Navigation Links
Generex Announces Interview of MD Anderson's Dr. Elizabeth Mittendorf, Principal Investigator on Company's AE37 Phase IIb Breast Cancer Efficacy Trial
Date:6/12/2013

lares the design, clinical endpoints, and statistical analyses acceptable for FDA approval.

Finally, Dr. Mittendorf pointed to the possible real benefit of combining AE37 with other agents, such as immune checkpoint inhibitors.  In particular, inhibitors of PD-1 (programmed cell death protein 1) or CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) have been shown to essentially take the brakes off the immune system, allowing it to more effectively combat tumor cells in a general way.  As AE37 activates the immune system to specifically attack tumor cells, essentially "stepping on the gas", it is an exciting hypothesis to try combining them.  It should be noted, however, that patients treated with AE37 alone also appear to have "taken the brakes off" the immune system to an extent.

About Generex Biotechnology Corporation

Generex is engaged in the research, development, and commercialization of drug delivery systems and technologies. Generex has developed a proprietary platform technology for the delivery of drugs into the human body through the oral cavity (with no deposit in the lungs). The Company's proprietary liquid formulations allow drugs typically administered by injection to be absorbed into the body by the lining of the inner mouth using the Company's proprietary RapidMist™ device. Antigen Express, Inc. is a wholly owned subsidiary of Generex. The core platform technologies of Antigen Express comprise immunotherapeutic vaccines for the treatment of malignant, infectious, allergic, and autoimmune diseases. Antigen Express has pioneered the use of specific CD4+ T-helper stimulation technologies in immunotherapy. One focuses on modification of peptides with Ii-Key to increase potency, while a second relies on inhibition of expression of the Ii protein. Antigen Express scientists, and others, have shown clearly that suppression of expression of the Ii protein in cancer cells allows for potent stimulation of T-helper cells and p
'/>"/>

