Navigation Links
Generex and RXi Pharmaceuticals Announce Positive Research Data Using RNAi Technology in the Development of Therapeutic Vaccines for Cancer
Date:1/6/2011

WORCESTER, Mass., Jan. 6, 2011 /PRNewswire/ -- Generex Biotechnology Corporation (www.generex.com) (OTC Bulletin Board: GNBT), together with its wholly-owned immunotherapeutic vaccines subsidiary, Antigen Express, Inc. (www.antigenexpress.com), and RXi Pharmaceuticals Corporation (www.rxipharma.com) (NasdaqCM: RXII), a recognized leader in RNAi-based therapeutics, today announced that they have obtained positive early research data from their collaboration to explore the use of RXi's RNAi technology to develop proprietary vaccine formulations for active immunotherapy.

(Logo: http://photos.prnewswire.com/prnh/20110106/NY25057LOGO-a)

(Logo: http://photos.prnewswire.com/prnh/20110106/NY25057LOGO-b)

Initial results from the collaboration demonstrated success in using RXi's proprietary self-delivering rxRNA™ (sd-rxRNA™) compounds to silence genes up to 80% in hemopoietic cells.  The ability to knock down expression of certain genes in isolated hemopoietic-derived cancer cells (ex vivo) has the potential to convert them into specific immune-stimulants and opens the possibility for development of a new class of anticancer therapeutic vaccines.  RXi's sd-rxRNA compounds may be particularly suitable for this use, since they are able to cross cell membranes without the assistance of any delivery agent.

"We are very pleased to have identified a technology that enables efficient RNAi silencing in hemopoietic cells," said Dr. Eric von Hofe, President of Antigen Express.  "These types of cells are notoriously difficult to deliver RNAi and other oligonucleotide molecules to.  In contrast to other gene silencing technologies, RXi's compounds act more like small molecules, which may greatly facilitate clinical de
'/>"/>

SOURCE Generex Biotechnology Corporation
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related medicine technology :

