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Genomic Health Presents Ten New Studies in Breast, Colon and Prostate Cancers at the American Society of Clinical Oncology (ASCO) Annual Meeting
Date:6/4/2011

er recurrence risk beyond conventional factors, such as tumor grade, number of nodes examined and lymphovascular invasion. Among patients with T3 stage II colon cancers with intact mismatch repair (MMR) protein function for whom conventional factors are uninformative, the Recurrence Score identified 22 percent of patients with an average risk of recurrence at 5 years above 20 percent providing an ability to accurately discriminate recurrence risk not available with conventional prognostic factors. A high colon cancer Recurrence Score reveals an underlying biology indicative of more aggressive disease for which adjuvant therapy may be more appropriately considered.

"These results, emphasizing Oncotype DX's precision, reproducibility and standardization, reinforce the potential value the test can provide for the large subset of stage II colon cancer patients who have T3 tumors which are MMR proficient," said Alan P. Venook, M.D., professor of clinical medicine, Gastrointestinal Oncology Research Program, University of California, San Francisco, and lead investigator of the study.  "Acquiring better understanding of the biology of an individual patient's disease enhances my ability to identify the most appropriate treatment plan for each patient, potentially sparing them from chemotherapy they do not need."

The study, "Validation of a 12-gene colon cancer recurrence score (RS) in patients (pts) with stage II colon cancer (CC) from CALGB 9581" (Abstract #3518) will be presented during a poster discussion on Monday, June 6.

Prostate Cancer:  

Gene Identification Results Support Development of a Prostate Cancer Test to Distinguish Indolent vs. Aggressive Disease

"This year, more than 200,000 men are expected to be diagnosed with prostate cancer, but few will benefit from aggressive treatments," said Eric Klein, M.D., chairman of the Gl
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SOURCE Genomic Health, Inc.
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1. Everist Genomics Announces New Data on OncoDefender™- CRC Test for Predicting Recurrence Risk for Stage I and II Colorectal Cancer Patients
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4. Transgenomic, Inc. Acquires Exclusive Worldwide License to Predictive Markers for Cancer Drug Response
5. Genomic Health Announces Ten Studies Covering Breast, Colon and Prostate Cancers Accepted for Presentation at the American Society of Clinical Oncology (ASCO) Annual Meeting
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10. Rosetta Genomics Announces Issuance of Additional U.S. Patent
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