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Generex Provides Corporate Update
Date:8/2/2011

and positive marketing approval. Generex will also focus on studies that will measure Generex Oral-lyn™'s ability to provide metabolic benefits that cannot be achieved with subcutaneously injected insulin such as prolonged reduction of over-production of glucose by the liver.  The additional, added-value, market expansion work will be done concurrently.
  • Reported Positive Clinical Data on Generex Oral-lyn™.  The Company recently provided preliminary results of the Generex Oral-lyn™ 084 Phase III clinical trial in patients with Type 1 diabetes and another study of patients with impaired glucose tolerance (IGT).  The clinical trial 084 in patients with Type 1 diabetes will be closed this month.  Interim results demonstrated that the type 1 patients treated with Generex Oral-lyn™ maintained metabolic control (hemoglobin A1c) over the 12 month duration of the trial.  The clinical study of patients with IGT is the first demonstration of Generex Oral-lyn™'s ability to directly increasing first phase insulin levels and reducing post prandial glucose using a non-invasive therapy, thus the potential to use Generex Oral-lyn™ as a frontline treatment for patients with IGT could have far reaching implications.

  • Advanced Oncology Clinical Programs.    In regard to the on-going Phase II clinical study of Antigen's AE37 novel immunotherapeutic vaccine for the treatment of breast cancer with The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., the Company announced that it will increase patient enrollment from 190 to 330 to ensure good representation of patient populations being considered for the upcoming Phase III trial.  The Company anticipates that a Phase III clinical study of the breast cancer vaccine will be initiated prior to the completion of
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SOURCE Generex Biotechnology Corporation
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