SOURCE Generex Biotechnology Corporation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Generex Announces Presentations of Antigen Express AE37 Breast Cancer Vaccine Data at ASCO 2012
2. Generex Announces New Members of Antigen Express Scientific Advisory Board for the AE37 Breast Cancer Vaccine
3. Generex Augments Antigen Express Scientific Advisory Board
4. Generex Reports on Inaugural AE37 Breast Cancer Vaccine Scientific Advisory Board Meeting
5. Generex Announces OncUView.tv Interviews Featuring the Antigen Express AE37 Breast Cancer Vaccine at ASCO 2012
6. Generex Announces Results of Annual Stockholders Meeting
7. Generex Addresses Recent Trading Volume in Shares of its Common Stock
8. Generex Announces Details of Investor Conference Call
9. Generex Provides an Overview of its Cancer Immunotherapy Product, AE37, and Potential in Early Breast Cancer Given Current and Potential Future Therapies
10. Generex Points to Potential of Antigen Express Technology Platform beyond Its AE37 Breast Cancer Vaccine
11. Generex Touts Pipeline Potential of Antigen Express Subsidiary
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/29/2015)... , May 29, 2015  Hologic, Inc. (NASDAQ: ... entered into a new, five-year secured credit agreement consisting ... $1 billion revolving credit facility. Hologic has ... used these proceeds and the Term Loan to pay ... had an aggregate principal amount outstanding of $1.69 billion ...
(Date:5/29/2015)... -- Research and Markets ( http://www.researchandmarkets.com/research/64lx2w/north_america_mri ) has announced ... - Growth, Trends And Forecasts (2014 - 2019)" ... MRI systems market is estimated to increase from the ... 2020 with a CAGR of 2.9% between 2014 and ... open system, closed system and the standing or upright ...
(Date:5/29/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/p37spr/north_america ) ... Open System MRI Market - Growth, Trends And Forecasts ... The key players in the industry are GE ... and Toshiba Medical Systems MRI ... because of its higher sensitivity and use of non-ionizing ...
Breaking Medicine Technology:Hologic Enters into Five-Year Secured Credit Agreement 2Hologic Enters into Five-Year Secured Credit Agreement 3North America MRI Market - Growth, Trends And Forecasts 2014-2019 with GE, Hitachi Medical, Philips Healthcare, Siemens Healthcare & Toshiba Medical Systems Dominating 2North America Open System MRI Market 2014-2019 with GE, Hitachi Medical, Philips Healthcare, Siemens Healthcare and Toshiba Medical Dominating 2
(Date:5/30/2015)... 30, 2015 This year the ... Pulmonary Horizons to offer one of the most diverse ... discuss successful practices to diagnose, treat and manage patients ... Pulmonary Horizons Conference is Interaction with Multidisciplinary Healthcare ... Overall Needs of Patients with COPD," said Brian W. ...
(Date:5/29/2015)... Displays and Exhibits’ has recently aligned with a ... hanging signs ; making what was formerly an elite ... ceiling rigging points at a usual height of 16’-20’ are ... These signs are very unique and more visible than the ... and dismantle labor and rigging the costs far outweigh the ...
(Date:5/29/2015)... 29, 2015 The science of hair ... Angeles thanks to the efforts of internationally recognized hair ... combined ARTAS hair restoration and manual FUE ... procedures available anywhere. , A Follicular Unit Extraction ... harvesting hair follicle grafts from the donor areas of ...
(Date:5/29/2015)... CO (PRWEB) May 29, 2015 ... new addiction, substance abuse, and co-occurring mental health ... and ribbon cutting for the general public on ... 2nd. , The Recovery Village at Palmer Lake ... intensive outpatient programming, utilizing traditional and evidence-based therapies, ...
(Date:5/29/2015)... North Carolina (PRWEB) May 29, 2015 ... confirmed that the newest Red Hot & Blue restaurant at ... business on Thursday, May 7, 2015. “The Red Hot & ... center for 18 years, but we have moved to a ... are now in the middle of all the activities on ...
Breaking Medicine News(10 mins):Health News:Pulmonary Horizons 2nd Annual COPD Conference Miami Hilton Downtown, July 17-19, 2015 Patient Centered Cross-Continuum Education to Improve the Care of Patients with COPD 2Health News:Pulmonary Horizons 2nd Annual COPD Conference Miami Hilton Downtown, July 17-19, 2015 Patient Centered Cross-Continuum Education to Improve the Care of Patients with COPD 3Health News:Displays and Exhibits Announces New Hanging Sign Supplier 2Health News:Los Angeles and Beverly Hills Hair Transplant Doctor Now Combines Robotic Hair Restoration (ARTAS) and Manual FUE Transplants for Maximum Hair Coverage 2Health News:Advanced Recovery Systems Announces the Opening of The Recovery Village at Palmer Lake 2Health News:Red Hot & Blue Restaurant Opens in Cary, North Carolina 2Health News:Red Hot & Blue Restaurant Opens in Cary, North Carolina 3Health News:Red Hot & Blue Restaurant Opens in Cary, North Carolina 4
... team at the Michigan Center for Translational Pathology at the ... aggressive type of prostate cancer that occurs in about 10 ... discovery could lead, possibly within the next few years, to ... variation of prostate cancer. , Previous studies by this group ...
... are morning people function better on tests , , MONDAY, ... are morning people tend to get better grades than ... North Texas researchers. , They had 824 undergraduate students ... habits and daytime functioning, and found that students who ...
... FRANKLIN, Mass., June 9 A new, ... questions by healthcare,professionals about starting-up and managing ... download at:, http://www.safeliftingportal.com/lift-doctor-booklet ., Titled, "Ask ... Answers about,Safe Lifting," the booklet compiles two ...
... USING ELECTRONIC 222 TO ORDER CLASS II ... ... LLC, the leading,provider of outsourced hospital pharmacy I.V. compounded solutions, ... real-time ordering of Schedule II,Controlled Substances versus the more time-consuming ...
... Gay communities such as clubs, bars, events ... light of several key factors, including Internet dating and ... Minnesota research. , In 2007, about 30 HIV prevention ... spanning 14 different countries completed surveys about changes in ...
... 9 The National Center,for Complementary and Alternative Medicine ... launched Time to Talk, an educational,campaign to encourage patients ... health care providers to openly discuss the use of ... diverse medical and health,care systems, practices, and products that ...
Cached Medicine News:Health News:U-M researchers discover traits of aggressive form of prostate cancer 2Health News:U-M researchers discover traits of aggressive form of prostate cancer 3Health News:U-M researchers discover traits of aggressive form of prostate cancer 4Health News:College Night Owls Have Lower Grades 2Health News:Free Safe Lifting Booklet Available to Help Healthcare Professionals Start-Up, Manage a Patient Safe Lifting Program 2Health News:PharMEDium Announces National Rollout of Electronic 222 Ordering Initiative 2Health News:Internet, tolerance spark change in urban gay communities 2Health News:Time to Talk About CAM: Health Care Providers and Patients Need To Ask and Tell 2Health News:Time to Talk About CAM: Health Care Providers and Patients Need To Ask and Tell 3
... a bedside Transfusion Verification System, is ... a patient receives the specific unit(s) ... crossmatched for them. It has the ... nurse through their institution's policy and ...
... care environment by automatically bar code printing and ... The automated process and reliable bar codes help ... all items, including vials, ampules, syringes, IV bags, ... valuable time for pharmacy staff and helps improve ...
... Management system ensures your patients are receiving ... BloodTrack SafeTx uses the AutoPPI™ barcoded wristband ... collection to transfusion. SafeTx checks that the ... need for bedside paperwork and associated transcription ...
wBloodCare™ provides functionality at the bedside to ensure that the correct patient receives the correct blood product....
Medicine Products: