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Genomic Health Announces Publication of Study Using Oncotype DX(R) in Node-Negative and Node-Positive Breast Cancer Patients Treated With Aromatase Inhibitors
Date:3/8/2010

ositive women treated with tamoxifen, it also demonstrated that the established relationship between the RS and risk of distant recurrence for tamoxifen may now be applied to anastrozole. The greater efficacy of anastrozole observed in the parent ATAC trial and the analysis of the RS results in both treatment arms from this study suggests a lower risk of recurrence in patients treated with aromatase inhibitors. Additionally, as consistent with prior OncotypeDX results in node-positive breast cancer, for any RS result, the likelihood of distant recurrence increases with the number of positive nodes.

About Oncotype DX®

The Oncotype DX breast cancer test is the only multigene expression test commercially available that has clinical evidence validating its ability to predict the likelihood of chemotherapy benefit as well as recurrence in early-stage breast cancer. Additionally, the test report provides quantitative scores for certain individual genes. The Oncotype DX breast cancer test has been extensively evaluated in thirteen clinical studies involving more than 4,000 breast cancer patients worldwide, including a large validation study published in The New England Journal of Medicine and a chemotherapy benefit study published in the Journal of
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SOURCE Genomic Health
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