1. Generex Biotechnology Corporation Initiation Coverage Review Issued By Scimitar Equity, LLC
2. Generex Announces Distribution Agreement for Generex Oral-lyn™ in Chile
3. Generex Announces Presentations of Novel Vaccine Strategies
4. Generex Announces Approval of Adjournment Proposal and Adjourned Special Meeting Date
5. Generex Announces Sales Agreement with Elias Shaker & Company
6. Generex Presents Abstract at EASD Annual Meeting
7. Generex Awarded a New Patent in Canada for its Proprietary Buccal Drug Delivery System
8. Generex Biotechnology Provides a Corporate Update to Address Managements Strategic Initiatives for Growth
9. Generex Reaches Agreement to Acquire 51% Stake in Global Medical Direct, a Nationwide Durable Medical Equipment and Pharmaceutical Provider Specializing in Direct-to-Consumer Diabetes Supplies
10. Generex Provides Clarification for Special Meeting Voting
11. Generex Announces That Adjournment Will be Sole Matter Considered at Reconvened Special Meeting of Stockholders on October 15, 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/18/2013)... 2013 /PRNewswire-iReach/ -- Today E-T-A Circuit Breakers announced ... Module. The X3130, integrated with E-T-A,s double-pole ... appliance inlet module, rocker switch and resettable overcurrent ... allows design engineers to streamline the number of ... by 66 percent - and reduce the overall ...
(Date:6/18/2013)... Mass. , June 18, 2013 ... the company was named Overall Performance Leader in Imaging ... Equipment & Infrastructure report. Philips also received Best in ... its imaging products: Ingenuity Core 128 Computed Tomography ... ultrasound and PageWriter TC70 cardiograph. The annual Best in ...
(Date:6/18/2013)... June 18, 2013 Unilife Corporation ("Unilife" or ... developer and manufacturer of injectable drug delivery systems, today ... www.unilife.com . The new site includes additional products, ... occur on a regular basis. Mr. ... an emerging global leader for injectable drug delivery systems, ...
Breaking Medicine Technology:Three-in-One X3130 Appliance Inlet Module 2Philips Named 2013 Overall Performance Leader In Imaging Equipment By KLAS 2Unilife Launches New Corporate Website 2
... 2011  Ampio Pharmaceuticals, Inc. (Nasdaq: AMPE)("Ampio" or the "Company"), ... previously approved drugs and new molecular entities ("NMEs"), announced ... accredited investors to sell an aggregate approximately 2,220,255 of ... share (the "Shares"), at a price per share of ...
... Radiologic (vRad), a technology-enabled national radiology practice, ... Montgomery Radiology Associates (MRA) have joined its ... Inc. (DII). These former MRA radiologists will ... (PMMC) and join the more than 60 ...
Cached Medicine Technology:Ampio Pharmaceuticals Announces Registered Direct Common Stock Offering of Approximately $9.436 Million 2Ampio Pharmaceuticals Announces Registered Direct Common Stock Offering of Approximately $9.436 Million 3vRad Radiology Alliance Continues to Transform Radiology With Most Recent Practice Partnership 2
(Date:6/19/2013)... Pass, OR (PRWEB) June 19, 2013 To survive ... Navy Pilot and Vietnam veteran Captain W.S. “Bud” Orr, the most ... water. Speaking to host Sharon Kleyne on the Sharon Kleyne Hour ... survival kit in Vietnam, he always placed extra water ahead of ... a weight limit on survival kits that pilots could carry on ...
(Date:6/19/2013)... McGuff Pharmaceuticals, Inc. continues to ... (ANDA) for Hydroxyprogesterone Caproate Injection, USP 250mg/mL, 5mL, multiple ... fomerly known as Delalutin™. We are providing this ... approval and market introduction dates for McGuff’s Hydroxyprogesterone Caproate ... our pending ANDA, to date, McGuff has responded to ...
(Date:6/19/2013)... Calculating insurance rates is a complex process that requires insurance ... course their own company policies. This process is a ... to company, and why by shopping around for the ... as car insurance can be a hefty expense for all ... factors that determine their car insurance premiums. These tips ...
(Date:6/19/2013)... Sudden cardiac arrest can strike anyone, even a ... of 5 minutes after cardiac arrest, but the average emergency ... that death is highly probable if an automated external defibrillator ... In response to this dire reality, US Representative Lois Capps ... (H.R. 2308) which would provide support for AED and CPR ...
(Date:6/19/2013)... (PRWEB) June 19, 2013 Anant Goel, CEO ... and changing rapidly. The first industrial revolution began in Britain ... textile industry… when the factory was born. The second industrial ... mastered the moving assembly line and ushered in the age ... in the 21st century. Manufacturing is going digital and this ...
Breaking Medicine News(10 mins):Health News:Vietnam Navy Pilot Reveals to Radio Host Sharon Kleyne That He Carried Extra Water Not a Gun in Survival Kit 2Health News:Current Progress Towards ANDA Approval of Hydroxyprogesterone Caproate Injection, USP 2Health News:icandrive.ca Provides Tips to Understand the Top Factors That Affect Car Insurance Premiums 2Health News:icandrive.ca Provides Tips to Understand the Top Factors That Affect Car Insurance Premiums 3Health News:AED.com Supports Automated External Defibrillator (AED) Legislation in Schools in US and UK 2Health News:RKNet Studios Announced Cognitions Bridge Intelligence Games for Fun, Cognitive Skills Testing and Development for Success in Life 2Health News:RKNet Studios Announced Cognitions Bridge Intelligence Games for Fun, Cognitive Skills Testing and Development for Success in Life 3Health News:RKNet Studios Announced Cognitions Bridge Intelligence Games for Fun, Cognitive Skills Testing and Development for Success in Life 4
... ... the parts washing industry. Midbrook has extensive experience washing parts and equipment in a variety ... facility to help a North American automotive parts supplier solve a de-rusting issue. , ... (Vocus) October 6, 2009 -- ...
... Michael Pernecky ... ... of access control and photo ID products, today announced the promotion of Michael Pernecky to ... card line as well as working hand in hand with our sales staff in developing ...
... 6 The authors of a newly published ... conclude that the micro-bland embolization technique possible with ... Franco Orsi, MD, PhD, and colleagues at the ... that small, tightly calibrated Embozene(TM) Microspheres are better ...
... HOSPITAL ROOM , New research shows that certain noninvasive ... up to a distance of 1 m from patients ... spread of highly contagious respiratory illness within the hospital ... with mild lung injury, researchers from Hong Kong measured ...
... In response to recent research that shows young athletes ... future neurological problems, the Illinois Athletic Trainers Association (IATA) ... are offering a wallet-sized card with tips for detecting ... parents, coaches and others who work with young athletes ...
... MOORESVILLE, N.C., Oct. 5 With medical identity theft ... has chosen to implement Palm Identify, a software application ... purpose of the new solution is to enhance patient ... , Hugh Chatham Memorial Hospital is a private, not-for-profit ...
Cached Medicine News:Health News:Midbrook Production Washing A Valuable Partner 2Health News:Midbrook Production Washing A Valuable Partner 3Health News:Scientific Paper Supports Micro-Bland Embolization Technique for Liver Cancer With Embozene(TM) Microspheres 2Health News:News briefs from the October issue of Chest 2Health News:New Complimentary Wallet Card to Tackle Concussions 'Head On' 2Health News:Hugh Chatham Adopts Star Trek Technology with the Use of Palm Identify to Prevent Medical ID Theft 2
Fiber optic illumination with XHL xenon halogen illumination. Large-diameter glass viewing window with 3X magnification, airtight window seal and swivelling viewing window....
Designed for instrumentation under magnification. Both lens and speculum can be swivelled. Open construction to allow access and examination under magnification and illumination....
Cost-effective otoscope with xenon halogen illumination. Polycarbonate molded head. Acrylic viewing window with 3X magnification. Nasal and spreadable specula avaliable....
Provides 30% more illumination, high light output for true tissue. Wide-angle viewing lens, sealed system for pneumatic otoscopy....
Medicine Products: