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Genomic Health Announces Results of Initial Studies to Develop Predictive Tests for Targeted Therapies
Date:5/31/2008

- Results from Gene Identification Studies Presented at ASCO Support Further Exploration of Possible Tests to Predict Response to Targeted

Therapies for Colon and Breast Cancers -

REDWOOD CITY, Calif., May 31 /PRNewswire-FirstCall/ -- Genomic Health, Inc. (Nasdaq: GHDX), provider of the Oncotype DX(R) breast cancer assay, today announced results of two separate studies presented at the annual meeting of the American Society of Clinical Oncology (ASCO), that could lead to the development of new tests for predicting benefit from certain targeted therapies in cancer, specifically cetuximab (ERBITUX(R)) for colon cancer and docetaxel (Taxotere(R)) for breast cancer. Oncotype DX is the first and only genomic test that predicts the likelihood of chemotherapy benefit as well as likelihood of disease recurrence for early-stage breast cancer patients.

"These new data represent encouraging results of our work with leading cancer cooperative groups and drug manufacturers to discover and develop genomic tests to determine which patients are likely to benefit from treatment with targeted therapies," said Steven Shak, M.D., chief medical officer of Genomic Health. "We believe this is an important step forward in demonstrating the potential of a diagnostic and therapeutic partnership in advancing the field of personalized medicine."

The first study, "Evaluation of tumor gene expression and K-Ras mutations in formalin-fixed, paraffin-embedded tumor tissue as predictors of response to cetuximab in metastatic colorectal cancer," (abstract 3512) represents the first publicly presented results of Genomic Health's collaboration with Bristol-Myers Squibb and ImClone Systems Incorporated for ERBITUX (cetuximab), a tar
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SOURCE Genomic Health, Inc.
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