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Genomic Health Announces Publication of Study of Oncotype DX(R) in Node-Positive Breast Cancer That Identifies Patients Who Do Not Appear to Benefit From Chemotherapy
Date:12/10/2009

"There are now five studies involving more than 1,000 patients that support the clinical utility of Oncotype DX in guiding treatment selection for node-positive breast cancer," said Steven Shak, M.D., Chief Medical Officer, Genomic Health. "With this suite of clinical evidence, recently expanded Medicare coverage and clinical experience with more than 5,500 patients with node-positive breast cancer, we believe we can arm node-positive patients and their physicians with the same accurate, standardized genomic information that node-negative patients and their doctors have been using to help guide treatment plans over the past five years."

A separate study analyzing how the Oncotype DX Recurrence Score impacts treatment recommendations in breast cancer patients with node-positive disease (Abstract #2031) will be presented at the San Antonio Breast Cancer Symposium on Friday, December 11, 2009 at 7a.m. CST.

About Oncotype DX®

The Oncotype DX breast cancer test is the only multigene expression test commercially available that has clinical evidence validating its ability to predict the likelihood of chemotherapy benefit as well as recurrence in early-stage breast cancer. Additionally, the test report provides quantitative scores for certain individual genes. The Oncotype DX breast cancer test has been extensively evaluated in thirteen clinical studies involving more than 4,000 breast cancer breast cancer patients worldwide, including a large validation study published in The New England Journal of Medicine and a chemotherapy benefit study published in the Journal of Clinical Oncology. As of November 2009, more than 8,000 physicians have ordered more than 120,000 tests in over 50 countries, and both Medicare and private health plans covering over 90 percent of U.S. insured lives, provide reimbursement for Oncotype DX for patients with node-negative
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SOURCE Genomic Health
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