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GenVec Reports Fourth Quarter And 2012 Year-End Financial Results
Date:3/22/2013

ria Vaccine

  • GenVec signed an agreement worth approximately $3.5 million with the Naval Medical Research Center (NMRC) to support malaria vaccine development.  Under the terms of the agreement, GenVec is responsible for producing clinical supplies of its malaria vaccine, which utilizes its novel, proprietary technology.  The NMRC plans to use this clinical material to assess the safety and efficacy of this next-generation vectored vaccine  using the clinical challenge model developed by the NMRC and the Walter Reed Army Institute of Research (WRAIR) malaria vaccine programs, which now are unified as the U.S. Military Malaria Vaccine Program (USMMVP).  GenVec retains the right to commercialize this novel technology.
     
  • GenVec received a grant of $600,000 over two years from the NIAID to support the Company's malaria vaccine program.  This grant will be used to identify novel antigens for malaria vaccine development.
     
  • Data were presented on GenVec's malaria vaccine program at the American Society of Tropical Medicine and Hygiene (ASTMH) 61st Annual Meeting, which took take place in Atlanta, Georgia on November 11-15, 2012.  Data presented at the conference highlighted GenVec's success in identifying novel antigens for use in its malarial vaccine development program.  Using a proprietary screening technology, GenVec identified new antigens that are as protective as the gold standard, circumsporozoite protein (CSP) in an industry-accepted mouse model of malaria.
    Recent data suggest that new antigens are needed and that CSP, used in vaccines being developed by others, may not be sufficient to generate a protective response in an adequate percentage of people. 
  • Core Technology

  • A research paper on GenVec's new vaccine vectors titled "Modification of Ad5 Hexon Hypervariable Regions Circumvents Pre-Existing Ad5 Neutralizing Antibodies and Induces
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  • SOURCE GenVec, Inc.
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