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Generex Provides Corporate Update
Date:8/2/2011

the extant Phase II study.  Results from the ongoing Phase II study will be used for patient number adjustment, thereby assuring statistical significance in the Phase III trial.  Also, the Company recently completed a Phase I study of the AE37 vaccine for prostate cancer and a Phase I study of the AE37 vaccine for ovarian cancer is underway.  AE37 represents a new class of self-potentiating peptide vaccines designed to stimulate the immune system to specifically recognize and kill cancer cells.  
  • Valuation of the AE37 breast cancer vaccine.  Recently, a leading national independent valuation firm specializing in pharmaceuticals prepared an appraisal for the Company's AE37 breast cancer vaccine and arrived at a value of $301 million at the vaccines current stage of clinical development.  Given that Herceptin®, which is only available to treat roughly one-third of the patients that would be eligible for AE37, had sales of $1.8 Billion in 2008, the Company believes the estimated valuation of its breast cancer vaccine to be conservative.  The report did not include or evaluate the potential use of AE37 for treatment of other cancers expressing lower levels of HER2 than are required for use with Herceptin®, such as prostate, ovarian, colon, and lung tumors.  

  • Strengthened Product Pipeline.  In addition to the clinical advancement of Generex Oral-lyn™ and its oncology product pipeline, the Company has been focusing its efforts on leveraging both its RapidMist™ buccal drug delivery technology and it immunotherapeutic vaccine platform by way of partnering with leading research and development companies.  A collaboration with RXi Pharmaceuticals (NasdaqCM: RXII) to explore the use of RXi's RNAi technology to develop proprietary vaccine formulations for active immun
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SOURCE Generex Biotechnology Corporation
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3. Generex Announces Presentations of Novel Vaccine Strategies
4. Generex Announces Approval of Adjournment Proposal and Adjourned Special Meeting Date
5. Generex Announces Sales Agreement with Elias Shaker & Company
6. Generex Presents Abstract at EASD Annual Meeting
7. Generex Awarded a New Patent in Canada for its Proprietary Buccal Drug Delivery System
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