Navigation Links
Generex Points to Potential of Antigen Express Technology Platform beyond Its AE37 Breast Cancer Vaccine
Date:1/31/2013

WORCESTER, Mass. and TORONTO, Jan. 31, 2013 /PRNewswire/ -- Generex Biotechnology Corporation (www.generex.com) (OTCBB: GNBT) today explained the potential of the technology platform used as the basis for its novel breast cancer immunotherapy product AE37. AE37 is currently in late Phase IIb clinical development and has garnered considerable attention based upon favourable results from interim analysis of its controlled, randomized, and blinded trial in women with early stage breast cancer.

The main potential advantage cancer immunotherapy like AE37 has compared to other cancer therapies is the ability to direct the body's immune system against targeted cancer cells, similar to other vaccines that direct the immune system against targeted infections. Obviously, the difficulty in treating cancer this way is that it arises from our own tissues rather than from an outside organism. It requires extra coaxing for the immune system to recognize and attack cancer cells that are similar (relatively on the surface) to a person's normal cells. The proprietary modification that is incorporated into AE37, termed Ii-Key, is what gives AE37 the added potency required to activate and direct the immune system to go after cancer cells. The 'payload' in AE37 is a fragment protein associated with cancer cells, best known in breast cancer, but also known for its occurrence in other cancers, called HER2.

The addition of a protein called Ii-Key, the Antigen Express proprietary technology, to the HER2 fragment ensures that the HER2 target is recognized as the protein to attack by immune cells; additionally, the technology adds the HER2 protein to the immune system memory for future reference. The key activated immune cells, termed CD4+ T helper cells, in a sense represent the Generals of the immune system, controlling and directing the immune system to target key proteins. The proc
'/>"/>

