Navigation Links
Genmab Announces Upcoming Ofatumumab Studies
Date:8/25/2008

Front Line CLL, NHL and CLL Retreatment and Japanese Development Studies

Planned

COPENHAGEN, Denmark, August 25 /PRNewswire-FirstCall/ -- Genmab has announced plans to begin four studies of ofatumumab in chronic lymphocytic leukemia and non-Hodgkin's lymphoma.

Genmab A/S (OMX: GEN) announced today plans to begin four studies of ofatumumab in chronic lymphocytic leukemia (CLL) and follicular non-Hodgkin's lymphoma (NHL) this year.

"Genmab and GSK have worked diligently to expand the ofatumumab development program to maximize the value of the antibody for patients and shareholders since our collaboration began," said Lisa N. Drakeman, Ph.D., Chief Executive Officer of Genmab."The new studies we are initiating this year will examine the potential of ofatumumab in Japan as well as a number of new treatment settings - retreatment, maintenance and front line with chlorambucil."

Phase III CLL front line chlorambucil combination This open-label, parallel-arm study will include 444 patients with previously untreated CLL.Patients in the study will be randomized to receive ofatumumab in combination with chlorambucil or chlorambucil alone.Patients receiving ofatumumab in combination with chlorambucil will receive one infusion of ofatumumab at 300 mg, one infusion at 1000 mg a week later, followed by up to 11 monthly infusions at 1000 mg.Patients will be evaluated for disease status one month following last treatment then every 3 months for 5 years.

The primary objective of the study is to evaluate the progression free survival of ofatumumab in combination with chlorambucil therapy versus chlorambucil therapy alone for the treatment of front line CLL.

Phase II CLL ofatumumab retreatment and maintenance treatment study This study will examine the retreatment and maintenance treatment of refractory CLL patients who participated in the ongoing Phase III CLL study and had disease progression following
'/>"/>

SOURCE Genmab A/S
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. DAHANCA Initiates Head and Neck Cancer Study With Genmabs HuMax-EGFr
2. Bionomics Achieves US$1 Million Milestone Payment from Genmab
3. Genmab A/S - Company Announcement: Novel Insights into HuMax-EGFr Mechanisms of Action Published in PNAS
4. Genmab Announces Updates on Phase III Cancer Studies
5. Genmab A/S - Company Announcement Ofatumumab in Subcutaneous Study in Rheumatoid Arthritis Summary: Subcutaneous Administration of Ofatumumab Investigated in Phase I/II Study
6. Genmab Initiates Study of Zalutumumab With Radiotherapy in Head and Neck Cancer
7. Genmab Reaches Milestone in Ofatumumab Collaboration
8. Genmab A/S - Company Announcement: Recruitment Completed In Ofatumumab CLL Front Line Study
9. Genmab and GlaxoSmithKline Announce Positive Top-Line Results in Ofatumumab Chronic Lymphocytic Leukemia Pivotal Study
10. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
11. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2015)... , March 27, 2015  Delcath Systems, Inc. ... medical device company focused on oncology with an ... liver cancers, announces the reporting of data from ... Hydrochloride for Injection with the Delcath Hepatic Delivery ... presentation at the Society of Surgical Oncology (SSO) ...
(Date:3/27/2015)... , March 27, 2015  WebMD Health ... source of health information, today announced an ... National Action Plan for Combating Antibiotic-Resistant ... emphasized the urgency and importance of addressing ... and global health.    The WebMD ...
(Date:3/26/2015)... 2015 /PRNewswire/ - Pivotal Therapeutics Inc. (OTCQX:PVTTF; CSE:PVO), ("Pivotal" or ... on Omega-3 therapies for cardiovascular disease and overall health, ... common shares of the Corporation (the "Common Shares"). The ... of December 5 th , 2014 to March 4 ... is due on or before April 1, 2015. Interest ...
Breaking Medicine Technology:Data Highlighting Delcath's Melphalan/HDS Presented At The Society Of Surgical Oncology Annual Meeting 2Data Highlighting Delcath's Melphalan/HDS Presented At The Society Of Surgical Oncology Annual Meeting 3Data Highlighting Delcath's Melphalan/HDS Presented At The Society Of Surgical Oncology Annual Meeting 4Data Highlighting Delcath's Melphalan/HDS Presented At The Society Of Surgical Oncology Annual Meeting 5Exclusive: WebMD Interviews President Obama About Plan for Combating Antibiotic Resistance 2Exclusive: WebMD Interviews President Obama About Plan for Combating Antibiotic Resistance 3Pivotal Therapeutics announces payment of interest on outstanding convertible notes 2
... Oct. 27 Caraco Pharmaceutical Laboratories, Ltd. (NYSE Amex: ... and $126.4 million for the second quarter and first ... million and $230.5 million, respectively, during the corresponding periods ... lower for the second quarter and first six months ...
... 27 Cumberland Pharmaceuticals Inc. (Nasdaq: CPIX ... financial results before the market opens on Tuesday, November 10, ... be held on Tuesday, November 10, 2009 at 10:00 a.m. ... the call, please dial 888-417-8462 (for U.S. callers) or 719-457-2552 ...
Cached Medicine Technology:Caraco Pharmaceutical Laboratories, Ltd. Reports Results for the Second Quarter and First Six Months of Fiscal Year 2010 2Caraco Pharmaceutical Laboratories, Ltd. Reports Results for the Second Quarter and First Six Months of Fiscal Year 2010 3Caraco Pharmaceutical Laboratories, Ltd. Reports Results for the Second Quarter and First Six Months of Fiscal Year 2010 4Caraco Pharmaceutical Laboratories, Ltd. Reports Results for the Second Quarter and First Six Months of Fiscal Year 2010 5Caraco Pharmaceutical Laboratories, Ltd. Reports Results for the Second Quarter and First Six Months of Fiscal Year 2010 6Caraco Pharmaceutical Laboratories, Ltd. Reports Results for the Second Quarter and First Six Months of Fiscal Year 2010 7Cumberland Pharmaceuticals to Announce Third Quarter 2009 Financial Results on November 10, 2009 2
(Date:3/28/2015)... Take a bite of warm, gooey pepperoni pizza, and ... the stomach, ready to break down your meal. In ... run amok, triggering a burning sensation in the chest. ... million Americans have heartburn at least once a month. ... it can be stopped. , Heartburn or acid reflux ...
(Date:3/28/2015)... Emergency Medical Care (EMC), a New York ... commemorated its three-year anniversary of being the only 24/7 ... 24-hour urgent care, Emergency Medical Care offers its clients ... Emergency Medical Care’s Urgent Care NYC services ... injuries, ear infections, fevers, insect bites, burns, animal bites, ...
(Date:3/28/2015)... Vegas, NV (PRWEB) March 28, 2015 Pitching ... with a history of shoulder and elbow injuries, according to ... Sports Medicine’s ( AOSSM ) Specialty Day. , “Our findings ... with a 20% increase in likelihood of a history of ... associated with a 12% increase likelihood of a history of ...
(Date:3/28/2015)... Early surgery may not be the best ... injuries, according to new research from Tripler Army Medical ... Society for Sports Medicine’s ( AOSSM ) Specialty Day, ... was not performed. , The final study group focused ... 17 receiving non-surgical therapy. Of the non-surgery group, 8 ...
(Date:3/28/2015)... Aureus Medical Group (web: aureusmedical.com), ... therapy jobs, has announced that it will participate ... Association Annual Conference to be held April 10-11, ... Columbus, OH. , The OPTA Annual Conference ... products and services. , Representatives from Aureus ...
Breaking Medicine News(10 mins):Health News:Bypass Your Heartburn Worries This Easter With Tylers Coffee 2Health News:Emergency Medical Care Celebrates Three Years of 24/7 Walk-In Urgent Care Services 2Health News:Researchers Highlight Shoulder and Elbow Injury Possibility in Youth Players 2Health News:For Type V AC Joint Injuries, Early Surgery May Not Be the Best Approach 2Health News:Healthcare Staffing Leader, Aureus Medical Group, to Exhibit at the Ohio Physical Therapy Association Annual Conference 2
... $7,500 for exposing workers to asbestos without warning, ... of,Labor Occupational Safety and Health Administration (OSHA) recently ... asbestos-related,violations. OSHA inspectors found that the hospital put ... "These are serious violations," said Mario Morales, an ...
... HOUSTON, Sept. 24, 2007 -- Rice University scientists have ... a living organism. Using fruit flies, the researchers confirmed ... imaging -- was capable of detecting DNA-sized nanotubes inside ... than living cells, and they give off fluorescent light ...
... activity in adolescents need to cover both school and ... effective, according to a study published today on ... Research Council Epidemiology Unit also found significant positive results ... programmes which along with traditional health education included policy ...
... Spain: Quality of life after treatment for endometrial cancer ... brachytherapy, where radiotherapy is delivered internally using a vaginal ... (Monday September 24). Dr. Remi Nout, from the clinical ... The Netherlands, said that this quality of life benefit ...
... of Maternity(TM), a mini,art gallery within Destination ... is thrilled to present "The Art of ... exhibition. (Photo: http://www.newscom.com/cgi-bin/prnh/20070924/NEM003-a ) ... (Photo: http://www.newscom.com/cgi-bin/prnh/20070924/NEM003-c ) (Photo: ...
... for America,s,Health (TFAH) today announced it has received a ... (RWJF) to continue its,efforts to ensure Americans will have ... health system that serves all,Americans and helps them lead ... to analyze the best research and,build consensus among the ...
Cached Medicine News:Health News:Scientists get first look at nanotubes inside living animals 2Health News:School, family and community involvement are all needed to increase the activity levels of adolescen 2Health News:Internal radiotherapy better than external for quality of life in endometrial cancer patients 2Health News:The Art Of Maternity(TM) at Destination Maternity(R) Presents A Sacred Passage Into Motherhood; the Art of Belly Masking to Belly Casting 2Health News:The Art Of Maternity(TM) at Destination Maternity(R) Presents A Sacred Passage Into Motherhood; the Art of Belly Masking to Belly Casting 3Health News:Trust for America's Health Receives $7.6 Million Grant from the Robert Wood Johnson Foundation to Advance the Quality and Impact of the Public Health System 2
... battery chargers are the ... GENIE blotters. They are ... specific voltages, giving much ... power supplies. 110 volt ...
Inquire...
Inquire...
... PowerPac Universal power supply, 100-120 and 220-240 ... A, and 1-500 W. The two-line, 16-character ... and monitoring of run progress. Built-in infrared ... unit contains a built-in switch when using ...
Medicine Products: