Navigation Links
Gentris Corporation Announces Collaboration to Study Blood Stability
Date:7/26/2012

MORRISVILLE, N.C., July 26, 2012 /PRNewswire/ -- Gentris Corporation (www.gentris.com), a global leader in pharmacogenomics and biorepository solutions, announced today that it will begin a collaborative study with a major pharmaceutical company to test the long-term stability of DNA in whole blood samples that have been stored for five and ten years. This study will provide insight into the optimal, long-term storage of clinical samples to ensure adequate DNA integrity for future pharmacogenomics testing.      

The three phase collaboration aims to investigate the effects of multiple freeze-thaw cycles on DNA from whole blood, both fresh and archived. In order to evaluate these effects, DNA will be extracted from archived whole blood samples after several freeze-thaw cycles and will undergo quantitative genotyping for specific genetic variations. Variants were chosen to evaluate both large and small deletions to assess DNA integrity. The results will be compared to genotyping data from the same samples before long-term storage and to similarly treated, freshly collected blood samples. A pharmaceutical partner will provide archived samples and the associated data. Gentris will provide freshly collected samples and perform the genotyping analysis.

The goal of this collaboration is to determine the impact of long term storage and multiple freeze-thaw cycles on the integrity of DNA from whole blood samples. With this data, Gentris will be able to determine whether archived samples would be best stored as whole blood or extracted DNA to ensure sufficient sample quality for future analysis. Maintaining high-quality samples allows pharmaceutical companies to utilize these biospecimens as needed during the entire drug development process, which typically takes several years to complete.

Related Links: www.gentris.com

Quotes: 
"We look forward to collaborating with our pharmaceutical partner to investigate an important question as more companies establish long-term archives of clinical samples," said Eric Hall, Gentris Vice President of Clinical Operations and Biorepository Services. "Because technologies are improving rapidly and the drug development process is lengthy, pharmaceutical companies can gain significant value from reanalyzing samples in order to refine later phases of clinical trials or answer questions that arise during development. Proper handling and storage of samples is the foundation for driving innovation in pharmacogenomics and personalized medicine."

About Gentris Corporation:
Founded in 2001, Gentris is located in Research Triangle Park, NC, where it provides pharmacogenomics and biorepository support for all phases of clinical studies and genomic biomarker programs.  The Company works with academic and industry leaders to translate innovations in pharmacogenomics into safer, more effective medicines, which can lead to accelerated drug development and improvement in patient care globally.  In the past year, Gentris significantly expanded its facility and onsite biorepository to meet the increased needs of biopharma clients, while maintaining a preeminent quality system.  


'/>"/>
SOURCE Gentris Corporation
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Gentris Corporation Partners with the Shanghai Institutes of Preventative Medicine
2. Gentris Corporation Launches New Pharmacogenomics Services
3. Precision Optics Corporation Announces $1 Million Order for Microprecision™ Based Endoscopes
4. CVS Caremark Corporation to Hold First Quarter 2012 Conference Call
5. Richard Wolf Medical Instruments Corporation: 40 Years of Innovation
6. Haemonetics Signs Definitive Agreement to Acquire Pall Corporations Blood Collection, Filtration and Processing Product Lines For $551 Million
7. Luminex Corporation Reports First Quarter 2012 Results
8. ShangPharma Corporation Files 2011 Annual Report on Form 20-F
9. Techne Corporation Releases Unaudited Third Quarter and Nine Month Fiscal Year 2012 Results
10. Without Environmental Hygiene, Hand Hygiene Programs Fall Short in Reducing HAIs in Hospital Settings, Says UMF Corporation
11. Cara Therapeutics Licenses Novel Kappa Opioid Agonist, CR845, to Chong Kun Dang Pharmaceutical Corporation For South Korean Market
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/9/2017)... , June 9, 2017 AirXpanders, Inc. ... focused on the design, manufacture, sale and distribution of ... on the progress of its commercial roll-out in ... available in more than one hundred (100) medical institutions ... AeroForm offers a needle-free alternative for women who ...
(Date:6/7/2017)... -- Endo International plc (NASDAQ: ENDP ) ... Joseph R. Goodwin , U.S. District Court Judge for ... , entered a case management order in MDL 2325, ... Litigation (the "MDL") that includes a provision requiring plaintiffs ... on specific causation within one hundred twenty (120) days ...
(Date:6/3/2017)... June 3, 2017  Eli Lilly and Company ... results from the Phase 3 MONARCH 2 study ... 6 inhibitor, in combination with fulvestrant, significantly improved ... alone in women with hormone-receptor-positive (HR+), human epidermal ... who have relapsed or progressed after endocrine therapy ...
Breaking Medicine Technology:
(Date:6/20/2017)... ... ... As a leading dental practice, Wall Centre Dental supports Stroke Awareness Month ... bleeding gums in Vancouver, BC, may be developing gingivitis, the first stage of ... and diabetes. Drs. Parviz Roshan, Siamak Tehrani and Milton Reskovich offer laser gum therapy ...
(Date:6/20/2017)... ... June 20, 2017 , ... This year, participants in the ... finding product improvements that could reduce the occurrence of unplanned extubations (UEs). ... breathing or to provide medication. Sometimes, patient movement can cause unplanned extubations which ...
(Date:6/20/2017)... ... June 20, 2017 , ... Uniform Advantage ... featuring seven new products designed to create tailored looks and athleisure-inspired outfits. UA Flex ... cotton easy care stretch twill. , With trendy looks hitting the medical community, UA ...
(Date:6/20/2017)... ... , ... John D'Eri, CEO of Rising Tide Car Wash , will ... during the Autism Society of America 's 49th annual conference to be held ... (DJFF) was founded in 2002 as the nation's first autism organization focused exclusively ...
(Date:6/20/2017)... ... June 20, 2017 , ... International water ... The Sharon Kleyne Hour Power of Water, Global Climate Change and Your Health ... world’s water crisis and how it affects the human eyes. , According ...
Breaking Medicine News(10 mins):