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Genomic Health Announces Data Supporting Use of Oncotype DX(R) to Accurately Assess HER2 Gene Expression in Breast Cancer Patients
Date:9/6/2008

studies. "Oncotype DX's RT-PCR technology for HER2 gene expression employs a large number of controls, which are intended to safeguard against variability in order to ensure a reproducible quantitative result."

Results from an unrelated breast cancer study to evaluate whether new genes, including TOPO2A, might complement the Recurrence Score result and identify individuals more likely to selectively benefit from taxanes were also presented during the ASCO Breast Cancer Symposium.

About Oncotype DX(R)

Oncotype DX is the first and only multi-gene expression test commercially available that has clinical evidence validating its ability to predict the likelihood of chemotherapy benefit as well as recurrence in early-stage breast cancer. Additionally, the test report provides quantitative scores for certain individual genes. Oncotype DX has been extensively evaluated in multiple independent studies involving nearly 4,000 breast cancer patients, including a large validation study published in The New England Journal of Medicine and a chemotherapy benefit study published in the Journal of Clinical Oncology. To date, 7,500 physicians have ordered more than 65,000 tests, and health plans covering over 80 percent of U.S. insured lives provide reimbursement for Oncotype DX through contracts, agreements and policy decisions. Both the American Society of Clinical Oncology (ASCO) and the National Comprehensive Cancer Network recommend the use of Oncotype DX for patients with node-negative breast cancer that is estrogen-receptor positive and/or progesterone-receptor positive. For more information about Oncotype DX, please visit http://www.oncotypedx.com.

About Genomic Health

Genomic Health, Inc. (Nasdaq:

SOURCE Genomic Health, Inc.
Copyright©2008 PR Newswire.
All rights reserved

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