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Genta Clinical Programs Featured in Multiple Abstracts at the Annual Meeting of the American Society of Clinical Oncology

BERKELEY HEIGHTS, N.J., May 21 /PRNewswire-FirstCall/ -- Genta Incorporated (OTC Bulletin Board: GNTA) announced that multiple abstracts featuring its lead oncology products will be featured at the 44th annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago, May 30 - June 3, 2008.

The abstracts include the following:

-- Initial Phase 1 Clinical and Pharmacokinetic Assessment of G4544, an

oral gallium-containing Compound. Poster # 53C Abstract No: 8592

Saturday, May 31, 2008.

-- A Phase I/II Study to Determine the Feasibility and Efficacy of the

Triple Combination of Oblimersen (OBL), Abraxane (ABX), and

Temozolomide (TMZ) in Metastatic Melanoma and Normal LDH. Poster # 16

Abstract No: 9027 Sunday, June 1, 2008.

-- Effect of the Addition of Oblimersen (Bcl-2 antisense) to

Fludarabine/Cyclophosphamide for Relapsed/Refractory Chronic

Lymphocytic Leukemia (CLL) on Survival in Patients Who Achieve CR/nPR:

Five-year Follow-up from a Randomized Phase III Study. Abstract # 7008

Monday, June 2, 2008.

-- Prognostic Impact of Baseline LDH on Survival Independent of Tumor

Burden in Advanced Melanoma: Results of Phase III Trial of

Oblimersen-Dacarbazine (OBL-DTIC) vs. DTIC. (Publication).

-- Short IV Infusion of Oblimersen (OBL) in Patients with Solid Tumors:

Safety and Pharmacokinetics. (Publication).

-- Pharmacokinetics of Albumin-bound Paclitaxel (ABX) in combination with

Temozolomide (TMZ) and Oblimersen Sodium (OBL) in Patients with

Advanced Melanoma. (Publication).

About Genta

Genta Incorporated is a biopharmaceutical company with a diversified product portfolio that is focused on delivering innovative products for the treatment of patients with cancer. Two major programs anchor the Company's research platform: DNA/RNA-based Medicines and Small Molecules. Genasense(R) (oblimersen sodium) Injection is the Company's lead compound from its DNA/RNA Medicines program. Genta is currently recruiting patients to the AGENDA Trial, a global Phase 3 trial of Genasense in patients with advanced melanoma. The leading drug in Genta's Small Molecule program is Ganite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered clinical trials as a potential treatment for diseases associated with accelerated bone loss. The Company is also developing tesetaxel, a novel, orally absorbed, semi-synthetic taxane that is in the same class of drug as paclitaxel and docetaxel. Ganite and Genasense are available on a "named-patient" basis in countries outside the United States. For more information about Genta, please visit our website at:

Safe Harbor

This press release may contain forward-looking statements with respect to business conducted by Genta Incorporated. By their nature, forward-looking statements and forecasts involve risks and uncertainties because they relate to events and depend on circumstances that will occur in the future. Forward-looking statements include, without limitation, statements about:
-- the Company's ability to obtain necessary regulatory approval for

Genasense(R) from the U.S. Food and Drug Administration ("FDA") or

European Medicines Agency ("EMEA");

-- the safety and efficacy of the Company's products or product


-- the Company's assessment of its clinical trials;

-- the commencement and completion of clinical trials;

-- the Company's ability to develop, manufacture, license and sell its

products or product candidates;

-- the Company's ability to enter into and successfully execute license

and collaborative agreements, if any;

-- the adequacy of the Company's capital resources and cash flow

projections, and the Company's ability to obtain sufficient financing

to maintain the Company's planned operations;

-- the adequacy of the Company's patents and proprietary rights;

-- the impact of litigation that has been brought against the Company and

its officers and directors and any proposed settlement of such

litigation; and

-- the other risks described under Certain Risks and Uncertainties

Related to the Company's Business, as contained in the Company's

Annual Report on Form 10-K and Quarterly Report on Form 10-Q.

The Company does not undertake to update any forward-looking statements. There are a number of factors that could cause actual results and developments to differ materially. For a discussion of those risks and uncertainties, please see the Company's Annual Report on Form 10-K for 2007 and its most recent quarterly report on Form 10-Q.


Genta Investor Relations

SOURCE Genta Incorporated
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