). The NIH provided additional support to GeoVax AIDS vaccine development program with a $15 million IPCAVD grant awarded in late 2007.

GeoVax DNA & MVA Genetically Engineered HIV/AIDS vaccines:

-- DNA vaccine "primes" immune responses & MVA vaccine "boosts" immune

responses against the AIDS virus

-- Are both genetically engineered vaccines expressing over 50% of the

AIDS virus components in vaccine recipients and can not cause AIDS

-- Protected 22 of 23 (96%) non-human primates against AIDS for over 31/2


-- Are manufactured & tested under GMP/GLP - EMEA (EU) and FDA [USA]


-- Satisfactorily completed 2 earlier HIV/AIDS vaccine Phase 1 human


-- Currently have 3 ongoing Phase 1 Human Trials - 1 was initiated in

2006, 2 in summer 2007

-- Have been demonstrated safe to date in human trials

-- Demonstrate positive anti-HIV immune responses in majority of human

vaccine recipients

-- Are planned for mid 2008 Phase 2 trials based on success in previous

HVTN conducted trials

Safe Harbor Statement: All statements in this news release, not statements of historical fact, are forward-looking statements. These statements are based on expectations and assumptions on the date of this press release and are subject to numerous risks and uncertainties which could cause actual results to differ materially from those described in forward-looking statements. Risks and uncertainties include, but are not limited to, whether: GeoVax can develop and manufacture these vaccines with the desired characteristics in a timely manner, GeoVax's vaccines will be safe for human use, GeoVax's vaccines will effectively prevent AIDS in humans, vaccines will receive regulatory approvals necessary to be licensed and marketed, GeoVax raises required capital to complete vaccine development, there is development of competitive products that may be more effective or easier to use than GeoVax's products, and other factors over which GeoVax has no control. GeoVax assumes no obligation to update these forward-looking statements, and does not intend to do so. Certain matters discussed in this news release are forward-looking statements involving certain risks and uncertainties including, without limitations, risks detailed in the Company's Securities and Exchange Commission filings and report.

SOURCE GeoVax Labs, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. Dr. Harriet Robinson Joins GeoVax Team as V.P. of R & D to Accelerate AIDS Vaccine Trials Program
2. GeoVax Labs, Inc. Selected by Georgia Bio as 2008 Deal of the Year Award Winner in Life Sciences Industry
3. GeoVax Labs, Inc. Selects Financial Relations Board as Investor Relations Counsel
4. GeoVax Labs, Inc. Third Quarter Financial Results and Operational Update
5. Excellent Results Received from GeoVaxs Full-Dose HIV/AIDS Vaccine Trial
6. GeoVax Labs, Inc. Comments on Discontinuance of Mercks HIV Vaccine Trial
7. GeoVax Successful HIV/AIDS Vaccine Trial Data Presented at AIDS Vaccine 2007 Conference
8. New Patent Awarded for Antigen-Sparing Vaccines that Elicit Robust Immunity
9. Hawaii Biotech Receives Allowance to Perform West Nile Vaccine Clinical Trials
10. Celldex Therapeutics Receives Fast-Track Designation for CDX-110, a Novel EGFRvIII Vaccine for Glioblastoma
11. Novavax Announces Favorable Interim Results from Human Clinical Trial for Its Pandemic Influenza Vaccine Program
Post Your Comments:
(Date:6/23/2016)... Calif. , June 23, 2016 Any dentist ... many challenges of the current process. Many of them do ... of the technical difficulties and high laboratory costs involved. And ... to offer it at such a high cost that the ... it. Dr. Parsa Zadeh , founder of ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... Market Analysis 2016 - Forecast to 2022" report to ... report contains up to date financial data derived from varied ... major trends with potential impact on the market during the ... segmentation which comprises of sub markets, regional and country level ...
(Date:6/23/2016)... -- , , , WHEN: , ... , , , LOCATION: , , , Online, with free ... EXPERT PANELISTS:  , , , Frost & Sullivan,s Global Vice President ... Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... is witnessing an exceptional era. Several new demand spaces, such as ...
Breaking Medicine Technology:
(Date:6/25/2016)... ... 2016 , ... Experts from the American Institutes for Research ... June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR experts ... planning, healthcare costs and patient and family engagement. , AIR researchers will be ...
(Date:6/25/2016)... ... ... "With 30 hand-drawn hand gesture animations, FCPX users can easily customize each ... Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures into hand ... select a ProHand generator and drag it above media or text in the Final ...
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published June 14 ... The article goes on to state that individuals are now more comfortable seeking to ... operations such as calf and cheek reduction. The Los Angeles area medical group, Beverly ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her son ... lash out at his family verbally and physically. , “When something upset him, he couldn’t ... would use it. He would throw rocks at my other children and say he was ...
Breaking Medicine News(10 mins):