SOURCE Generex Biotechnology Corporation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Generex Announces Presentations of Antigen Express AE37 Breast Cancer Vaccine Data at ASCO 2012
2. Generex Announces New Members of Antigen Express Scientific Advisory Board for the AE37 Breast Cancer Vaccine
3. Generex Augments Antigen Express Scientific Advisory Board
4. Generex Reports on Inaugural AE37 Breast Cancer Vaccine Scientific Advisory Board Meeting
5. Generex Announces OncUView.tv Interviews Featuring the Antigen Express AE37 Breast Cancer Vaccine at ASCO 2012
6. Generex Announces Results of Annual Stockholders Meeting
7. Generex Addresses Recent Trading Volume in Shares of its Common Stock
8. Generex Announces Details of Investor Conference Call
9. Generex Provides an Overview of its Cancer Immunotherapy Product, AE37, and Potential in Early Breast Cancer Given Current and Potential Future Therapies
10. Winner Medicals Special Committee Appoints Independent Financial Advisor and Retains Legal Counsel
11. Pro-Dex, Inc. Appoints Michael J. Berthelot Chief Executive Officer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... 11, 2014 The consumer marketing playbook ... industry sectors to better identify winning tools and ... engage with and understand consumers, as new technologies ... critical purchasing decisions. According to ... one area where organizations can observe a deep ...
(Date:7/11/2014)... , July 11, 2014  Kindred Hospital ... to announce the opening of its new outpatient ... outpatient services to people with chronic, hard to ... which can lead to amputation, lower leg wounds ... have delayed closure, and traumatic injury wounds which ...
(Date:7/11/2014)... LOUIS , July 11, 2014 /PRNewswire/ ... device company, announced today the positive, cost-effective ... its innovative SPiNPerc™ procedure. The SPiNPerc endobronchial ... of a percutaneous approach to biopsy when ... Hospitals, patients and physicians experience positive financial ...
Breaking Medicine Technology:New Technologies Transforming Consumer Marketing Research Playbook 2Kindred Hospital Houston Northwest, With Wound Care Specialists, Opens Outpatient Wound Healing And Hyperbaric Center 2Veran Medical Publishes Lung Cancer Patient Management Study 2
... ... , ATLANTA, Georgia, November 30 ... managed in partnership by MC Strategies/Elsevier and the, University of Minnesota,s ... on "Cerebral Palsy" is now,available for administrators and learners to use as ...
... 30 Middle-aged men and women who engage in high ... their knees and increasing their risk for osteoarthritis, according to ... Radiological Society of North America (RSNA). , "Our data suggest ... greater risk for developing knee abnormalities and, thus, at higher ...
Cached Medicine Technology:Cerebral Palsy Course Strengthens CDS Curriculum as Second Disability Intensive Course Offering 2Cerebral Palsy Course Strengthens CDS Curriculum as Second Disability Intensive Course Offering 3Too Much Physical Activity May Lead to Arthritis 2Too Much Physical Activity May Lead to Arthritis 3
(Date:7/12/2014)... (PRWEB) July 12, 2014 ... & Peripheral Vascular Devices Market by ... Drug-Eluting), Catheter (IVUS, OCT), IVC Filter ... to 2018" analyzes and studies the ... in the U.S. and Canada. , ...
(Date:7/12/2014)... New York, New York (PRWEB) July 12, 2014 ... involving liver damage allegations continue to move forward ... District Court, Eastern District of Pennsylvania, Bernstein Liebhard ... 1, 2014, U.S. District Judge Lawrence F. Stengel ... president. Among other things, Judge Stengel found that ...
(Date:7/12/2014)... Sean Francis, owner of the Kawartha Lakes Fit ... his clients. He’s also known for his support of local non-profits ... to combine the two and is excited to announce that his ... and Girls Club. , The funds are the result of Francis’ ... Francis sent out emails and asked his clients to put out ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 For those who ... bodies can readily absorb the nutrients in food. The enzymes ... that are small enough to be absorbed by human bodies. ... a lack of enzymes in regular food is the cause ... product that was started by Michelle DelPresto, a mother of ...
(Date:7/12/2014)... 2014 Utah Valley Entrepreneurial Forum Top ... awards being bestowed to companies in revenue, and pre-revenue ... community with recognition for new ideas as well as ... revenue. , 25 Under 5 highlights outstanding Utah entrepreneurs ... under 5 years old. Award recipients were recognized at ...
Breaking Medicine News(10 mins):Health News:North American Interventional Cardiology & Peripheral Vascular Devices Market - New Report by MarketsandMarkets 2Health News:North American Interventional Cardiology & Peripheral Vascular Devices Market - New Report by MarketsandMarkets 3Health News:North American Interventional Cardiology & Peripheral Vascular Devices Market - New Report by MarketsandMarkets 4Health News:North American Interventional Cardiology & Peripheral Vascular Devices Market - New Report by MarketsandMarkets 5Health News:Tylenol Lawsuit News: U.S. District Judge Overseeing Federal Tylenol Liver Damage Litigation Orders Deposition of Former McNeil President, Bernstein Liebhard LLP Reports 2Health News:Tylenol Lawsuit News: U.S. District Judge Overseeing Federal Tylenol Liver Damage Litigation Orders Deposition of Former McNeil President, Bernstein Liebhard LLP Reports 3Health News:Tylenol Lawsuit News: U.S. District Judge Overseeing Federal Tylenol Liver Damage Litigation Orders Deposition of Former McNeil President, Bernstein Liebhard LLP Reports 4Health News:Kawartha Lakes Fit Body Boot Camp’s Successful Fat Loss Challenge Results in $2,000 to Boys and Girls Club 2Health News:Kawartha Lakes Fit Body Boot Camp’s Successful Fat Loss Challenge Results in $2,000 to Boys and Girls Club 3Health News:New Super Digestive Enzyme, DZ10, Supercharges The Digestion Process 2Health News:SquareHook is Recognized for UVEF 25 Businesses Under 5 Years-Watch Out 2
... defend title as 238 runners with 33 corporate teams compete ... speed, size, and spirit categories this Sunday, ... Valley Marathon(R) announced today that the field for the third,annual ... 33 corporate teams competing. (Logo: http://www.newscom.com/cgi-bin/prnh/20010807/CMALOGO ) ...
... For millions of Americans the benefits,of aspirin go ... "low dose" aspirin can help prevent one out ... many people on aspirin therapy who take other ... to this report from Bayer at:, http://media.medialink.com/WebNR.aspx?story=34050 ...
... Nov. 2 /PRNewswire-FirstCall/ - The Westaim Corporation,announced today the ... credit line of $12.6 million from a major financial ... and will be secured by the,equivalent value of asset-backed ... announced that it held $19.7 million in ABCP. In,September, ...
... Consumer Behavior Is Focus of,Presentation at Association of ... NEW YORK, Nov. 2 Using,knowledge from neurosciences ... consumers, brains to gauge their response to commercials ... at Lapiz,says there are dangers in looking for ...
... YORK, Nov. 2 Recent outbreaks of,antibiotic-resistant Staphylococcus aureus, more ... A bacteria that healthy people,can carry on the skin or ... cause infections of the skin, in the blood, in the ... a wide range of antibiotics.,While most of these infections are ...
... (Amex: PTN ) today announced that it will ... Healthcare Conference at the New York Palace,Hotel in New ... ET. Carl Spana, Ph.D., President and Chief Executive ... Company,s corporate and,development programs. To access the live audio ...
Cached Medicine News:Health News:Biggest Field Ever to Compete Nov. 4 for 'Fastest Company in Silicon Valley' Title in the Comerica Corporate Challenge at The 2007 Metro Silicon Valley Marathon(R) 2Health News:Biggest Field Ever to Compete Nov. 4 for 'Fastest Company in Silicon Valley' Title in the Comerica Corporate Challenge at The 2007 Metro Silicon Valley Marathon(R) 3Health News:The Westaim Corporation update on status of short-term investments 2Health News:Exploring the Use of Techniques From Neuroscience in Today's Marketing 2Health News:Exploring the Use of Techniques From Neuroscience in Today's Marketing 3
Ernest nucleus cracker extra delicate cross-action serrated paddle shaped jaws for cracking the nucleus through a 2.5 mm incision....
Epilation forceps angled ends size 3.5"....
Forceps, extra delicate, straight....
Jewelers Forceps, delicate, straight....
Medicine Products: