Navigation Links
Generex Announces Interview of MD Anderson's Dr. Elizabeth Mittendorf, Principal Investigator on Company's AE37 Phase IIb Breast Cancer Efficacy Trial
Date:6/12/2013

a proprietary modification that increases its potency.  The studies that were part of this year's ASCO meeting confirm these unique properties.  Dr. Mittendorf was also noted that this vaccine addresses patients with any level of HER2 expression, unlike other HER2-targeted therapies.  Currently, patients with low HER2 expression represent a patient population of significant unmet need (representing 50% of all breast cancers). 

The updates this year built upon interim results of the Company's controlled, randomized Phase IIb clinical trial of AE37 presented at last year's ASCO meeting.  Those presentations demonstrated a clear trend toward reduced relapse in breast cancer patients who had received AE37.  One of the studies this year showed that while some patients developed a hypersensitivity reaction (urticarial response), they appeared to have a stronger all-around immune response to the AE37 vaccine.  Interestingly, no relapses have been observed in this population of patients.  A second presentation demonstrated that repeated AE37 boosters could be safely given to patients to further augment and extend the initial anti-tumor immune response observed with AE37.

The primary efficacy analysis of Phase IIb data from the Antigen Express breast cancer study is expected prior to the end of 2013.  Mark Fletcher, Generex President & Chief Executive Officer, commented: "Based on the outstanding interim results announced at ASCO 2012, we are looking forward to qualitatively similar results with greater statistical robustness when data is evaluated later this year, which will leave Antigen Express well-positioned to secure a partnership for a Phase III trial."  Antigen Express has been encouraged by the US Food and Drug Administration to submit a protocol for the Phase III trial, which the Company is in the process of preparing under the auspices of a Special Protocol Assessment (SPA), whereby the FDA dec
'/>"/>

SOURCE Generex Biotechnology Corporation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Generex Announces Presentations of Antigen Express AE37 Breast Cancer Vaccine Data at ASCO 2012
2. Generex Announces New Members of Antigen Express Scientific Advisory Board for the AE37 Breast Cancer Vaccine
3. Generex Augments Antigen Express Scientific Advisory Board
4. Generex Reports on Inaugural AE37 Breast Cancer Vaccine Scientific Advisory Board Meeting
5. Generex Announces OncUView.tv Interviews Featuring the Antigen Express AE37 Breast Cancer Vaccine at ASCO 2012
6. Generex Announces Results of Annual Stockholders Meeting
7. Generex Addresses Recent Trading Volume in Shares of its Common Stock
8. Generex Announces Details of Investor Conference Call
9. Generex Provides an Overview of its Cancer Immunotherapy Product, AE37, and Potential in Early Breast Cancer Given Current and Potential Future Therapies
10. Generex Points to Potential of Antigen Express Technology Platform beyond Its AE37 Breast Cancer Vaccine
11. Generex Touts Pipeline Potential of Antigen Express Subsidiary
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... , Sept. 23, 2014  As physicians ... to digital communication channels to learn about new ... finding – from a new report by global ... – shows that communicating via a customized mix ... provides the best opportunity to engage with physicians. ...
(Date:9/23/2014)... -- Enable Injections , developer of a novel ... and nearly painless for patients to self-inject large-dose biologic ... named winner of the ,Buzz of BIO Investor Forum, ... Enable is one of only two ,Buzz ... votes in the "Late Stage Leaders" category.  ...
(Date:9/23/2014)... 2014 Avillion LLP, a ... of Jarrod Longcor as Chief Business ... for structuring, negotiating and executing successful strategic alliances, ... providing management and strategic leadership to the organisation. ... team. Mr Longcor brings to Avillion ...
Breaking Medicine Technology:As sales reps see doors close for in-person visits with physicians, digital doors open communication 2As sales reps see doors close for in-person visits with physicians, digital doors open communication 3As sales reps see doors close for in-person visits with physicians, digital doors open communication 4As sales reps see doors close for in-person visits with physicians, digital doors open communication 5Innovative Wearable Injector Developer, Enable Injections, Wins 'Buzz of BIO Investor Forum' 2Avillion Appoints Jarrod Longcor as Chief Business Officer 2
... Intra-Cellular Therapies, Inc. (ITI),today announced it has initiated ... using its drug candidate ITI-722. ITI-722 acts predominantly,as ... important new,approach to the treatment of SMI. Because ... modulatory activities, ITI believes, ITI-722 can be,used not ...
... Research Is a Winning Pursuit, WASHINGTON, Dec. ... L. Trull President, Foundation for Biomedical,Research:, Biomedical ... of pursuit" in 1980 earned Mario Capecchi a ... setback, the Harvard-educated genetics professor,persisted toward his goal. ...
Cached Medicine Technology:Intra-Cellular Therapies Initiates Phase 2 Clinical Trial for Sleep Maintenance Insomnia 2Intra-Cellular Therapies Initiates Phase 2 Clinical Trial for Sleep Maintenance Insomnia 3Intra-Cellular Therapies Initiates Phase 2 Clinical Trial for Sleep Maintenance Insomnia 4Nobel Prize-Winning Discovery 2Nobel Prize-Winning Discovery 3
(Date:9/23/2014)... The Fit Body Boot Camp franchise is known throughout ... and their community outreach. The new Rockville Fit Body Boot ... of the company’s new fitness boot camp in ... is excited about the grand opening, because of the opportunity ... honor the memory of emergency workers who sacrificed their lives ...
(Date:9/23/2014)... 2014 Maturo Medical Weight and ... announced Dr. Lisa Maturo has received certification in ... Worldlink Medical Academy. Dr. Maturo is one of ... this credential. , World-renowned bioidentical hormone replacement ... the rigorous training course, which trained participants in ...
(Date:9/23/2014)... 23, 2014 Wohl Associates ... packaging equipment, has recently taken delivery of used industrial ... include mixers, sheeters, and equipment for producing gnocchi and ... Toresani unit and a La Parmigiana mixer/extruder. With a ... a mixing tank that is 17” wide, 28” long ...
(Date:9/23/2014)... 23, 2014 Hope For The Warriors® ... Celebration to be hosted in Boston, Massachusetts on Sunday, ... Amphitheater. This signature event honors the courage of our ... the fallen. Proceeds from the evening will benefit Hope ... a sense of self, restoring the family unit, and ...
(Date:9/23/2014)... Los Angeles, CA (PRWEB) September 23, 2014 ... launched sales funnel building software application has created a ... commotion surrounding the launch of this new software has ... published an investigative review for her readers. ... such as site design, programming and development can be ...
Breaking Medicine News(10 mins):Health News:Rockville Fit Body Boot Camp Invites Community to Fitness Boot Camp Grand Opening 2Health News:Rockville Fit Body Boot Camp Invites Community to Fitness Boot Camp Grand Opening 3Health News:Doctor Lisa Maturo of Maturo Medical Obtains Expert Certification in BioIdentical Hormone Replacement Therapy from World Link Medical 2Health News:Used Industrial Pasta Machinery Now Available at Wohl Associates 2Health News:Hope For The Warriors Announces Got Heart, Give Hope Celebration in Boston 2Health News:Hope For The Warriors Announces Got Heart, Give Hope Celebration in Boston 3Health News:ClickFunnels 2.0 – Review Of Russell Brunson’s Sales Funnel Building Software Released 2
... Group,Inc. (Amex: QGP ) (http://www.QuantumMD.com ), ... Noel J. Guillama, President &,CEO, will present at ... p.m. (Pacific) on Monday, August 18, 2008 at ... Guillama will give a 23-minute presentation regarding The ...
... a national survey,of adults, 60 percent of Hispanic American ... is the #1 fatal disease among women.,Further, nearly half ... greater than that of Caucasian women. Dania Rich-Spencer, Vice,President ... the Go,Red For Women, founded by the American Heart ...
... getting infected cells to drop their guard according to ... a catalyst to a cancer-busting reaction which calls up an ... Cancer adapts quickly to traditional drugs which attack infected cells ... of defence using ruthenium as a catalyst to a reaction ...
... School of Medicine, Fox Chase Cancer Center and ... that will speed the translation of medical and ... , As part of the agreement, the ... Translational Medicine, based at Temple, to design and ...
... Program to Increase Breast and ... Cervical Cancer Screening Rates, COLUMBIA, ... care guidance company, today announced the,launch of their Women,s Health ... to help increase the,prevention and early detection of breast and ...
... all evidence of disease in selected patients with cancer ... the first published report from an ongoing clinical trial. ... Clinical Cancer Research, (published online August 12) researchers ... targeted radiation therapy had completely controlled all signs of ...
Cached Medicine News:Health News:The Quantum Group to Present at the Noble Financial Equity Conference 2Health News:The Quantum Group to Present at the Noble Financial Equity Conference 3Health News:Temple, Fox Chase and Geisinger create Keystone Institute for Translational Medicine 2Health News:Resolution Health Introduces Women's Health and Wellness Action Campaign 2Health News:Resolution Health Introduces Women's Health and Wellness Action Campaign 3Health News:Resolution Health Introduces Women's Health and Wellness Action Campaign 4Health News:Targeted radiation therapy can control limited cancer spread 2Health News:Targeted radiation therapy can control limited cancer spread 3
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: