Navigation Links
Genomic Health Announces Results of Initial Studies to Develop Predictive Tests for Targeted Therapies
Date:5/31/2008

from 734 patients who received at least three to four treatment cycles.

Results showed that in patients with hormone receptor positive disease who had an Oncotype DX Recurrence Score(TM) result greater than 18 (i.e., who were classified as intermediate risk of recurrence or above), a number of candidate genes strongly predicted benefit from treatment with docetaxel (Taxotere), a type of taxane commonly used for breast cancer therapy. A genomic classifier predicting differential benefit was identified and, if validated through additional studies, might be useful in defining differential benefit of docetaxel.

"We continue to gain meaningful insight into the biology of breast cancer and now, possibly, treatment benefit for a common taxane regimen with our ongoing study of the utility of Oncotype DX and additional breast cancer genes," said Lori J. Goldstein, M.D., Director of the Breast Evaluation Center at Fox Chase Cancer Center in Philadelphia, Pennsylvania, and lead author of the study. "Further research to narrow down which genes are most predictive and validate their use could potentially yield a new panel of genes that may predict the benefit of treatment with docetaxel."

About Oncotype DX(R)

Oncotype DX is the first and only multi-gene expression test commercially available that has clinical evidence validating its ability to predict the likelihood of chemotherapy benefit as well as recurrence in early-stage breast cancer. Oncotype DX has been extensively evaluated in multiple independent studies involving more than 3,600 breast cancer patients, including a large validation study published in The New England Journal of Medicine and a chemotherapy benefit study published in the Journal of Clinical Oncology. To date, 7,500 physicians have ordered more than 55,000 tests, and health plans covering over 80 percent of U.S. insured lives provide reimbursement for Oncotype DX through contracts, agreements and policy decisions. Both the Ameri
'/>"/>

SOURCE Genomic Health, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Join NPRs David Ewing Duncan, Author Jessica Queller and a Panel of Medical and Legal Experts in a 90-Minute Webcast on Genetic Testing, Genomic Medicine and Breast & Ovarian Cancer
2. Ipsogen Announces Three Studies at the American Society of Clinical Oncology (ASCO) Meeting Extending the Utility of the Genomic Grade Index for Predicting Response to Chemotherapy in Breast Cancer
3. Rosetta Genomics to Present Multiple Posters at the 44th Annual Meeting of the American Society of Clinical Oncology (ASCO)
4. Transgenomic Establishes Collaboration With the National Cancer Institute to Investigate Mitochondrial Genome and Associated Nuclear Genes in Cancer Cell Lines
5. Rosetta Genomics Signs Agreement With West Coast CLIA Certified Lab to Develop and Validate Tests Applying Companys MicroRNA Technology
6. Columbia University Medical Center and Rosetta Genomics Announce Columbia Universitys Submission of the First Cancer Diagnostic Test Based on Rosetta Genomics Proprietary MicroRNA Technology for Approval to the New York State Department of Health Clinica
7. Transgenomic Announces New Contracts for Phase II Trials With Two Major Pharmaceutical Companies
8. Genomic Health Announces Identification of Genes Associated With Colon Cancer Recurrence Across Multiple Studies
9. Orion Genomics Announces the Discovery of Novel Breast Cancer Biomarkers
10. Genomic Health Announces Eight Oncotype DX(R) Studies to Be Presented at 30th Annual San Antonio Breast Cancer Symposium
11. BiPar Genomic Biomarker Data Demonstrate Overexpression of PARP-1 Gene in Multiple Cancer Types
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2015)... OSAKA, Japan , ... -- ... confirmed,   including Core ... EPS    ... Underlying revenue +6.1% year-to-year (reported revenue growing +8.5% to 446.3 billion yen) ...
(Date:7/29/2015)... , July 29, 2015  Unilife Corporation ("Unilife" or ... a developer, manufacturer and supplier of injectable drug delivery ... strategy that provides the Company with flexibility and control ... Unilife has signed an equity purchase agreement for up ... ("LPC"), a Chicago -based institutional investor, ...
(Date:7/29/2015)... COPENHAGEN, Denmark , July 29, 2015  Ascendis ... biotechnology company that applies its innovative TransCon technology to ... will host a conference call on July 30, 2015, ... results from a Phase 2 pediatric study of once-weekly ... release of the top-line results before the market opens ...
Breaking Medicine Technology:Takeda Reports 1st Quarter Results of FY2015 with Underlying Revenue Growth of +6.1% 2Takeda Reports 1st Quarter Results of FY2015 with Underlying Revenue Growth of +6.1% 3Takeda Reports 1st Quarter Results of FY2015 with Underlying Revenue Growth of +6.1% 4Takeda Reports 1st Quarter Results of FY2015 with Underlying Revenue Growth of +6.1% 5Unilife Announces Multifaceted Financing Strategy 2Unilife Announces Multifaceted Financing Strategy 3Unilife Announces Multifaceted Financing Strategy 4Unilife Announces Multifaceted Financing Strategy 5Ascendis Pharma A/S to Report Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone and Host Conference Call on Thursday, July 30, 2015 at 9:00 a.m. Eastern Time 2
... STXS ) today announced that executive management will ... Tuesday, September 28, 2010 at 8:30 a.m. ET in New ... of the Company,s business strategy and recent corporate developments. ... A live audio and slides webcast of Stereotaxis, presentation may ...
... Instrumentation Laboratory (IL), today announced it will host the ... 2010 at the Grand Hyatt Nusa Dua, in Bali, Indonesia. ... local time.  The forum will focus on the latest clinical ... practicing in the Asia Pacific region are welcome to attend. ...
Cached Medicine Technology:Stereotaxis to Present at the JMP Securities Healthcare Conference 2Stereotaxis to Present at the JMP Securities Healthcare Conference 3Instrumentation Laboratory to Host 2nd Asia Pacific Hemostasis Forum 2Instrumentation Laboratory to Host 2nd Asia Pacific Hemostasis Forum 3Instrumentation Laboratory to Host 2nd Asia Pacific Hemostasis Forum 4
(Date:7/30/2015)... ... July 30, 2015 , ... The American Association ... Rosenberg’s announcement of the reinstitution of National Prescription Drug Take-Back Days. The 10th ... 10:00 AM to 2:00 PM local time. On the 26th, the DEA, with ...
(Date:7/30/2015)... ... July 30, 2015 , ... InventHelp, a leading inventor ... a personal-care device that makes it easy to apply lotion or medication to a ... for assistance when applying lotion or medication to the back, and provides thorough coverage. ...
(Date:7/30/2015)... ... 2015 , ... Political unrest is the number one concern ... survey by leading international insurance provider Clements Worldwide. The "Clements Worldwide Risk Index" ... largest sources of financial losses among respondents. , Twenty-eight percent of top managers ...
(Date:7/30/2015)... , ... July 30, 2015 , ... ... with its Medicare administrative contractor (MAC) over submitted claims for bariatric surgery that, ... a challenge to program integrity, Becky Dennis, a nurse auditor at WellSpan Health, ...
(Date:7/30/2015)... , ... July 30, 2015 , ... At the presentation of the 2015 Annual Meeting ... focused on research presented by the Journal of Arthroplasty pertaining to how soon ... driving. , Results of the study confirm what Santa Rosa Orthopaedics (SRO) ...
Breaking Medicine News(10 mins):Health News:AAPCC Supports National Prescription Drug Take-Back Day 2Health News:AAPCC Supports National Prescription Drug Take-Back Day 3Health News:InventHelp® Client Patents “My Back Buddy” – Device Could Apply Lotion to Hard-to-Reach Areas Easily 2Health News:New Clements Worldwide Global Risk Survey Shows Political Risk and Instability Top Managers' Concerns 2Health News:New Clements Worldwide Global Risk Survey Shows Political Risk and Instability Top Managers' Concerns 3Health News:Hospital Details Fight for Bariatric Surgery Reimbursement in AIS Newsletter 2Health News:Hospital Details Fight for Bariatric Surgery Reimbursement in AIS Newsletter 3Health News:SRO Surgeon Dr. Nathan Ehmer Backs Up Latest Study That Total Hip Replacement Surgery Patients Are Resuming Normal Activities Sooner 2Health News:SRO Surgeon Dr. Nathan Ehmer Backs Up Latest Study That Total Hip Replacement Surgery Patients Are Resuming Normal Activities Sooner 3
... ... of City Dental, offers lifetime teeth bleaching services to new patients , ... Los Angeles (PRWEB) February 22, 2010 -- Leading ... their Free Bleaching for Life services. New patients who visit Dr. Galina for an exam, ...
... ... ... , , , ... ...
... ... ... , ... WASHINGTON , Feb. 22 ...
... ... ... ... ...
... the Sahlgrenska Academy at the University of Gothenburg, Sweden ... the different genetic patterns of neuroblastoma, an aggressive form ... advances in the treatment of this malignant disease, which ... published in the respected scientific journal, Proceedings of ...
... a spotted plaice? Probably. However, marine biologist ,Helen Nilsson ... ,person to research the spotted insides of plaice. ... intricate pigmentation ,patterns, which they use for camouflage, communication, ... A study conducted by ,researchers at the Department of ...
Cached Medicine News:Health News:LA Dentist, Dr. Katherine Galina, Offers Free Bleaching for Life 2Health News:Statewide Poll: Pennsylvania Must Adequately Fund Senior Care Services 2Health News:Statewide Poll: Pennsylvania Must Adequately Fund Senior Care Services 3Health News:Pelosi Statement on President Obama's Health Insurance Reform Proposal 2Health News:International Merchant Advisors CEO Mel Roseman to Discuss New Medical Marijuana Clinics Live on CBS Radio Network's Big Biz Show February 22, 2010 at 1:40 pm PST 2Health News:International Merchant Advisors CEO Mel Roseman to Discuss New Medical Marijuana Clinics Live on CBS Radio Network's Big Biz Show February 22, 2010 at 1:40 pm PST 3Health News:International Merchant Advisors CEO Mel Roseman to Discuss New Medical Marijuana Clinics Live on CBS Radio Network's Big Biz Show February 22, 2010 at 1:40 pm PST 4Health News:New DNA technique leads to a breakthrough in child cancer research 2
Reptilase-Time from Bothrops atrox...
Pefakit PiCT UFH Controls...
Pefakit PiCT LMWH Calibrators...
APTT (Ellagic Acid) - 10 ml...
Medicine Products: