Genetic Differences Predict Anti-Inflammatory Benefits From Nutritiona...( Interleukin Genetics Study Pu...),Health

Interleukin Genetics Study Published in Journal 'Nutrition'

WALTHAM, Mass., Sept. 25 /PRNewswire-FirstCall/ -- Interleukin Genetics (Amex: ILI) reported today in the journal Nutrition that a botanical supplement reduced inflammation more effectively in individuals with genetic variations that are associated with over-expression of inflammation and risk for early heart attacks. This is one of few studies that recruited study subjects who have different genetic patterns and tested how they responded to nutritional products or drugs.

The study examined healthy individuals with raised inflammation levels and their response to a 12-week course of botanical treatment. The study found that patients who tested positive for at-risk IL-1 gene variations were more likely to show a decrease in inflammation after botanical treatment than those who tested negative for the IL-1 gene variations. The genetic test identifies people who tend to over-produce IL-1, a powerful mediator of the inflammatory response, and have an increased risk for early heart attacks. The botanical product used in the study was developed by Access Business Group International LLC (an affiliate of Interleukin's majority stockholder, Alticor Inc.), after screening hundreds of plant extracts in the laboratory for their ability to reduce IL-1 production.

"This study supports the principle of nutritional genetics," said Interleukin President and Chief Scientific Officer Dr. Kenneth Kornman. "In addition to highlighting the successful use of botanicals to reduce certain inflammatory chemicals, patients treated with the same botanicals showed significantly different results based on their genetics. Although several studies have suggested that
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