Navigation Links
GeneThera Announces it is Set to Begin Commercial Testing for Johne's Disease as Soon as January, 2009.

WHEAT RIDGE, Colo., Nov. 24 /PRNewswire-FirstCall/ -- GeneThera, Inc. (Pink Sheets: GTHR.PK), announces it will soon begin offering its Real Time PCR test for Johne's disease through its Wheat Ridge, Colo. laboratory.

GeneThera is set to begin offering its Johne's disease testing service as soon as January of 2009. According to GeneThera Chairman, Dr. Tony Milici MD, Ph.D., "We expect to be offering our real time PCR test for Johne's disease, called HerdGuard(TM) by the first of the year on a commercial level. We are already receiving inquiries from several companies as to the availability of the service."

The company states that its PCR test is much more accurate and timely than what is commonly available today. There are other PCR tests available, but what makes GeneThera's service different is exactly that... service. According to the company; "the other PCR tests that are available require the purchase of a test kit from one supplier, and then forwarding the collected samples to a completely different company for analyzing. In other words, the customer has to collect the samples (usually fecal) and send the collected samples to a separate approved laboratory for actual testing. This means the customer is responsible for finding the lab, negotiating the cost of the testing, shipping, and retrieving the results. GeneThera's service is all inclusive. Using their trademarked Field Collection System (FCS(TM)), the client collects the sample (blood, milk, fecal, or colostrum), and then returns them to GeneThera's lab for testing and reporting of the results. The results will be available to customers via a secured web page on GeneThera's website. Everything is included in the price from GeneThera. Pricing is expected to be between $25 and $32 per test, and results are typically available within 24-48 hours of receipt of the samples."

According to a recent study, the infected rate of dairy cattle in the US is approximately 22%. That would mean more than 22 million cattle currently carry the disease in the United States. That same study also reported that the cost of the disease to ranchers and industry is between $40 and $227 per animal in a herd. The costs are mostly associated with poor milk production, poor condition of the animal, and loss of weight at weaning of calves

About Johne's disease (Mycobacterium paratuberculosis)

The bacterium that causes Johne's disease is named Mycobacterium paratuberculosis: often the name is abbreviated M. paratuberculosis. Cattle become infected with M. paratuberculosis as calves but often do not develop clinical signs until 2 to 5 yr of age (29). The primary route of infection is through ingestion of fecal material, milk, or colostrums containing M. paratuberculosis microorganisms. Once ingested, M. paratuberculosis survive and replicate within macrophages in the wall of the intestine and in regional lymph nodes. After an incubation period of several years, extensive granulomatous inflammation occurs in the terminal small intestine, leading to malabsorption and protein-losing enteropathy. Cattle shed minimal amounts of M. paratuberculosis in their feces during the sub clinical phase of infection, and yet, over time, this shedding can lead to significant contamination of the environment and an insidious spread of infection throughout the herd.

Diagnosis of paratuberculosis is difficult because of the fastidious growth pattern of the microorganism and because of the paradoxical immune response of the host animal to infection. During the early sub clinical stages of infection, the microorganism elicits a cell-mediated response by the host that can be characterized by strong delayed-type IV hypersensitivity reactions, lymphocyte proliferative responses to mitogens, and production of cytokines by stimulated T lymphocytes. As the disease progresses from sub clinical to clinical stages, the cell-mediated immune response wanes, and a strong humoral response predominates.

About Real Time PCR

Traditionally, PCR is performed in a tube and when the reaction is complete the products of the reaction (the amplified DNA fragments) are analyzed and visualized by gel electrophoresis. However, Real-Time PCR permits the analysis of the products while the reaction is actually in progress. This is achieved by using various fluorescent dyes which react with the amplified product and can be measured by an instrument. This also facilitates the quantization of the DNA. Not only can one tell instantly "what" DNA is present in the sample but also "how much." Quantitative PCR (Q-PCR), as this technique is known, is used to measure the quantity of a PCR product (usually in a real-time PCR procedure). It is the method of choice to quantitatively measure starting amounts of DNA, cDNA or RNA. PCR is therefore often used to determine whether a DNA sequence is present in a sample and the number of its copies in the sample. Another advantage of Real-Time PCR is rapidity of the assay, since it is not necessary to perform electrophoresis or other procedure after the DNA amplification reaction.


GeneThera, Inc. is a molecular biotechnology company located in Wheat Ridge, Colorado. The Company provides genetic diagnostic solutions for the veterinary and agricultural industries with future plans to include the healthcare industry. The Company's proprietary diagnostic solution is based on a genetic expression assay, GES(TM), a protocol designed to function on a highly automated Fluorogenic PCR platform. This platform enables GeneThera to offer tests that are presently not available from other technologies. The GES is designed for a host of individual diseases, the current priorities being Mad Cow disease, Chronic Wasting Disease, E. coli 0157:H7 and Johne's disease, all diseases affecting cattle worldwide. For more information, contact Dr. Tony Milici at 303-463-6371 or Al Goldsmith of The Goldsmith Group LLC at 303-838-4370.

This press release contains forward-looking statements, which are made pursuant to the Safe-Harbor provisions of the Private Securities Litigation Reform Act of 1995. Words such as "intends," "believes," and similar expressions reflecting something other than historical fact are intended to identify forward-looking statements, but are not the exclusive means of identifying such statements. These forward-looking statements involve a number of risks and uncertainties, including the timely development and market acceptance of products and technologies, the ability to secure additional sources of finance, the ability to reduce operating expenses, and other factors described in the Company's filings with the Securities and Exchange Commission. The actual results that the Company achieves may differ materially from any forward-looking statement due to such risks and uncertainties. The Company undertakes no obligation to revise or update any forward-looking statements in order to reflect events or circumstances that may arise after the date of this release.

Dr. Tony Milici 303-463-6371

The Goldsmith Group 303-838-4370

JR Dopkin & Associates 516-884-3200

SOURCE GeneThera, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. Medarex Announces Initiation of Phase 1b Clinical Development Program with MDX-1106 for the Treatment of Cancer
2. Pharmos Announces Clinical Results from Phase 2a Trial of Topical Diclofenac NanoEmulsion Cream
3. Celator(R) Pharmaceuticals Announces Enrollment of First Patient in Phase 2 Study with CPX-351
4. Portola Announces Data Showing Its Anti-Platelet Drug Inhibits Platelets in Clopidogrel (Plavix(R)) Non-Responders
5. ViroPharma Announces Presentation of Cinryze(TM) Data in Acute Treatment of Hereditary Angioedema
6. Alba Therapeutics Announces Enrollment of Its First European Patient in Global Phase IIb Study of Larazotide Acetate for Treatment of Active Celiac Disease
7. Raptor Pharmaceuticals Corp. Announces Positive Phase IIa Clinical Study Results for Convivia(TM) Program
8. Anesiva Announces Adlea ACTIVE-1 Phase 3 Clinical Results, Ceasing of Zingo Commercial Operations and Restructuring
9. Diagenic Announces Launch of First Breast Cancer Gene-Expression Blood Test
10. VIA Pharmaceuticals Announces Positive Results of Phase 2 Studies of VIA-2291 in Patients With Serious Cardiovascular Disease
11. Celladon Announces Presentation of Clinical Data From First-in-Human MYDICAR(R) Trial for Advanced Heart Failure at American Heart Association Scientific Sessions
Post Your Comments:
(Date:11/24/2015)... , 24 de noviembre de 2015 /PRNewswire/ ... Breathing Pacemaker System, se complace anunciar el nombramiento ... consultor clínico.   ... -   --> ... un fisiólogo y consultor en neonatología y cardiología ...
(Date:11/24/2015)... 2015  DILON Diagnostics and GE Healthcare are pleased ... DILON to distribute GE,s Discovery NM750b Molecular Breast Imaging ... this distribution agreement will provide Dilon,s experienced distribution network ... and is considered an initial step in an ongoing ... clinicians and their patients. --> ...
(Date:11/24/2015)... Sectra (STO: SECT B) announces that ... agreement to deploy Breast Imaging PACS in its ... Breast Center a future-proof platform capable of expanding with the ... that Breast Center of Acadiana has entered into ... in its two freestanding imaging centers. This investment will ...
Breaking Medicine Technology:
(Date:11/24/2015)... ... ... Young patients with a wide variety of dental needs can now receive ... who are pediatric dentists in Tucson, AZ . Unlike traditional treatment options that ... minimal discomfort and bleeding to the patient during treatment and the following recovery period. ...
(Date:11/24/2015)... ... ... DMG Productions announced that they will feature Aphria, Inc., in an upcoming episode ... and show times TBA. , Aphria, Inc., is a publicly traded company incorporated under ... medical marijuana pursuant to the Marijuana for Medical Purposes Regulations (the “MMPR”). , Aphria ...
(Date:11/24/2015)... ... November 24, 2015 , ... ... Bolier Reactor System. Brillouin is the developer of renewable energy technologies capable of ... nuclear reactions (“LENR”), announced today that its WET™ and HHT™ Boiler System reactor ...
(Date:11/24/2015)... ... November 24, 2015 , ... American Family Care (AFC), the nation’s ... a holiday pop-up clinic located in Metro Atlanta’s North Point Mall. The clinic is ... different way. The location is scheduled to operate through Dec. 24. , Holiday Pop-Up ...
(Date:11/24/2015)... ... November 24, 2015 , ... Abington Hospital – Jefferson Health ... Quality® Bariatric Surgery Facility for treating individuals living with morbid or extreme obesity. ... available to its members to help them make informed decisions about their healthcare ...
Breaking Medicine News(10 mins):