Navigation Links
Genus Oncology, LLC Announces Initiation of Phase I Trial of GO-203-2c in Patients With Solid Tumors
Date:2/15/2011

VERNON HILLS, Ill., Feb. 15, 2011 /PRNewswire/ -- Genus Oncology, LLC, a clinical-stage company focused on commercializing novel drugs for treatment of cancer, announced it has successfully filed an Investigational New Drug (IND) application with the US Food & Drug Administration (FDA) and has dosed the first patient in a Phase I trial to test its lead compound, GO-203-2c, in patients with solid tumors.

"We are excited to enter this new phase of clinical development," said Stephen Thompson, CEO and President of Genus Oncology. "Filing this IND represents the culmination of years of innovation and hard work by Genus Oncology's scientific and development teams. Our work demonstrates that Mucin 1 (MUC1) is a viable drug target, and that inhibition of MUC1 function blocks tumor development and survival of multiple human cancers in preclinical models, including breast, prostate, colon, lung, and pancreatic cancers. Across multiple animal models of human tumor xenografts, treated animals experienced complete responses and remained tumor free up to 6 months post treatment. We look forward to leveraging our understanding of the role of MUC1 in cancer, and taking the first step to advance the treatment of cancer through Phase I clinical trial and follow-on development programs."

"The basic science behind this is a brilliant piece of work. We are very pleased to translate this into new therapeutics for patients," said Dr. Daniel Von Hoff, Physician in Chief, Distinguished Professor, Translational Genomics Research Institute (TGen), Professor of Medicine, Mayo Clinic, Clinical Professor of Medicine, University of Arizona College of Medicine and Chief Scientific Officer, Scottsdale Healthcare and US Oncology Research, and Principle Investigator for the Phase I study.

The Phase I trial is a prospective, open-label study that is designed to determine the safety and tolerability, and potential anti-tumor activity of Genus' first drug candidate, G
'/>"/>

SOURCE Genus Oncology, LLC
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine technology :

1. US Oncology, Inc. to Exhibit iKnowMed(TM) at the 2009 ASCO EHR Symposium: Harnessing the EHR: From Incentives to Sustainability
2. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
3. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
4. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
5. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
6. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
7. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
8. Xenomics Announces Implementation of its First Diagnostic Test for Acute Myeloid Leukemia Into Clinical Practice
9. Emisphere Technologies, Inc. Announces 2007 Second Quarter Financial Results
10. Amicus Therapeutics Announces Second Quarter 2007 Financial Results
11. Genta Incorporated Announces Second Quarter 2007 Financial Results and Corporate Highlights
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... JERUSALEM , May 23, 2013  Hadasit Bio-Holdings ... portfolio of biotech companies, based on intellectual property ... Israel ,s foremost medical research center, ... Neurosciences Ltd., received significant funding from the Israeli ... Chief Scientist (OCS) to support product development and ...
(Date:5/23/2013)... 23, 2013  Texas, premier physician associations today announced ... survival tools they need to provide demonstrably better and ... care marketplace. "I am confident the Physician ... said Stephen L. Brotherton , MD, ... Texas doctors are determined to make health ...
(Date:5/23/2013)... 2013  Net Medical Xpress Solutions, Inc., (OTC QB: ... the company has signed a letter of intent to ... Huntsville, AL . MedTel Solutions is ... and recruitment of telemedicine physicians. Consideration for the acquisition ... which is expected by June 30, 2013. ...
Breaking Medicine Technology:Hadasit Bio-Holdings Ltd. Portfolio Company - Cell Cure Neurosciences Ltd. Received Additional Government Support 2TMA Launches Physician Services Organization for Patient Care 2TMA Launches Physician Services Organization for Patient Care 3TMA Launches Physician Services Organization for Patient Care 4Net Medical Xpress Announces Acquisition of Telemedicine Staffing Company 2Net Medical Xpress Announces Acquisition of Telemedicine Staffing Company 3
(Date:5/23/2013)... Vegas Hotel Escapes, the premier ... all new vacation packages for the upcoming memorial ... Vegas for this patriotic holiday will be pleased ... VegasHotelEscapes.com's new special pricing available on VegasHotelEscapes.com's website. ... guarantees the lowest prices possible on vacation packages ...
(Date:5/23/2013)... May 23, 2013 If you are ... irritable bowel syndrome (IBS), the food spread this Memorial ... fun. , “While hot dogs and ice cream have ... warm weather months, IBS sufferers often feel the painful ... MD, a gastroenterologist with Lourdes Medical Associates. , IBS ...
(Date:5/23/2013)... (PRWEB) May 23, 2013 Onlinefitnessreview.com recently ... Blast Diet to determine what makes this diet work ... published review highlights three main components of the program: ... a positive mindset and the personal motivation that is ... every 7 days to keep the metabolism rate in ...
(Date:5/23/2013)... By Denise Mann HealthDay Reporter , , THURSDAY, ... of Americans take to help treat hip and knee ... increase risk for developing glaucoma, a small new study ... there is an increase of intraocular pressure (IOP) or ... of the leading causes of blindness. ...
(Date:5/23/2013)... Plano, TX (PRWEB) May 23, 2013 ... the Marketplace , Chaplains have been a part of ... this Memorial Day, like those preceding it, these men ... service to the United States of America. As ... trend of their migration to the workplace chaplaincy world. ...
Breaking Medicine News(10 mins):Health News:Sensitive Stomach? Lourdes Gastroenterologist Advises IBS Sufferers to Think Twice About What They Eat This Holiday Weekend 2Health News:Sensitive Stomach? Lourdes Gastroenterologist Advises IBS Sufferers to Think Twice About What They Eat This Holiday Weekend 3Health News:Onlinefitnessreview.com Publishes 7 Day Belly Blast Diet Review 2Health News:Glucosamine Supplements Tied to Risk of Eye Condition 2Health News:Glucosamine Supplements Tied to Risk of Eye Condition 3Health News:Memorial Day Focus Spotlight on Military Chaplains Transitioning in the Marketplace 2Health News:Memorial Day Focus Spotlight on Military Chaplains Transitioning in the Marketplace 3
... at the NCCN 14th Annual Conference, presented various views on ... experts tackled the spectrum of issues related to defining value, ... of the latest cancer treatments may not warrant their costs. ... rapid growth, both in terms of technological innovation and costs ...
... A small number of products contain allergens no matter what ... News) -- A small number of food products with a ... while about 2 percent of foods products without such a ... offending products more often came from smaller companies, noted the ...
... Fitness Industry Leader Introduces Commercial Grade Cardio Bike ... March 16 Expresso Fitness(R), the leading supplier ... announced the launch of the S3 Upright Youth ... children ages 9-14. The S3 Youth Bike ...
... WASHINGTON, March 16 The African American Health Alliance (AAHA) is ... because of actions by President Barack Obama. In less than two ... improve the health of the American people. His --, ... the Children,s Health Insurance Program Act (CHIP) ensures that more children ...
... day resolution in 2009? Join media mogul Sally Jessy Raphael ... Beres as they take listeners on a journey of seeing ... When you set out to work on your Earth ... upstairs closet, digging through an avalanche of junk should not ...
... STXS ) today announced that it has extended ... of SVB Financial Group (Nasdaq: SIVB ). ... the Company can borrow up to $25 million. "This ... cash position and other financing sources, provides us with the ...
Cached Medicine News:Health News:Experts Weigh in on Controversial Issue of Determining Value of Cancer Care at NCCN Conference 2Health News:Experts Weigh in on Controversial Issue of Determining Value of Cancer Care at NCCN Conference 3Health News:Experts Weigh in on Controversial Issue of Determining Value of Cancer Care at NCCN Conference 4Health News:Experts Weigh in on Controversial Issue of Determining Value of Cancer Care at NCCN Conference 5Health News:Food Allergy Labeling Not Always Accurate 2Health News:Food Allergy Labeling Not Always Accurate 3Health News:Expresso Fitness(R) Launches First Virtual Reality Cardio Bike for Kids 2Health News:African American Health Alliance: On The Road to Health Reform 2Health News:Sally Jessy Raphael Bids Farewell to Her Infamous Red Glasses, Reports Green Nest 2Health News:Stereotaxis Extends Its Credit Facility With Silicon Valley Bank 2Health News:Stereotaxis Extends Its Credit Facility With Silicon Valley Bank 3
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: