Navigation Links
Genaera Corporation Presents Interim Phase 1 Data for Obesity Compound Trodusquemine (MSI-1436) at IBC Conference
Date:8/19/2007

Interim Phase 1 Data Confirms Safety and Tolerability

PLYMOUTH MEETING, Pa., Aug. 8 /PRNewswire-FirstCall/ -- Genaera Corporation (Nasdaq: GENR) today announced interim data from the first Phase 1 clinical study of trodusquemine (MSI-1436) for the treatment of obesity. Anthony DelConte, M.D., Vice President, Clinical Research and Development, presented "Trodusquemine: A Novel Aminosterol for the Treatment of Obesity and Related Metabolic Disorders," during the IBC 12th Annual World Congress on Drug Discovery & Development of Innovative Therapeutics, August 6-8 in Boston.

The presentation summarized the clinical trial design of the single ascending dose Phase 1 study of MSI-1436 to evaluate safety and pharmacokinetics of the drug in healthy obese volunteers. Dr. DelConte provided interim data from the initial cohorts in the double-blind, randomized, placebo-controlled trial which included safety and pharmacokinetic (PK) data from 20 treated subjects and eight vehicle controls in four sequential dose groups. According to Dr. DelConte, PK profiles from the study thus far show a predictable pattern with minimal subject-to-subject variability and linearity across the range of doses studied. To date, no serious adverse events have been reported. It was emphasized that further study is needed to establish dose limiting toxicity and proof-of-concept in humans.

"These initial findings validate the preclinical safety and PK work done by Genaera scientists. We are encouraged by these findings and will continue to further characterize the safety profile and provide proof of concept for trodusquemine in obesity and type 2 diabetes management," commented Jack Armstrong, President and CEO. "We anticipate a
'/>"/>

SOURCE Genaera Corporation

Copyright©2007 PR Newswire.

Page: 1 2 3 4

Related medicine technology :

1. Genaera Presents Preclinical Data on Trodusquemine (MSI-1436) for the Treatment of Obesity at the American Diabetes Association 67th Scientific Session
2. Genaera to Present Preclinical Data on Trodusquemine for the Treatment of Obesity at the American Diabetes Association 67th Scientific Sessions
3. Alfacell Corporation to Present at C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
4. Millipore Corporation Announces New ReNcell Data from Collaboration with ReNeuron
5. NanoBio Corporation Announces Positive Phase 1 Clinical Results for Topical Treatment for Onychomycosis
6. Alba Therapeutics Corporation Reports Preliminary Phase IIa Clinical Trial Results for AT-1001 for the Treatment of Celiac Disease
7. EpiCept Corporation to Present New NP-1 Data at American Pain Society Meeting
8. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
9. European Society for Medical Oncology (ESMO) Presents Data from the Clinical Trial of MediGenes Cancer-Killing Virus in Press Conference
10. Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity and Safety Profile of Quadramet at International Myeloma Workshop
11. SemBioSys Presents Positive Insulin Data at the American Diabetes Association Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2015)... YORK , April 21, 2015 EpiCast ... Summary Sepsis is a life-threatening complication arising from ... the infection damages its own tissues and organs. Anyone ... among children <1 year of age, older ... 2014). Global estimates for the year 2013 showed that ...
(Date:4/21/2015)... -- Inmark,s acquisition of Saf-T-Pak last week positioned Inmark ... Division 6.2.  For over 25 years, Saf-T-Pak has ... on IATA, ICAO, US DOT, Transport Canada, RID/ADR ... were particularly interested in Saf-T-Pak,s proprietary Learning Management ... programs," said David Oyler , Inmark President ...
(Date:4/21/2015)... , 21. April 2015  CorTechs ... die quantitative Analyse des Hirnvolumens freut sich, ... weltweiten Pharmaunternehmen, bekannt geben zu können. Die ... NeuroQuant-Quantifizierungsreports des Hirnvolumens zusammenarbeiten, der die Identifizierung, ... in Patienten mit multipler Sklerose als Ziel ...
Breaking Medicine Technology:EpiCast Report: Sepsis - Epidemiology Forecast to 2023 2EpiCast Report: Sepsis - Epidemiology Forecast to 2023 3Inmark's Acquisition Of Saf-T-Pak Results In Expansion Of Its Dangerous Goods Training Portfolio 2CorTechs Labs kündigt Partnerschaft für die Bereitstellung umfassender Lösungen zur Quantifizierung des Verlustes von Hirnvolumen bei multipler Sklerose an 2
(Date:4/21/2015)... Danvers, MA (PRWEB) April 21, 2015 ... managed mobility services, has been recognized by the Boston ... Massachusetts. The ranking was announced at a recent ... Journal’s annual list of the fastest-growing private companies in ... held businesses in the state that recorded the fastest ...
(Date:4/21/2015)... The report “Dermatitis – ... on the therapeutic development for Dermatitis. ... new targets and MOAs to produce first-in-class ... is available @ http://www.rnrmarketresearch.com/dermatitis-pipeline-review-h1-2015-market-report.html . ... involved in the therapeutic development for Dermatitis ...
(Date:4/21/2015)... CA (PRWEB) April 21, 2015 Edward ... and Arthur “A.G.” Kawamura, former Secretary of the California ... featured speakers for the 2nd Annual GrowRIVERSIDE Conference: The ... , The inclusion of these nationally known experts ... experts, city planners, farmers and others slated to speak ...
(Date:4/21/2015)... Chicago, IL (PRWEB) April 21, 2015 ... the online retailer known for innovation at its healthiest, ... supplements starting May 1st. , At Wojo Nutrition, they’ve ... health seekers with convenient solutions tailored to meet their ... designed to be blended with any beverage, has been ...
(Date:4/21/2015)... (PRWEB) April 21, 2015 Carinsuranceshoppingsource.com ... of analyzing comprehensive auto insurance plans . ... it provides coverage for numerous situations. The coverage limit ... expensive. Comprehensive auto insurance will protect a car against ... , Comparing quotes is no longer difficult and ...
Breaking Medicine News(10 mins):Health News:Wireless Analytics Ranked as 25th Fastest Growing Private Company in Massachusetts 2Health News:Dermatitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 2Health News:Dermatitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 3Health News:Dermatitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 4Health News:USDA Under Secretary, former CA Agriculture Director to Address 2nd Annual “GrowRIVERSIDE” Conference in June 2Health News:USDA Under Secretary, former CA Agriculture Director to Address 2nd Annual “GrowRIVERSIDE” Conference in June 3Health News:Wojo Nutrition Announces their Lines of Single Serving Liquid Vitamins will be Available for Purchase online at Abesmarket.com Beginning in May 2Health News:Comprehensive Auto Insurance Is An Important But Complex Policy 2
... supplying 150,000 HIV sufferers with free anti-retroviral drugs by the end ... on Monday . ,"We are close to 110,000 people ... of December when we launch a massive scale-up of the drugs" ... increase would be underwritten by a new batch of funding from ...
... bird flu at the weekend, taking the death toll in the ... official said Monday . ,Indonesia has seen its toll ... first confirmed human deaths occurred here. ,"A boy who ... being positively infected," Ningrum, from the ministry's National Bird Flu Information ...
... Dengue fever killed 30 people in Myanmar in the first six ... latest country in the region to experience a surge in ... ministry official, told the weekly Myanmar Times newspaper that the number ... of this year there have been about 3,000 cases of the ...
... into a skin-care product that would wipe away wrinkles and ... ,The government's team of camel researchers, which has already pioneered ... found cosmetic properties in the hardy mammal's milk. ... a hospital's skin department to study it on 20 people ...
... Scientists at Childrens National Medical Center have demonstrated conclusively ... are instrumental in myelination and remyelination, processes essential to ... , This groundbreaking discovery in mouse models ... enhance healthy brain development and/or brain disease repair in ...
... will only make real breakthroughs in childrens medicine if they ... ,Professor John Warner was speaking today at the ... solely devoted to paediatric clinical research. ,The unit ... Marys Hospital, and it is based next to the hospitals ...
Cached Medicine News:Health News:Indonesia Confirms 81st Bird Flu Death 2Health News:Specific Protein is Instrumental in Myelination 2Health News:Specific Protein is Instrumental in Myelination 3Health News:Experts Need to Include Children in Research 2
... 1-step, hand-held, point-of-care device for the qualitative detection ... The TOX/See device can detect up to ... 3 to 8 minutes and requires only a ... individually packaged to maximize convenience and ease of ...
... is a whole blood formulation designed ... of the most popular glucose meters. ... using a control matrix that closely ... packaged in ready-to-use dropper vials with ...
... the laboratory to verify automatic pipets without purchasing ... Each PVS kit contains six vials of Receiver ... Solution. Using the pipet or dilutor to be ... kit is then returned to Streck for analysis ...
... Cyto-Chex BCT is a vacuum tube ... whole blood samples for immunophenotyping by flow ... maintains the integrity of the white blood ... up to seven days. Patient samples collected ...
Medicine Products: