Navigation Links
Genalyte And Barbara Davis Diabetes Center Collaborate To Advance Multiplexed Antigen Panel For Early Diagnosis Of Type 1 Diabetes
Date:8/15/2013

SAN DIEGO, Aug. 15, 2013 /PRNewswire/ -- Genalyte, Inc. today announced the launch of its Type 1 Diabetes (T1D) antigen panel that runs on the MaverickTM Detection System.  The Genalyte T1D antigen panel is the first multiplexed assay that measures seven autoantibodies associated with the destruction of pancreatic islet cells seen in type 1 diabetes.  In a related development, Genalyte reported that it is collaborating with the Barbara Davis Center for Childhood Diabetes (BDC) at the University of Colorado School of Medicine to further develop and test multiplexed antigen panels for the early detection of T1D.

The Genalyte T1D antigen panel was developed as part of the first phase of a Small Business Innovation Research (SBIR) grant awarded to Genalyte to develop multiplexed assays for the early detection and monitoring of type 1 diabetes.  The $500,000 grant from the National Institute of Diabetes and Digestive and Kidney Diseases also provides support for expansion of the approach to allow autoantibody response profiling by multiple criteria, which is expected to enhance the ability of researchers and clinicians to detect and monitor the development of the disease.

Martin Gleeson, PhD, Chief Scientific Officer of Genalyte, noted, "The pioneering work of Drs. George Eisenbarth and Liping Yu at BDC established assays for the measurement of islet autoantibodies. These rogue elements of the immune system eventually destroy the pancreatic islet cells that produce insulin. The unique capabilities of our Maverick detection platform have the potential to provide researchers and clinicians with tools to detect and track this process from an early stage, when interventions to interrupt the disease process may be feasible."

An estimated three million individuals in the U.S. have T1D, an autoimmune disorder that leads to life-long dependence on insulin injections.  New disease-modifying therapies may have the potential to reduce or stop the destruction of islet cells in patients at risk of developing T1D.  The availability of tools to identify these patients early in the disease process would facilitate the development and use of these preventative therapies.

"We are pleased to offer our innovative T1D antigen panel to diabetes researchers worldwide at the same time that we are working with Dr. Liping Yu and his lab at the Barbara Davis Diabetes Center to expand the utility of the approach," added Dr. Gleeson.  "BDC is a long-time leader in the quest to develop curative therapies for type 1 diabetes, and we are delighted to collaborate with them to develop the tools that may help make this dream a reality."

The Genalyte T1D antigen panel requires only a 2 to 5 ul serum or plasma sample and provides results in less than 15 minutes, without the use of dyes, fluorescent probes or radioactive labels.  The T1D panel measures autoantibodies to insulin, proinsulin, GAD 65, GAD 67, IA-2 (PTPRN, ICA512), phogrin (PTPRN2, IA-2beta) and ZnT8 (SLC30A8).  For more information, visit http://genalyte.com/maverick-type-1-diabetes-t1d-assay-kit/.Other commercially available tests for the Maverick Detection System include MT-ADA, ENA 4, ENA 6 and ANA 14 assay kits.  Additionally, Genalyte offers researchers a Custom Spotting Service that loads proteins supplied by customers, such as antibodies, peptides, biomarkers, cytokines and antigens, on to standard-format Genalyte chips that are ready to be run on the Maverick System.

Maverick assays are currently available for research use only.

About the Barbara Davis Center for Childhood Diabetes (BDC)
BDC specializes in type 1 diabetes research and care for children and adults. It is one of the largest diabetes institutes in the world. Clinicians, clinical researchers and basic biomedical scientists work at the BDC to prevent and cure type 1 diabetes and to find the most effective treatments. The Center is managed as a distinct administrative unit of the University of Colorado School of Medicine and has a dedicated building on the University of Colorado Anschutz Medical Campus in Aurora, Colorado.  For more information, visit http://barbaradaviscenter.org.About Genalyte
Founded in 2007, Genalyte, Inc. is commercializing the MaverickTM Detection System based on the company's revolutionary Microring Sensor Technology™, a new approach to multiplexing that uses a silicon chip containing arrays of photonic ring sensors to reduce or eliminate sample preparation and provide scalable multiplexing for both proteins and nucleic acids. The one-step workflow of the Maverick System can deliver accurate results in as little as 15 minutes from small volume samples of many types.  It has a large dynamic range and excellent sensitivity with outstanding reproducibility.  For more information, visit www.genalyte.com.Contacts: Genalyte, Inc.

Media:Martin Gleeson, PhD

BLL Partners, LLC Chief Scientific Officer

Barbara Lindheim +1 858 750-4470

+1 212 584-2276 martin@genalyte.com

blindheim@bllbiopartners.com


'/>"/>
SOURCE Genalyte, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Genalyte Awarded $500,000 SBIR Grant To Develop Multiplexed Assays For Early Detection And Monitoring Of Type 1 Diabetes
2. Genalyte Announces CE Mark For Maverick(TM) Detection System And Signs On First European Distributors
3. Congresswoman Barbara Lee Visits Tethys Bioscience
4. Omeros Responds to Misleading Announcement by Davis Wright Tremaine Concerning Settlement with Former Chief Financial Officer
5. Allscripts Congratulates Dr. Davis Lee, Winner of the 2013 Association of Medical Directors of Information Systems (AMDIS) Award
6. Lexicon Receives Funding for Phase 2 Clinical Trial of LX4211 in Type 1 Diabetes
7. Lilly Sets Date for Lilly Diabetes Pipeline Update to the Investment Community
8. Islet Sciences Announces Exclusive License Agreement with Yale University to Commercialize an Early Beta Cell Destruction and Diabetes Diagnostic
9. CASiGEN Pharma Receives A World-wide Exclusive License From GIBH To Bring New Potential Diabetes Treatments To The Global Market
10. Lilly Diabetes Presents Phase II Blood Pressure and Heart Rate Data on Investigational GLP-1 Analog Candidate, Dulaglutide, in Patients with Type 2 Diabetes at the 27th American Society of Hypertension Scientific Meeting
11. Valeritas Inc. Selects dLifes New Diabetes Patient Engagement Solution For Valeritas V-go Disposable Insulin Delivery Device
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/22/2017)... Colo. , Feb. 22, 2017  Aytu BioScience, ... global commercialization of novel products in the field of ... team to up to 42 account managers from 35 ... The sales force expansion is being ... prescriptions and revenues, an indication of increasing acceptance of ...
(Date:2/22/2017)... PUNE, India , February 22, 2017 According ... (Spectroscopy, Chromatography), Measurement (On-Line, In-Line, At-Line), Products and Services (Analyzers, Probes & ... to 2021", published by MarketsandMarkets, the global market is poised to reach ... a CAGR of 13.3% from 2016 to 2021. ... ...
(Date:2/22/2017)... Feb. 22, 2017  CVS Pharmacy is the first ... partially hydrogenated oils (PHO), the primary source of artificial ... store brands food products. The retailer now offers over ... from artificial trans fats. This comes a year and a ... of June 2018 for processed foods to be reformulated ...
Breaking Medicine Technology:
(Date:2/22/2017)... ... February 22, 2017 , ... ... the country today, as organizations, advocates, and individuals join together to increase recognition ... access to ultimately save lives. , “Today we mark a nationwide movement to ...
(Date:2/22/2017)... ... February 22, 2017 , ... Becker’s Spine Review, the ... featuring Michigan neurosurgeon Jay Jagannathan, M.D., as a “Spine Surgeon to Know.” ... neurosurgeons in Michigan performing minimally invasive back surgery that often results in less ...
(Date:2/22/2017)... ... February 22, 2017 , ... Michael J. ... media platform connecting healthcare technology professionals and other key stakeholders with an array ... publication starting on March 1, announced Michael J. Hennessy, Jr., president of MJH ...
(Date:2/22/2017)... ... 2017 , ... Super-Sod will attend the Athens Home Show with a brand ... shift from Super-Sod’s simple Athens Home Show booth of 2016, this year’s exhibit space ... manager Chris Roquemore constructed furniture from recycled pallet wood at the Super-Sod farm in ...
(Date:2/22/2017)... ... February 22, 2017 , ... ... who suffer from combat-related PTSD. , Established in 1977, our organization was at ... challenges of military returning to civilian life were evident and served as the ...
Breaking Medicine News(10 mins):