Navigation Links
Genaera Corporation Presents Promising Preclinical Type 2 Diabetes Data for Trodusquemine (MSI-1436) at Keystone Symposia
Date:1/24/2008

New data supports recent IND and forms foundation for upcoming clinical

programs

PLYMOUTH MEETING, Pa., Jan. 24 /PRNewswire-FirstCall/ -- Genaera Corporation (Nasdaq: GENR) announced today a poster presentation of preclinical data on trodusquemine (MSI-1436), Genaera's lead drug candidate for the treatment of type 2 diabetes and obesity, during the Diabetes Mellitus, Insulin Action and Resistance Keystone Symposia in Breckenridge, Colorado.

Genaera research scientists concluded that treatment with MSI-1436 leads to marked improvement in glucose tolerance and lowers plasma insulin levels in diet-induced obese (DIO) mice and improves fasting blood glucose and glucose tolerance in hyperglycemic animal models, and that these effects are maintained over time. In one study, the researchers reported that four weekly treatments of MSI-1436 administered to DIO mice resulted in significant reductions in plasma insulin levels. Additionally, hyperglycemic (Ob/Ob) mice treated with weekly doses of MSI-1436 for 122 days demonstrated that the significant improvements in glucose tolerance, as measured by oral glucose tolerance testing can be sustained during long periods of therapy. The scientists concluded that the anti-diabetic properties of MSI-1436 included improved insulin sensitivity, lowering of plasma insulin levels and durable improvements in fasting blood glucose and glucose tolerance.

"This encouraging preclinical work continues to provide strong basic science support and direction for our efforts to explore MSI-1436 as a therapy for type 2 diabetes," stated Jack Armstrong, President and Chief Executive Officer of Genaera. "With our recent investigational new drug (IND) filing for type 2 d
'/>"/>

SOURCE Genaera Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Genaera Corporation Presents Interim Phase 1 Data for Obesity Compound Trodusquemine (MSI-1436) at IBC Conference
2. MacroChem Acquires Rights to Pexiganan, a Novel Topical Anti-Infective for Treatment of Diabetic Foot Infections, From Genaera
3. Genaera Corporation Presents Preclinical Trodusquemine (MSI-1436) Data at the North American Association for the Study of Obesity Annual Meeting
4. Genaera Corporation Presents Phase 1 Data for Trodusquemine (MSI-1436) at the North American Association for the Study of Obesity Annual Meeting
5. Genaera Corporation Provides Highlights of Positive Phase 1 Trodusquemine (MSI-1436) Data from the North American Association for the Study of Obesity Annual Meeting
6. Genaera Begins Dosing Second Phase 1 Trial of Type 2 Diabetes and Obesity Compound Trodusquemine (MSI-1436)
7. Genaera Announces Diabetes IND In Effect for Trodusquemine (MSI-1436)
8. CEL-SCI Corporation Releases Letter to Shareholders
9. Alfacell Corporation to Present at UBS Global Life Sciences Conference
10. Baxa Corporation Extends Global Reach With New Distribution Agreements in Colombia and the Dominican Republic
11. The Quigley Corporation Reports Third Quarter Results, Increases Investment in Pharmaceutical R&D for Diabetic Neuropathy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... , September 2, 2014 , ... patients, quality of life and treatment satisfaction [ ... ]        ... 2014, 02 September 2014, Barcelona, Spain ... the PREvention oF thromboembolic events-European Registry in Atrial Fibrillation ...
(Date:9/2/2014)... Utah , Sept. 2, 2014 /PRNewswire-iReach/ -- Ortho ... the Alpine™ Hip Stem, the latest addition to ... Hip Stem is intended for use in total ... - http://photos.prnewswire.com/prnh/20140830/141676 Alpine ... hip stem philosophy. ODEV,s engineers worked closely with ...
(Date:9/2/2014)... RALEIGH, N.C. and ,S-HERTOGENBOSCH, the ... Europe ( http://www.healthlinkeurope.com ) has expanded its North American ... 100% medical facility, providing warehousing, fulfillment and order to ... North America , utilizing our global ERP platform. ... since 1994 serving our customers in Europe ...
Breaking Medicine Technology:One Year Data from the PREFER in AF Registry Show Significant Changes in Atrial Fibrillation (AF) Management in Europe and Implementation of Clinical Guidelines 2One Year Data from the PREFER in AF Registry Show Significant Changes in Atrial Fibrillation (AF) Management in Europe and Implementation of Clinical Guidelines 3One Year Data from the PREFER in AF Registry Show Significant Changes in Atrial Fibrillation (AF) Management in Europe and Implementation of Clinical Guidelines 4One Year Data from the PREFER in AF Registry Show Significant Changes in Atrial Fibrillation (AF) Management in Europe and Implementation of Clinical Guidelines 5One Year Data from the PREFER in AF Registry Show Significant Changes in Atrial Fibrillation (AF) Management in Europe and Implementation of Clinical Guidelines 6One Year Data from the PREFER in AF Registry Show Significant Changes in Atrial Fibrillation (AF) Management in Europe and Implementation of Clinical Guidelines 7One Year Data from the PREFER in AF Registry Show Significant Changes in Atrial Fibrillation (AF) Management in Europe and Implementation of Clinical Guidelines 8Ortho Development Receives FDA Clearance for Alpine Hip Stem 2HealthLink Europe opens North American medical warehouse operation 2
... Inc. (NYSE: SMA ), a leading global ... surgical instruments, and sterilization cases and trays, announced today ... Olsen Medical. Olsen Medical is a privately-held, ... electrosurgical instruments and accessories. It manufactures a full line ...
... 2011 Pharmaceutics International, Inc. (Pii), a leading ... has successfully completed the first-ever US-based joint European ... (FDA) inspection.   "Our entire team ... the joint FDA/EMA inspection," said Tony Horton, vice ...
Cached Medicine Technology:Symmetry Medical Closes Olsen Medical Acquisition 2Pharmaceutics International, Inc. (Pii) Successfully Completes EMA and FDA Inspection 2
(Date:9/2/2014)... Recently, iFitDress.com, a famous online supplier ... released its range of 2014 seashell wedding dresses ... low prices. A large proportion of them are priced ... iFitDress.com are carefully made by the most skilled workers. ... party gowns, ivory satin wedding gowns, white halter wedding ...
(Date:9/2/2014)... September 03, 2014 Recently, Top ... hosting companies and announced that JustHost ( http://www.justhost.com/track/seohosts ... the webmasters. , “The hosting suppliers we recommend ... their competitors on hosting features, uptime and server ... 10 Best SEO Hosting says. “We believe that ...
(Date:9/2/2014)... Friendship Village of Schaumburg is proud to ... contemporary marketing presence and visually solidifies the relationship ... Senior Options,” said Stephen A. Yenchek, president and ... logo, we are making sure that our identity ... families.” , Friendship Village is a retirement community ...
(Date:9/2/2014)... The Wm. Jennings Bryan Dorn Veterans Affairs ... hall meeting for Veterans and their families on September 24. ... to provide Veterans with valuable healthcare and benefit information,” said ... provide a forum where we can gather important input directly ... fair will be held 4:45 p.m. to 5:45 p.m. in ...
(Date:9/2/2014)... followed by radiation therapy survived as long as ... large study conducted by researchers at the Stanford ... Institute of California. , The comprehensive analysis of ... the first to directly compare survival rates following ... (the removal of both breasts), unilateral mastectomy (the ...
Breaking Medicine News(10 mins):Health News:Discounted Seashell Wedding Dresses Currently Provided By iFitDress.com 2Health News:Friendship Village of Schaumburg In Illinois Announces New Logo 2Health News:Breast cancer patients with bilateral mastectomy don't have better survival rates 2Health News:Breast cancer patients with bilateral mastectomy don't have better survival rates 3Health News:Breast cancer patients with bilateral mastectomy don't have better survival rates 4
... Osteoporosis, wherein the density of the bone is lost and ... after they attain their menopause. This happens as a result ... the bone density. ,Dr. Sunil J. Wimalawansa, of the ... study using the animal model that Vitamin E may prevent ...
... women is on the rise. But the alarm bells are ... smokers with breast cancer face an increased risk of their ... nonsmokers ,"There is a relationship between smoking and ... MD, associate professor of medicine at the University of California ...
... is associated with loss of libido, low motivation and ... their menopause or whose ovaries had been removed surgically ... effective treatment in such sexual dysfunction, according to a ... American Urological Association in Anaheim, California. This report was ...
... the current New England Journal of Medicine that an experimental ... men suffering from hemophilia. This method shows signs of ... clotting protein they lack. None of the patients suffers ... ,The study was designed only to test the safety and ...
... be the latest mantra of Pfizer. The pharmaceutical giant ... 50 countries hardest hit by the AIDS virus. The decision ... South African Government winning a landmark case against pharmaceutical companies. ... antifungal drug Diflucan will be given free of cost to ...
... Azad Medical College, New Delhi has created history of ... from the American patent office for his technique in ... ,A few weeks ago the American patent office granted ... was able to regenerate organs like the uterus, urethra ...
Cached Medicine News:
The Freedom Clear catheter is a 100% latex-free, self-adhering, one piece catheter with an ultra-thin sheath for every day wear....
Freedom Clear® SS Sport Sheath is a 100% latex-free, self-adhering, one piece catheter with an ultra-thin sheath designed for everyday wear. Its brief sheath minimizes roll at the base of the p...
... clear, all-silicone Foley catheters eliminate patient ... Foley catheter designs. As an inert, ... creating a safe, dependable Foley catheter. ... all-silicone catheters will not leach chemicals ...
... stone manipulation and removal in ... strength permits the basket to ... than standard flat-wire designs. The ... one-handed operation. Supplied sterile in ...
Medicine Products: