Navigation Links
Gentris Corporation Announces Collaboration to Study Blood Stability
Date:7/26/2012

MORRISVILLE, N.C., July 26, 2012 /PRNewswire/ -- Gentris Corporation (www.gentris.com), a global leader in pharmacogenomics and biorepository solutions, announced today that it will begin a collaborative study with a major pharmaceutical company to test the long-term stability of DNA in whole blood samples that have been stored for five and ten years. This study will provide insight into the optimal, long-term storage of clinical samples to ensure adequate DNA integrity for future pharmacogenomics testing.      

The three phase collaboration aims to investigate the effects of multiple freeze-thaw cycles on DNA from whole blood, both fresh and archived. In order to evaluate these effects, DNA will be extracted from archived whole blood samples after several freeze-thaw cycles and will undergo quantitative genotyping for specific genetic variations. Variants were chosen to evaluate both large and small deletions to assess DNA integrity. The results will be compared to genotyping data from the same samples before long-term storage and to similarly treated, freshly collected blood samples. A pharmaceutical partner will provide archived samples and the associated data. Gentris will provide freshly collected samples and perform the genotyping analysis.

The goal of this collaboration is to determine the impact of long term storage and multiple freeze-thaw cycles on the integrity of DNA from whole blood samples. With this data, Gentris will be able to determine whether archived samples would be best stored as whole blood or extracted DNA to ensure sufficient sample quality for future analysis. Maintaining high-quality samples allows pharmaceutical companies to utilize these biospecimens as needed during the entire drug development process, which typically takes several years to complete.

Related Links: www.gentris.com

Quotes: 
"We look forward to collaborating with our pharmaceutical partner to investigate an important question as more companies establish long-term archives of clinical samples," said Eric Hall, Gentris Vice President of Clinical Operations and Biorepository Services. "Because technologies are improving rapidly and the drug development process is lengthy, pharmaceutical companies can gain significant value from reanalyzing samples in order to refine later phases of clinical trials or answer questions that arise during development. Proper handling and storage of samples is the foundation for driving innovation in pharmacogenomics and personalized medicine."

About Gentris Corporation:
Founded in 2001, Gentris is located in Research Triangle Park, NC, where it provides pharmacogenomics and biorepository support for all phases of clinical studies and genomic biomarker programs.  The Company works with academic and industry leaders to translate innovations in pharmacogenomics into safer, more effective medicines, which can lead to accelerated drug development and improvement in patient care globally.  In the past year, Gentris significantly expanded its facility and onsite biorepository to meet the increased needs of biopharma clients, while maintaining a preeminent quality system.  


'/>"/>
SOURCE Gentris Corporation
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Gentris Corporation Partners with the Shanghai Institutes of Preventative Medicine
2. Gentris Corporation Launches New Pharmacogenomics Services
3. Precision Optics Corporation Announces $1 Million Order for Microprecision™ Based Endoscopes
4. CVS Caremark Corporation to Hold First Quarter 2012 Conference Call
5. Richard Wolf Medical Instruments Corporation: 40 Years of Innovation
6. Haemonetics Signs Definitive Agreement to Acquire Pall Corporations Blood Collection, Filtration and Processing Product Lines For $551 Million
7. Luminex Corporation Reports First Quarter 2012 Results
8. ShangPharma Corporation Files 2011 Annual Report on Form 20-F
9. Techne Corporation Releases Unaudited Third Quarter and Nine Month Fiscal Year 2012 Results
10. Without Environmental Hygiene, Hand Hygiene Programs Fall Short in Reducing HAIs in Hospital Settings, Says UMF Corporation
11. Cara Therapeutics Licenses Novel Kappa Opioid Agonist, CR845, to Chong Kun Dang Pharmaceutical Corporation For South Korean Market
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... 2017  Ethicon* today announced the completion of ... held medical device company that manufactures and markets ... treatment of Gastroesophageal Reflux Disease (GERD). This acquisition ... portfolio of minimally invasive options for patients suffering ... of the transaction have not been disclosed. ...
(Date:3/23/2017)... YORK , March 23, 2017 ... sample preparation market is expected to reach USD 7.2 billion ... of 7.1%. Sample preparation is a procedure in which a ... crucial step in most analytical procedures since the methods are ... preparation is one of the most shared procedures in the ...
(Date:3/23/2017)... 2017  Drug diversion is a significant contributing ... overdoses. A new oral fluid monitoring test, announced ... reports more detailed and actionable information to clinicians ... therapy adherence, patient safety, and help to identify ... fluid Rx Evaluation (CORE) system is the first ...
Breaking Medicine Technology:
(Date:3/23/2017)... ... March 23, 2017 , ... After raising more than $1.135 million ($1,479,231 AUD) ... travel pillow in crowdfunding history, has established a U.S. Headquarters in New York ... to Americans. , “We’re excited to be operating on U.S. shores, where most of ...
(Date:3/23/2017)... ... ... conference will prominently feature 150+ Hospital and Health System Executive Speakers including: , ... 43rd President of the United States of America: George W. Bush , ... the Ring: Sugar Ray Leonard , JD, Chairperson, McGuireWoods LLP: Amber McGraw Walsh ...
(Date:3/23/2017)... ... March 23, 2017 , ... Sharon Kleyne, host of the nationally syndicated ... Health on VoiceAmerica, recently talked on her program about how she is looking forward ... remind listeners of an important distinction. World Water Day, Kleyne pointed out, is an ...
(Date:3/23/2017)... ... March 23, 2017 , ... ... help improve all aspects of people’s health and nutrition, announced its product Leyzene ... , Natural Subsistence develops nutritional supplements that help people improve all aspects ...
(Date:3/23/2017)... ... ... Inflow IQ & Inflownomics of Raleigh, NC introduce a powerful information access network. ... experts in dangerous situations the Inflow IQ team can help people. Get ready ... & refreshing knowledge systems that enhance life. , Authentically enjoy 500 ...
Breaking Medicine News(10 mins):