Navigation Links
Genmab Announces Updates on Phase III Cancer Studies
Date:5/29/2008

Updates on Phase III Studies With Ofatumumab, Zalutumumab and Zanolimumab

COPENHAGEN, Denmark, May 29 /PRNewswire-FirstCall/ -- Genmab A/S (OMX: GEN) reports today that the last patient to be included in the planned interim analysis (N=132 patients) in the pivotal Phase III clinical trial of ofatumumab (HuMax-CD20(R)) in refractory chronic lymphocytic leukemia (CLL) has now received the last scheduled treatment.

In order to complete the database and allow for assessment of the responses by an independent committee, the final data will now be collected and analysed with the results expected in early August 2008. Pending a positive outcome, a Biologics License application in this indication is expected to be filed before the end of 2008.

Ofatumumab is an investigational drug being developed to treat CLL, follicular non-Hodgkin's lymphoma, diffuse large B-cell lymphoma and rheumatoid arthritis under a co-development and commercialization agreement between Genmab and GlaxoSmithKline. It is not yet approved in any country.

Genmab also reported that to date, 132 patients have been dosed in the pivotal Phase III study of zalutumumab (HuMax-EGFr(TM)) to treat head and neck cancer patients considered incurable with standard therapy. As survival is the primary endpoint of this study, a planned interim analysis will take place based on the survival data for patients participating in the study. At present, the Company expects this analysis to occur in 2008, but the exact timing cannot be predicted.

In addition, Genmab announced that based on current recruitment rates, despite broadening the inclusion criteria, the Company does not expect the data to be available this year from the ongoing pivotal Phase III study with zanolimumab (HuMax-CD4(R)) in refractory cutaneous T-cell lymphoma patients.

About Genmab A/S

Genmab is a leading international biotechnology company focused on developing fully human antibody therapeutics for un
'/>"/>

SOURCE Genmab A/S
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Genmab A/S - Company Announcement: Novel Insights into HuMax-EGFr Mechanisms of Action Published in PNAS
2. Bionomics Achieves US$1 Million Milestone Payment from Genmab
3. DAHANCA Initiates Head and Neck Cancer Study With Genmabs HuMax-EGFr
4. Kiadis Pharma Announces Collaboration With the Julius Maximilians University of Wurzburg, Germany
5. Alfacell Corporation Announces Preliminary Results From ONCONASE(R) Phase IIIb Clinical Trial
6. BioElectronics Announces Major Clinical Trials
7. Cell Therapeutics, Inc. (CTI) Announces Presentations at American Society of Clinical Oncology (ASCO) Annual Meeting
8. Shire Announces Approval of ELAPRASE(R) (idursulfase) in Brazil
9. Ardea Announces Progress with HIV Non-Nucleoside Reverse Transcriptase Inhibitor Program
10. Novavax Announces Proprietary Method to Create SARS Vaccine and Renewal of NIH Funding for SARS Vaccine Development
11. BARC Announces Long-Term Cooperation In South African Biobanking for HIV Vaccine Trials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... SAN DIEGO , Dec. 18, 2014  RESMED INC. ... report its second quarter of fiscal year 2015 results on ... market close. A press release with ResMed,s results will be ... will host a webcast to discuss operating results and future ... at 1:30 p.m. US Pacific Time and the live webcast ...
(Date:12/19/2014)... , Dec. 19, 2014  Eli Lilly and ... Paris: FR0011184241 – ADOC) today announced a worldwide licensing ... BioChaperone Lispro, for treatment in people with type 1 ... proprietary BioChaperone® technology and is currently in Phase Ib ... Lispro with the goal of optimizing glucose levels during ...
(Date:12/17/2014)... Revenue and earnings above the previous year - ... In the past 2013/14 fiscal year (ended 30 September ... 4.287 billion (last year: EUR 4.190 billion) despite unfavorable currency ... million. "Overall, 2013/14 was a successful fiscal year for the ... CEO of Carl Zeiss AG. "Thanks to our broad portfolio ...
Breaking Medicine Technology:ResMed To Announce Second Quarter 2015 Results 2Lilly and Adocia Announce Alliance to Co-Develop Ultra-Rapid Insulin Based on BioChaperone Technology 2Lilly and Adocia Announce Alliance to Co-Develop Ultra-Rapid Insulin Based on BioChaperone Technology 3ZEISS Asserts its Position in Difficult Environment 2
... Holdings, Inc. ("Bacterin") (OTC Bulletin Board: BIHI ... announced that it launched its OsteoSponge®SC product at the ... taking place February 15-19 in San Diego, CA.  Based ... the Food and Drug Administration to market OsteoSponge®SC as ...
... Feb. 16, 2011 MedAptus®, the market leader ... England Baptist Hospital (NEBH) has selected the company,s ... medicine providers. The NEBH hospitalist team, comprised of ... Inpatient Edition via the web as well as ...
Cached Medicine Technology:Bacterin International to Announce Launch of OsteoSponge®SC at American Academy of Orthopedic Surgeons 2011 Annual Meeting February 15-19 2Bacterin International to Announce Launch of OsteoSponge®SC at American Academy of Orthopedic Surgeons 2011 Annual Meeting February 15-19 3Hospitalists at New England Baptist Hospital Choose MedAptus 2
(Date:12/20/2014)... Francisco, CA (PRWEB) December 20, 2014 ... Social Innovation company just launched first birthday focused portal ... services, “MERRY BIRTHDAY MESSAGE” launched in both US and ... MERRY BIRTHDAY MESSAGE : http://merrybirthday.net/message/ , MERRY ... for everyone’s birthday around the world. , Features, Choose ...
(Date:12/20/2014)... Xarelto bleeding lawsuits filed by men ... and other serious side effects will be consolidated in ... coordinated pretrial proceedings, Wright & Schulte LLC reports. The ... order Friday to transfer 21 Xarelto lawsuits and over ... to the Louisiana district court for coordination by Judge ...
(Date:12/19/2014)... Today, Balfleet.com , a leading ... its formal dress promotion. All the old and new ... off. , Balfleet.com is well-known for its high quality ... dresses, cocktail dresses and more. Its formal dresses are ... and they can create an elegant look when paired ...
(Date:12/19/2014)... Tampa, FL (PRWEB) December 19, 2014 ... Celliant Revitalizing Bedsheets are now available. Celliant, the ... in both sheets and pillowcases. , There are ... clinically proven additional circulation, increased oxygenation and balanced ... quality, faster healing and pain relief; enhanced athletic ...
(Date:12/19/2014)... Canadian, OK (PRWEB) December 19, 2014 ... is home to Lake Eufaula, the state’s largest lake ... lovely lakeside town is home to a little more ... at 1:00 P.M. on Saturday, the 6th of December. ... made its way through downtown Eufaula on Main Street. ...
Breaking Medicine News(10 mins):Health News:Atore, Inc. Releasing the First Birthday Portal 2Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 2Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 3Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 4Health News:Balfleet.com Announces Its Formal Dress Promotion For 2015 2Health News:Energy Textiles Launches Celliant Revitalizing Bedsheets 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 3
... on June 11th, during Games for Health Conference in Boston, MA ... you take care of your brain when every week brings a ... other? Do supplements improve memory? Do you need both physical and ... training approach, if any, is worth your time and money? ...
... New York Hospital Queens One of Clinical Sites, Research Director is ... the world,s most respected medical journals, the New England Journal ... explores treatments for people with both Type 2 diabetes and coronary ... Hospital Queens was one of the sites that conducted this study. ...
... Carl D. Stevens, MD, MPH, a researcher at Los ... BioMed), recently received the Award for Excellence in Education ... at the University of California, Los Angeles (UCLA) established ... excellence in education." Dr. Stevens is a ...
... places where young women outnumber young men, research shows the ... men feel less pressure to settle down as more women ... reach their 30s, the reverse is true and proportionately more ... Daniel Kruger, a University of Michigan researcher who ...
... may meet criteria for full alert, agency says , TUESDAY, ... H1N1 swine flu in Australia may tip the balance and ... flu pandemic since 1968, agency officials said Tuesday. , Cases ... most occurring in the southern state of Victoria. Rapid spread ...
... be key to a restful night, study finds , TUESDAY, ... and having trouble getting a good night,s sleep, you may ... insomnia reported that they slept better after trying meditation, according ... SLEEP, the annual meeting of the Associated Professional Sleep Societies, ...
Cached Medicine News:Health News:First Brain Training Consumer's Guide Debunks Ten Brain Health Myths and Reviews 21 Products 2Health News:First Brain Training Consumer's Guide Debunks Ten Brain Health Myths and Reviews 21 Products 3Health News:First Brain Training Consumer's Guide Debunks Ten Brain Health Myths and Reviews 21 Products 4Health News:First Brain Training Consumer's Guide Debunks Ten Brain Health Myths and Reviews 21 Products 5Health News:Landmark Study Published in New England Journal of Medicine 2Health News:Landmark Study Published in New England Journal of Medicine 3Health News:When young men are scarce, they're more likely to play the field than to propose 2Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 2Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 3Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 4Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 5Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 6Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 7Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 8Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 9Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 10Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 11Health News:Meditation May Help Put Primary Insomnia to Bed 2
... of flexible lighting products. The first is ... different sizes 5", 10", and 15" (refers ... light). These lights are for use in ... ,The second group of flexible lights is ...
Designed to be used for neuromuscular blockage monitoring. Provides for easy placement over the ulnar nerve on a patient's wrist. Dual element permits non-invasive monitoring using a single electrode...
... standby switch maintains power to the instrument without ... pulse/s) , Tetanus: 100 Hz (200 pulses/s) ... Current: Adjustable from 0-70 mA , Stimulus ... Indicators: Battery LED (green) indicates that the units ...
... peripheral nerve stimulator from B. Braun Medical. ... nerve stimulator functionality for over 10 years. ... available, a unique, under-the-glove hand held remote ... Dig. It allows the anesthesia provider operating ...
Medicine Products: